A5052630982- Toxin Mechanisms and Immunotoxins
- Reproductive tract infections research
- Reproductive System and Pregnancy
- Gene expression and cancer classification
- Bioinformatics and Genomic Networks
- Heat shock proteins research
- Immunotherapy and Immune Responses
- Topic Modeling
- Functional Brain Connectivity Studies
- Gene Regulatory Network Analysis
- Urinary Bladder and Prostate Research
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Virus-based gene therapy research
- Pelvic floor disorders treatments
- Dementia and Cognitive Impairment Research
- Plant Virus Research Studies
- Reproductive Physiology in Livestock
- Peptidase Inhibition and Analysis
- Natural Language Processing Techniques
- Multimodal Machine Learning Applications
- Cardiac Valve Diseases and Treatments
- Anesthesia and Pain Management
- Neuropeptides and Animal Physiology
- Influenza Virus Research Studies
University of Electronic Science and Technology of China
2017-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024-2025
Academy of Medical Sciences
2025
Huazhong University of Science and Technology
2003-2024
Shanghai Center for Brain Science and Brain-Inspired Technology
2024
Tongji Hospital
2024
University of North Carolina at Chapel Hill
2018-2023
Nanjing Medical University
2013-2023
Changzhou No.2 People's Hospital
2023
Microsoft Research Asia (China)
2020-2023
In this work we focus on transferring supervision signals of natural language generation (NLG) tasks between multiple languages. We propose to pretrain the encoder and decoder a sequence-to-sequence model under both monolingual cross-lingual settings. The pre-training objective encourages represent different languages in shared space, so that can conduct zero-shot transfer. After procedure, use data fine-tune pre-trained downstream NLG tasks. Then trained single be directly evaluated beyond...
A novel avian influenza A(H7N9) virus causing human infection emerged in February 2013 China. To elucidate the mechanism of interspecies transmission, we compared signature amino acids viruses from and non-human hosts analysed reassortants 146 with full genome sequences. We propose a genetic tuning procedure continuous acid substitutions reassorting that mediates host adaptation transmission. When early virus, containing ancestor haemagglutinin (HA) neuraminidase (NA) genes similar to...
Osteoarthritis (OA) is a common degenerative joint disease, which characterized by wear of articular cartilage and narrow space, resulting in movement disorder. At present, accurate molecular mechanisms effective interventions are still being explored. Here, we propose that angelica sinensis polysaccharide (ASP) alleviates OA progression activating peroxisome proliferator-activated receptor gamma (PPARγ). Therapeutic effect ASP improving mitochondrial metabolism chondrocytes was evaluated...
The purpose of this study was to investigate the functional connectivity (FC) thalamic subdivisions in patients with juvenile myoclonic epilepsy (JME). Resting state magnetic resonance imaging (fMRI) and diffusion tensor (DTI) data were acquired from 22 JME 25 healthy controls. We first divided thalamus into eight by performing independent component analysis on tracking fibers clustering thalamus-related FC maps. then analyzed abnormal each subdivision compared controls, we investigated...
Chlamydia trachomatis can cause reproductive morbidities after ascending to the upper genital tract of women, and repeated infection lead worse disease. Data related protective immune responses at cervical mucosa that could limit chlamydial cervix and/or prevent reinfection inform vaccine approaches biomarkers risk.We measured 48 cytokines in secretions from women having alone (n = 92) or both endometrial 68). Univariable regression identified associated with differential odds risk,...
Hidradenitis suppurativa (HS) is a chronic, inflammatory condition characterized by recurrent nodules, sinus tracts, comedones, and scarring. often associated with pain decreased quality of life. Limited clinical trial data exist regarding the management acute HS lesions, but experience prospective case series suggest that intralesional triamcinolone may be useful.To compare efficacy to placebo for treatment lesions.This double-blind, randomized, placebo-controlled comparing 10 mg/mL, 40...
LLMs have transformed NLP and shown promise in various fields, yet their potential finance is underexplored due to a lack of thorough evaluations the complexity financial tasks. This along with rapid development LLMs, highlights urgent need for systematic evaluation benchmark LLMs. In this paper, we introduce FinBen, first comprehensive open-sourced benchmark, specifically designed thoroughly assess capabilities domain. FinBen encompasses 35 datasets across 23 tasks, organized into three...
Much attention has been payed to tree shrews for their close phylogenetic relationship with primates, small size, and short reproductive cycle. Especially, they are considered as excellent experiential animals medicine or/and disease research. A nucleotide sequence encoding neuropeptide Y(NPY) precursor cloned from the cDNA library of Tupaia belangeri chinensis. Sequence alignment revealed that homology primate NPY was up 96.9%. The analysis based on shrew a primates.
