- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Medical Research and Treatments
- Hematological disorders and diagnostics
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Youth Substance Use and School Attendance
- Endometrial and Cervical Cancer Treatments
- Bacterial Identification and Susceptibility Testing
- Radiomics and Machine Learning in Medical Imaging
- Public Relations and Crisis Communication
- Reproductive tract infections research
- Inflammatory Bowel Disease
- Lipid metabolism and disorders
- Cancer, Lipids, and Metabolism
- Cancer survivorship and care
- Family Support in Illness
- Lymphoma Diagnosis and Treatment
- Eosinophilic Esophagitis
- Cancer Risks and Factors
- Digital Marketing and Social Media
- Cancer-related cognitive impairment studies
First People's Hospital of Chongqing
2025
Chongqing University
2025
Hunan Cancer Hospital
2020-2025
Central South University
2020-2025
Linyi People's Hospital
2023-2024
Weatherford College
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Jinzhou Medical University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2023
Abstract Background Depression and sleep disturbances are associated with increased risks of various diseases mortality, but their impacts on mortality in cancer survivors remain unclear. The objective this study was to characterize the independent joint associations depressive symptoms outcomes survivors. Methods This population-based prospective cohort included aged ≥ 20 years ( n = 2947; weighted population, 21,003,811) from National Health Nutrition Examination Survey (NHANES) 2007–2018...
Background and Objectives Elevated preoperative neutrophil–lymphocyte ratio (NLR) platelet–lymphocyte (PLR) predict survival rates among patients with several types of cancer. The current study sought to clarify whether NLR PLR are clinically useful independent prognostic indicators adenocarcinomas the esophagogastric junction (AEG) undergoing curative resections (i.e., R0 resections). Methods A total 327 who underwent for AEG were enrolled in study. Data concerning demographic parameters,...
Background Plasma D-dimer levels have been shown to be high in advanced tumor stage patients and can used predict clinical outcome cancer patients. As most exhibit asymptomatic metastasis, which contributes early recurrence after surgery, we hypothesized that plasma with potential metastasis. Methods We enrolled 1042 primary gastric three multiple centers Northwest China examined using the latex-enhanced immunoturbidimetric assay (LEIA) method. were compared clinicopathological...
Abstract Background There has been little research on the perioperative D‐dimer levels in oesophageal cancer patients. Plasma can be used to predict outcome Methods A group of 66 patients and a control 12 with benign disease were enrolled this cohort study. The plasma during pre‐operation 3rd 9th day post‐operation periods prospectively examined analysed between two groups. also compared clinicopathological characteristics 3‐year survival Results increased both groups after surgery, but they...
To investigate the role of platelet-to-lymphocyte ratio (PLR) in complete pathological response (pCR) breast cancer (BC) patients after neoadjuvant chemotherapy (NAC), as well to establish and validate a nomogram for predicting pCR.BC diagnosed treated First Affiliated Hospital Xi'an Jiaotong University from January 2019 June 2022 were included. The correlation between pCR clinicopathological characteristics was analyzed by Chi-square test. Logistic regression analysis performed evaluate...
ObjectivesGiven the modest efficacy of docetaxel in advanced non-small cell lung cancer (NSCLC), this study assesses therapeutic potential and safety profile anlotinib combination with compared to monotherapy as a second-line therapy for patients NSCLC.Materials MethodsIn phase II study, NSCLC experiencing failure first-line platinum-based regimens were randomized 1:1 ratio receive either plus or alone. Primary endpoint was progression-free survival (PFS), overall (OS), objective response...
Maintaining effective disease control in patients with inflammatory bowel (IBD) is both a significant goal and challenge. Drawing on the Common-Sense Model of Self-Regulation (CSM) related research, this study investigates how IBD activity status influences through direct indirect pathways. A cross-sectional survey was conducted among 310 who attended tertiary general hospital, leader Alliance Group Chongqing City, between March August 2024. Structural equation modeling (SEM) utilized to...
BACKGROUND Insomnia is a common sleep disorder that negatively impacts quality of life and frequently comorbid with depression anxiety. Chronic insomnia affects approximately 15% the global population, higher prevalence among females elderly. While existing research suggests bidirectional relationship between emotional disorders, specific impact severity on depression, anxiety, remains unclear. This study investigates correlation these factors in psychiatric outpatients, hypothesizing...
