- Weed Control and Herbicide Applications
- Antenna Design and Analysis
- Nanoparticle-Based Drug Delivery
- Pesticide and Herbicide Environmental Studies
- Anesthesia and Sedative Agents
- Plant-based Medicinal Research
- Thyroid Cancer Diagnosis and Treatment
- Advanced Antenna and Metasurface Technologies
- Fungal Plant Pathogen Control
- Boron Compounds in Chemistry
- melanin and skin pigmentation
- Advanced MIMO Systems Optimization
- Energy Harvesting in Wireless Networks
- Cardiomyopathy and Myosin Studies
- Microwave Engineering and Waveguides
- Biochemical and Structural Characterization
- Language Development and Disorders
- Thyroid and Parathyroid Surgery
- Cell Adhesion Molecules Research
- Full-Duplex Wireless Communications
- Opinion Dynamics and Social Influence
- Click Chemistry and Applications
- Glioma Diagnosis and Treatment
- Radiation Detection and Scintillator Technologies
- Epigenetics and DNA Methylation
The University of Queensland
2007-2024
Soochow University
2023
First Affiliated Hospital of Soochow University
2023
Shanxi Medical University
2021-2023
First Hospital of Shanxi Medical University
2021-2023
GTx (United States)
2022
Institute of Electronics
2021
Stanford University
2019-2020
Huawei Technologies (China)
2015
Jiangxi Normal University
2015
Advances in precision molecular imaging promise to transform our ability detect, diagnose and treat disease. Here, we describe the engineering validation of a new cystine knot peptide (knottin) that selectively recognizes human integrin αvβ6 with single-digit nanomolar affinity. We solve its 3D structure by NMR x-ray crystallography validate leads 3 different radiolabels pre-clinical models cancer. evaluate lead tracer's safety, biodistribution pharmacokinetics healthy volunteers, show...
Abstract Acetohydroxyacid synthase (AHAS) is the target for more than 50 commercial herbicides; first applied to crops in 1980s. Since then, 197 site-of-action resistance isolates have been identified weeds, with mutations at P197 and W574 most prevalent. Consequently, AHAS risk of not being a useful crop protection. To develop new herbicides, functional understanding explain effect these on activity required. Here, we show that can two effects (i) reduce binding affinity herbicides (ii)...
Amidosulfuron (AS) is from the commercial sulfonylurea herbicide family. It highly effective against dicot broad-leaf weeds. This targets acetohydroxyacid synthase (AHAS), first enzyme in branched chain amino acid biosynthesis pathway. Here, we have determined crystal structure of AS complex with wildtype Arabidopsis thaliana AHAS (AtAHAS) and resistance mutant, S653T. In both structures, cofactor, ThDP, modified to a peracetate adduct, consistent time-dependent accumulative inhibition....
Abstract Background : Electropalatographic investigations have revealed that a proportion of children with articulation/phonological disorders exhibit undifferentiated lingual gestures, whereby the whole tongue contacts palate simultaneously during consonant production. These gestures been interpreted to reflect ‘motor constraint’, tip and body incapable operating independently. Aims The present study aimed provide further insight into speech motor control abilities by using electromagnetic...
Triasulfuron is a commercial herbicide of the sulfonylurea family. This compound targets acetohydroxyacid synthase (AHAS, E.C. 2.2.1.6), first enzyme in branched chain amino acid biosynthesis pathway. Here, we have determined crystal structures
The 4th generation (4G) LTE (Long Term Evolution) mainly focuses on spectrum assets lower frequency bands. next cellular communication would aim to develop utilization higher bands fully utilize the all between 300MHz 100GHz, with primary below 6GHz and complimentary above 6GHz. Time Division Duplex (TDD) is promising for 3GHz due no requirement paired band, channel reciprocity Multiple-Input-Multiple- Output (MIMO) cost-effectiveness. TDD will play an important role in communication. In...
