A5102919345- Hip and Femur Fractures
- Tendon Structure and Treatment
- Plant biochemistry and biosynthesis
- Invertebrate Immune Response Mechanisms
- Bone fractures and treatments
- Diabetic Foot Ulcer Assessment and Management
- Orthopedic Infections and Treatments
- Wound Healing and Treatments
- COVID-19 and healthcare impacts
- Shoulder Injury and Treatment
- DNA Repair Mechanisms
- COVID-19 Clinical Research Studies
- Sports injuries and prevention
- Insect Resistance and Genetics
- Knee injuries and reconstruction techniques
- Pelvic and Acetabular Injuries
- Hydrogels: synthesis, properties, applications
- Elbow and Forearm Trauma Treatment
- Osteomyelitis and Bone Disorders Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Salivary Gland Disorders and Functions
- Bacterial biofilms and quorum sensing
- Bone Metabolism and Diseases
- Lipid Membrane Structure and Behavior
- Genetic and Kidney Cyst Diseases
Huazhong University of Science and Technology
2017-2025
Union Hospital
2019-2025
Hebei University
2019-2024
Henan University of Science and Technology
2024
Shandong Normal University
2022-2023
Sixth Affiliated Hospital of Xinjiang Medical University
2023
Xinjiang Medical University
2023
Union Hospital
2017-2022
Wuhan University
2021
Wuhan Union Hospital
2021
Thetreatment of infected wounds is currently a major challenge in clinical medicine, and enhancing antimicrobial angiogenic capacity one the most common strategies. However, current treatment makes it difficult to balance effect early stage later stages wound healing, leading an increased rate poor prognosis. Here, we present nanoconductive hydrogel EF@S-HGM, consisting HGM with ECGS, FMLP, SWCNT. The host-guest supramolecular macromolecule (HGM) biocompatible can be injected situ wound....
Evidence is required to evaluate the effectiveness of population-level endoscopic screening for esophageal cancer (EC). In this study, 5,632 permanent residents aged 25-65 years from 6 villages in Hua County, Henan Province, China, were defined as cohort and offered intensive screening. Residents all 914 remaining County included control cohort, age-sex standardization was used calculate expected numbers EC upper gastrointestinal (GI) tract cases deaths cohort. The assessed by comparing...
Hip fractures in the elderly account for more than half of osteoporotic and represent a substantial economic social burden. Novel coronavirus pneumonia (COVID-19), which began to spread December 2019, has created challenges management hip fracture patients, not only by influencing choice operation postoperative rehabilitation methods, but also generating new risks medical staff. During this period, our infection orthopedic treatment unit center epidemic area effectively treated 82 patients...
Although the immune system is well recognized as a key player in fracture repair, exact mechanisms, particularly role of regulatory T-cells (Tregs), have not yet been established. Our increased understanding Tregs and exosomes involved organ repair creates opportunity application derived Exosomes (TregD-Exos) modulation repair. In present study, we report that TregD-Exos containing miR-142-3p can be shuttled into bone mesenchymal stem cells (BMSCs) Human umbilical vein endothelial (HUVECs)...
To compare the clinical effect of 3D-printed template technology with X-ray fluoroscopy in assisting surgery for sacroiliac screws placement. Institutional review board-approved retrospective analysis. The data 31 cases complex injury between January 2015 and December 2016 were analyzed. There 16 patients, males 11 females 5, who underwent assisted by group, that contemporaneous 15 4, traditional gathered as group. All those patients followed up more than 6 months. operation time times each...
During meiosis, cohesin and meiosis-specific proteins organize chromatin into an axis-loop architecture, coordinating homologous synapsis, recombination, ordered chromosome segregation. However, how the meiotic axis is assembled differentiated with progression remains elusive. Here, we explore dynamic recruitment of two long arms bivalent proteins, LAB-1 LAB-2, in Caenorhabditis elegans. LAB directly interact core HORMA complexes weak interactions contribute to their recruitment. phase...