Problem Chlamydia infections in women can ascend to the upper genital tract, and repeated are common, placing at risk for sequelae. The protective role of anti‐chlamydia antibodies surface exposed antigens ascending incident infection is unclear. Method study A whole‐bacterial ELISA was used quantify chlamydia‐specific IgG IgA serum cervical secretions 151 high‐risk followed longitudinally. Correlations were determined between antibody burden, causal mediation analysis investigated effect on...
Stock movement prediction, a fundamental task in financial time-series forecasting, requires identifying and retrieving critical influencing factors from vast amounts of data. However, existing text-trained or numeric similarity-based retrieval methods fall short handling complex analysis. To address this, we propose the first retrieval-augmented generation (RAG) framework for featuring three key innovations: fine-tuned 1B parameter large language model (StockLLM) as backbone, novel...
Abstract Cognitive functions rely on specific brain circuits involving cortical and subcortical regions. However, how age-related changes in effective connectivity within the prefrontoparietal-thalamo-hippocampal circuit affect cognition remains unclear. This study included 143 healthy older adults (60 to 88 yrs) 124 young (18 44 yrs), using regression dynamic causal modeling analyze resting-state functional magnetic resonance imaging data. Compared adults, showed increased reciprocal...
Air pollution is harmful to human health and restricts economic development, so predicting when where air will occur a challenging important issue, especially in fields of urban planning, factory production activities. In this paper, we propose deep Spatio-Temporal Orthogonal Regularization Residual CNN (ST-OR-ResNet) for prediction. Deep Convolutional Neural Network (CNN) presented capture the complex spatio-temporal relation dynamic biased meteorological data. learning designed avoid...
Combinatorial testing (CT) is a black-box-based technique to generate small number of test cases with focus on covering various interactions among input parameters software system. How effective CT in practice? What are the challenges and issues presented by process applying CT? can these be overcome improve application Although has attracted attention from both academia industry, questions have not been addressed or researched depth based an empirical study industrial settings. From January...
Practical recommender systems experience a cold-start problem when observed user-item interactions in the history are insufficient. Meta learning, especially gradient based one, can be adopted to tackle this by learning initial parameters of model and thus allowing fast adaptation specific task from limited data examples. Though with significant performance improvement, it commonly suffers two critical issues: non-compatibility mainstream industrial deployment heavy computational burdens,...
Linguistic steganography is a technique for hiding information into text carriers. Most of the previous work on linguistic was focused and there were few researches steganalysis. Research attacking methods against plays an important role in security (IS) area. In this paper, detection algorithm based perplexity presented. An experiment to detect segments generated by system NICETEXT carried out. The result our pretty promising. experimental accuracy method classification normal exceeds 99%...
As a paramyxovirus, Newcastle disease virus (NDV) has the ability to edit its P (phosphoprotein) gene synthesize three kinds of viral protein (P, V and W).It is technically very diffi cult diff erentiate P, W mRNAs, little was known about NDV regulation RNA-editing frequency.To investigate rules RNA editing, ratio gene-derived transcripts W) determined by sequencing at erent time points post-infection.Th e results showed unstable mRNA points, frequency editing signifi cantly increased early...
Abstract Background and Aim : It has been suggested that Chlamydia is an organism may have the potential to cause inflammatory bowel disease (IBD) in susceptible individuals. pneumoniae emerged as important human pathogen last decade. The objective of present study was investigate frequency presence C. DNA intestinal biopsies from patients with IBD non‐IBD controls. Methods extracted 222 colonoscopic biopsies, which were obtained 11 Crohn's (CD), 18 ulcerative colitis (UC) 37 control...
Complex graphics of nonlinear dynamical systems perform vital role in many fields, e.g., image compression or encryption, art, science, and so on. Antifractals are generated by applying a map recursively to an initial point complex plane that have become significant area research these days. The purpose this paper is investigate the dynamics antifractals like anti-Julia sets, tricornsand multicorns antiholomorphic polynomials via CR iteration scheme with s-convexity. Many beautiful aesthetic...
We cloned the Rhodococcus opacus (strain DSM 44193) tipA gene, which encodes two translation products, TipAL and TipAS. The gene products are homologous to Streptomyces spp. TipAS proteins, respectively. promoter is highly active protein predominantly accumulated in R. cells when inducer of transcription, thiostrepton, was presented culture medium. found that thiostrepton also induced expression an endogenous TipA-family erythropolis JCM3201). minimal region defined (57 bp) conserved...
1 Summary Gene co-expression network differential analysis is designed to help biologists understand gene expression patterns under different conditions. We have implemented an R package called MODA (Module Differential Analysis) for analysis. Based on transcriptomic data, can be used estimate and construct condition-specific networks, identify differentially expressed subnetworks as conserved or condition specific modules which are potentially associated with relevant biological processes....