Objective The aim of this study was to evaluate the effect vitamin E and supragingival scaling with C on salivary glands patients differentiated thyroid carcinoma after 131 I treatment. Methods A total 89 prospective were enrolled randomly divided into following groups: group ( n = 30, A), B) 29, C). Using functional indices (e.g. maximum uptake fraction, index, excretion secretion time rate), changes in gland functions before a month treatment assessed by dynamic imaging gland. Results We...
Thyroid nodule (TN) is one or more abnormal lump structures in the thyroid gland parenchyma caused by genetic, environmental, and other factors. It most common disease clinics. Microwave ablation (MWA) can significantly reduce volume effectively symptoms nodules. However, patient's negative emotions during perioperative period may affect postoperative recovery. This study explored risk factors of patients its impact on patient prognosis. data provides a basis for clinical psychological...
Toothache, a common disorder afflicting most people, shows distinct features at different clinical stages. This study aimed to depict metabolic changes in brain and investigate the potential mechanism involved aberrant affective behaviors during natural process of toothache.We investigated spatiotemporal patterns function course toothache rat model dental pulp injury (DPI) by using positron emission tomography (PET).Glucose metabolism peaked on 3rd day gradually decreased several regions...
Learning is a kind of important human behavior to acquire knowledge.This paper discussed temporal characteristics network course learning on dynamics.Firstly, the students data for 8-weeks are collected from online platform.Then, work used Maximum Likelihood Estimation(MLE) method estimating power exponent interval time distribution, and introduced Kolmogorov-Smirnov(KS) test power-law hypothesis .The empirical research results show that: both in group individual level, obey...
Four different arrangements of polarization diversity microstrip patch antennas that are suitable for mobile terminal applications have been investigated. Both experimental and calculated results given, showing the coupling correlative coefficient signals depend on relative directions, distance between two /spl epsiv//sub r/ substrate used antennas. For sake coupling, space limitations, back-to-back integration configuration is relatively better to put into a (e.g., laptops wireless network...
MIMO (multiple-input multiple-output) systems have been widely used in the new generation mobile communications because of their large capability, high speed and low code errors. Transmitting receiving antenna are very important parts whole systems. And designs will directly affect system's performance. In this paper, a type printed-dipole antennas is introduced. The theoretical practical testing show that can make full use space frequency resources it fit for spatial diversity
In this paper, a broadband differentially fed circularly polarized (CP) patch antenna is designed. Combined with the field distribution of antenna, double-layer differential microstrip feeding structure proposed to form circular polarization. The CP works around 28.0 GHz, −10 dB impedance bandwidth and 3-dB 13.2% 7.0%, respectively. Within achieved bandwidth, radiation pattern has excellent conformality symmetry. height only <tex xmlns:mml="http://www.w3.org/1998/Math/MathML"...
The prognosis of patients with dilated cardiomyopathy (DCM) is poor and new indicators are urgently needed to predict lethal cardiac events. This study aimed investigate the value summed motion score (SMS) in predicting death DCM using gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI).Eighty-one who underwent 99mTc-MIBI SPECT MPI were retrospectively enrolled divided into survivor groups. functional parameters left ventricle including SMS measured...
Acetohydroxyacid synthase (AHAS), also known as acetolactate synthase, is the target of more than 50 commercial herbicides.[1] To date, seven structures sulfonylurea (SU) class herbicides have been solved in complex with a plant AHAS (i.e.Arabidopsis thaliana (AtAHAS)), while only one structure triazolopyrimidine (TP) has solved.[2,3] Here, we determined imazosulfuron (3.0 Å resolution) (Figure1.A) and flumetsulam (2.75 (Figure 1. B) AtAHAS.Imazosulfuron broad-spectrum herbicide used to...
Abstract Purpose Toothache, a common disorder afflicting most people, shows distinct features at different clinical stages. This study aimed to depict metabolic changes in brain and investigate the potential mechanism involved aberrant affective behaviors during natural process of toothache. Methods We investigated spatiotemporal patterns function course toothache rat model dental pulp injury (DPI) by using positron emission tomography (PET). Results Glucose metabolism peaked on 3 rd day...