Recent studies showed that kidney-specific inactivation of Kif3a produces kidney cysts and renal failure, suggesting kinesin-mediated intracellular transportation is important for the establishement maintenance epithelial cell polarity normal nephron functions. Kif5b, one most conserved kinesin heavy chain, mouse homologue human ubiquitous Kinesin Heavy Chain (uKHC). In order to elucidate role Kif5b in development function, it essential establish its expression profile within organ....
Background This study aims to investigate the impact of varying coronal alignments femoral prostheses on stress and strain distributions within lateral compartment following unicompartmental knee arthroplasty (UKA) in patients with normal bone density osteoporosis using finite element analysis. Additionally, it examines relationship between progression osteoarthritis postoperatively. Methods UKA models were developed for both osteoporotic conditions a validated model knee. Seven alignment...
Multiple rib fractures caused by trauma are common injuries and the internal fixation methods of these have been paid more attention surgeons. Absorbable plates screws effective way to treat fractures, but there no reports on which type screw method is most effective. In this study, finite element analysis was used study effects five different types anterior rib, lateral posterior rib. The model ribs reconstructed from CT images, pressure (40 kPa) intercostal force (30 N) surfaces were...
Neocaridina denticulata sinensis can serve as a good model organism for decapods basic studies. In crustaceans, molting is an indispensable process and requires precise coordination. However, the relationship between neuroendocrine remains elusive. Farnesyl pyrophosphate synthase (FPPS) participates in production of methyl farnesoate (MF). this study, molecular changes N. eyestalk after silencing NdFPPS were analyzed. A total 3320 differential expressed genes identified. 2002 DEGs...
Farnesyl pyrophosphate synthase (FPPS) is a key enzyme in the terpenoid biosynthesis pathway, responsible for converting isopentenyl (IPP) and dimethylallyl (DMAPP) into farnesyl (FPP). In crustaceans, FPPS plays an important role various physiological processes, particularly synthesizing crustacean-specific hormone methyl farnesoate (MF). This study analyzed evolutionary differences physicochemical properties, subcellular localization, gene structure, motif composition of Neocaridina...
Methyl farnesoate (MF) is considered the equivalent of JH in crustaceans and plays an essential role many crucial physiological processes. It believed that farnesyl pyrophosphate synthase (FPPS) biosynthesis mevalonate, which a branch JH/MF pathway. The full-length cDNA FPPS (NdFPPS) from Neocaridina denticulata sinensis was isolated characterized, deduced amino acid NdFPPS contained polyprenyl_synt domain. In addition to its ubiquitous tissue expression, significantly expressed ovary. vivo...
Objective To investigate the causes and treatment strategy for postoperative complications following trans-articular external fixation in elder patients with distal radius fracture of type C3. Methods The clinical data were retrospectively studied 226 C3 who had been treated by from January 2011 to December 2016 at Department Orthopaedics, Union Hospital. Of them, 42 (18.6%) suffered complications. They 12 men 30 women, aged 65 83 years (average, 68.4 years). Results Of...
Methyl farnesoate is considered the equivalent of JH in crustaceans and plays an essential role many crucial physiological processes. FPPS a key enzyme mevalonate pathway, JH/MF biosynthesis pathway branch. The full-length cDNA (NdFPPS) from Neocaridina denticulata sinensis was isolated characterized，and deduced amino acid contained polyprenyl_synt domain. To further investigate function NdFPPS, dsRNA interference-mediated gene silencing carried out vivo. Comparison, annotation...
Currently, we found that double reverse traction repositor (DRTR) is a treatment with operation convenience and fast in our clinical work. However, the efficacy safety of DRTR reduction unstable intertrochanteric fractures elderly patients remain unknown. Therefore, study aimed to compare table (TT) patients.From October 2018 December 2020, were reviewed. 22 treated TT 20 met inclusion criteria this study, baseline characteristics recorded. The time, incision length intraoperative blood loss...
With the outbreak of novel coronavirus pneumonia (NCP) induced by 2019 (2019-nCoV) in Wuhan, Hubei Province December 2019, more and suspected or confirmed cases have been found various regions China. Although China has adopted unprecedented strict quarantine closed management measures to prevent spreading disease, Department Traumatic Orthopedics may still manage NCP patients with open fractures severe trauma that require emergency surgery. Therefore, identification 2019-nCoV infection as...