- Phytoestrogen effects and research
- Sepsis Diagnosis and Treatment
- Phytochemicals and Antioxidant Activities
- Effects and risks of endocrine disrupting chemicals
- Birth, Development, and Health
- Gut microbiota and health
- Tea Polyphenols and Effects
- Recycling and Waste Management Techniques
- Liver Disease Diagnosis and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Elbow and Forearm Trauma Treatment
- Optical Coatings and Gratings
- Ultrasound and Hyperthermia Applications
- Toxic Organic Pollutants Impact
- Orthopedic Surgery and Rehabilitation
- Additive Manufacturing Materials and Processes
- Per- and polyfluoroalkyl substances research
- Diet and metabolism studies
- Hormonal and reproductive studies
- Surface Roughness and Optical Measurements
- Musculoskeletal Disorders and Rehabilitation
- Extraction and Separation Processes
- Additive Manufacturing and 3D Printing Technologies
- Safe Handling of Antineoplastic Drugs
- Natural product bioactivities and synthesis
Nanjing University of Chinese Medicine
2020-2024
Fudan University
2013-2023
Zhongshan Hospital
2019-2023
Shanghai Normal University
2023
Sun Yat-sen University
2021-2023
Chongqing Medical University
2023
The First Affiliated Hospital, Sun Yat-sen University
2021-2023
Shanghai Institute of Pharmaceutical Industry
2023
Central South University
2009-2022
University of Hong Kong
2022
Abstract Additive manufacturing (AM) technology is considered one of the most promising technologies in aerospace and defense industries. However, AM components are known to have various internal defects, such as powder agglomeration, balling, porosity, cracks thermal/internal stress, which can significantly affect quality, mechanical properties safety final parts. Therefore, defect inspection methods important for reducing manufactured defects improving surface quality components. This...
Designing adsorption materials with high capacities and selectivities is highly desirable for precious metal recovery. Desorption performance also particularly crucial subsequent recovery adsorbent regeneration. Herein, a metal-organic framework (MOF) material (NH2 -UiO-66) an asymmetric electronic structure of the central zirconium oxygen cluster has exceptional gold extraction capacity 2.04 g g-1 under light irradiation. The selectivity NH2 -UiO-66 ions up to 98.8 % in presence interfering...
Gut dysbiosis has been reported in chronic hepatitis B (CHB) infection, however its role CHB progression and antiviral treatment remains to be clarified. Herein, the present study aimed characterize gut microbiota (GM) patients with virus infection-associated liver diseases (HBV-CLD) by combining microbiome metabolome analyses evaluate their effects on peripheral immunity. Fecal samples from HBV-CLD (n = 64) healthy controls 17) were collected for 16s rRNA sequencing. metabolomics was...
Background Dysfunction of the immune system would disturb intestinal homeostasis and lead to inflammatory bowel disease (IBD). Dendritic cells (DCs) help maintain immediately respond pathogens or injuries once mucosa barriers are destroyed during IBD. G protein-coupled receptors(GPR)174 is an essential regulator immunity that widely expressed in most cells, including DCs. However, role GPR174 regulating function DC colitis has not been investigated. Methods Dextran sodium sulfate (DSS) was...
Abstract Background Evidence of associations between prenatal exposure to perfluoroalkyl substances (PFASs) and fetal thyroid hormones (THs) is controversial, few studies have estimated the associations, while addressing high correlations among multiple PFASs. We aimed examine PFAS hormone concentrations in cord blood. Methods A total 300 mother-infant pairs from Shanghai-Minhang Birth Cohort Study were included. measured eight PFASs maternal plasma samples collected at 12–16 gestational...
Abstract Designing adsorption materials with high capacities and selectivities is highly desirable for precious metal recovery. Desorption performance also particularly crucial subsequent recovery adsorbent regeneration. Herein, a metal–organic framework (MOF) material (NH 2 ‐UiO‐66) an asymmetric electronic structure of the central zirconium oxygen cluster has exceptional gold extraction capacity 2.04 g −1 under light irradiation. The selectivity NH ‐UiO‐66 ions up to 98.8 % in presence...
Background: The gut plays an important role in the development of sepsis and acts as one possible drivers multiple-organ dysfunction syndrome. This study aimed to explore dynamic alterations microbiota its metabolites septic patients at different stages intensive care unit (ICU) admission. Methods: In this prospective observational study, a total 109 fecal samples from 23 patients, 16 nonseptic ICU 10 healthy controls were analyzed. 16S rRNA gene sequencing ultra-performance liquid...
The microbiota profile of children changes with age. To investigate the differences in gut 1- and 4-year-old children, we collected fecal samples sequenced V3-V4 hypervariable region 16S rRNA gene via high-throughput DNA sequencing. From phylum to species level, underwent significant abundance phyla Proteobacteria Actinobacteria declined age, whereas Firmicutes Bacteroidetes increased age dominated 4-year-olds. intestinal environment at four is closer maturity. Hence, Bifidobacterium...
Abstract Animal studies demonstrated that paternal alcohol exposure before conception increases the risk of adverse neurodevelopment in offspring, but limited evidence is known humans. Based on Shanghai-Minhang Birth Cohort Study, we aimed to examine associations between preconceptional consumption and child behavioral problems. Paternal during last 3 months was obtained by maternal report. Children born fathers who drank at least once a week were classified as exposed. Child problems...
Alterations in bile acid (BA) profiles are closely associated with adverse outcomes pregnant women and their offspring may be one potential pathway underlying the related metabolic effects of per- poly-fluoroalkyl substances (PFAS) exposure. However, evidence associations between PFAS exposure BA is scarce. This study examined individual mixture women. We obtained quantitative data on plasma concentrations 13 15 BAs 645 from Jiashan birth cohort. In Bayesian kernel machine regression models,...
Endothelium injury and coagulation dysfunction play an important role in the pathogenesis of sepsis. Soluble thrombomodulin (sTM), tissue plasminogen activator-inhibitor complex (t-PAIC), thrombin-antithrombin (TAT) α2-plasmin inhibitor-plasmin (PIC) are biomarkers endothelium dysfunction. This study aimed to explore prognostic values diagnostic performance for septic shock sepsis-induced disseminated intravascular (DIC) endothelial biomarkers.We conducted observational on patients with...
Subcritical water extraction (SWE) of bioactive extracts from Radix Puerariae (RP) was firstly optimized by response surface methodology (RSM) and its efficiency compared with two traditional volatile isolation methods including hot (HWE) ethanol reflux (ERE). The optimal SWE parameters were as follows: temperature 141 °C, time 58 min, liquid-solid ratio l 23:1 mL/g. Under these conditions, yield 28.9 ± 0.2%, which slightly higher than that obtained ERE, more two-fold the value HWE...