2549 Background: The high-dimensional classification information of peripheral blood mononuclear cells can provide abundant efficacy and prognosis-related data. However, in the field immunotherapy for extensive-stage small cell lung cancer (ES-SCLC), biomarkers that predict prognosis need to be explored clarified. Methods: Cytometry by Time-Of-Flight (CyTOF) was applied dynamic monitoring using clinical resources such as from ES-SCLC patients. By labeling following proteins: CD45, CD3, CD4,...
Abstract The aim of this study was to investigate the clinical characteristics Chlamydia psittaci pneumonia and evaluate diagnostic value Metagenomic Next‐Generation Sequencing (mNGS). A total 44 patients diagnosed with using mNGS were retrospectively analysed. demographic features, laboratory data, imaging findings outcomes collected. Results showed that 65.91% had a history exposure poultry or birds. All presented fever. Apart from systemic respiratory symptoms, some also digestive...
The prognostic value of preoperative white blood cell to hemoglobin ratio (WHR) and fibrinogen albumin (FAR) in colorectal cancer (CRC) is unknown. purpose this study was analyze the correlation between WHR FAR prognosis CRC patients. retrospective analyzed medical records 207 patients with who were admitted Linyi People's Hospital June 1, 2017 2021. receiver operator curve used determine cutoff 4.604 for 0.086 FAR, divided into high low groups comparative analysis clinical data. Cox...
The prognostic value of peripheral blood hemoglobin/red cell distribution width ratio (HRR) in colorectal cancer (CRC) is unclear. aim this study was to analyze the correlation between HRR and prognosis CRC. A retrospective analyzed medical records 284 CRC patients who attended Linyi People Hospital June 1, 2017 2021. optimal diagnostic cutoff for hemoglobin (Hb)/erythrocyte determined by ROC curve as 3.098, were divided into high- low-level groups comparative analysis clinical data....
e21703 Background: Anlotinib is an oral VEGFR, FGFR, PDGFR and c-Kit tyrosine kinase inhibitor, which can prolong both PFS OS of refractory advanced NSCLC patients in phase III trial: ALTER0303. The combination docetaxel ramucirumab/nintedanib had been demonstrated activity the second line therapy setting for NSCLC. We performed ALTER-L018 to assessed safety efficacy anlotinib with EGFR-wild type (NCT03624309). Methods: Patients (pts) NSCLC, who failed first-line platinum-based chemotherapy,...
Objective To provide support for clinical treatment and effective prevention of ulcer hemorrhage in upper digestive tract by exploring the current status this condition elderly people possible influencing factors.Methods The data on 331 patients who had been diagnosed our hospital during period January 2008 to December 2012 were retrospectively analyzed.The divided into group (≥60 years,114 patients) non-elderly (< 60 years,217 according their ages.The etiologies coexisting diseases analyzed...
Objective: To explore the risk factors in HBV-associated hepatocellular carcinoma (HCC) patients with early recurrence after ablation and to establish predictive model. Methods: A total of 81 HBV-related HCC who underwent from January 2016 December were included Beijing Youan Hospital, including 66 males 15 females. Standard medical records collected, which summarized as follows: demographic data, liver function, number size tumors modality ablation. Univariate multivariate analysis...
Objective To investigate the relationship between perineural invasion (PNI) and clinicopathological features as well prognosis of cervical squamous carcinoma. Methods The clinico-pathological data 256 patients with carcinoma (ⅠB1-ⅡA2) treated extensive resection pelvic lymphadenectomy in Shanxi Provincial Cancer Hospital from January 2010 to December 2013 were retrospectively analyzed. PNI tumor area pathological sections was observed by using microscope. The effect on postoperative...
Background Mental health is a public problem of great concern. Previous studies show that textual features and individual psychological characteristics can influence the effect receiving information. Purpose This study explores whether persuasiveness teenager students’ mental education while considering risk preference. Methods From November to December 2021, cross-sectional was conducted among 1,869 students in grade 7–12 Chongqing, China. Wilcoxon signed-rank test, multiple logistic...
e21186 Background: Docetaxel is one of the standard second-line treatments for advanced non-small cell lung cancer (NSCLC), but effect limited. The combination docetaxel and antiangiogenic drug (ramucirumab/nintedanib) has demonstrated antitumor activity as therapy in NSCLC. Anlotinib, an oral multi-target angiogenesis TKI targeting VEGFR, FGFR, PDGFR c-Kit, can prolong both PFS OS refractory NSCLC patients phase III trial (ALTER0303). We conducted ALTER-L018 to evaluate improvement efficacy...