- Muscle activation and electromyography studies
- Neurological disorders and treatments
- Cardiac Arrest and Resuscitation
- Spinal Cord Injury Research
- Cerebral Palsy and Movement Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Mesenchymal stem cell research
- Shoulder Injury and Treatment
- Esophageal and GI Pathology
- Vitamin D Research Studies
- Cancer Cells and Metastasis
- HIV Research and Treatment
- Plant-based Medicinal Research
- Motor Control and Adaptation
- Genetic Neurodegenerative Diseases
- Trauma and Emergency Care Studies
- Tryptophan and brain disorders
- Gout, Hyperuricemia, Uric Acid
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neuroendocrine Tumor Research Advances
- Stroke Rehabilitation and Recovery
- Circadian rhythm and melatonin
- Sleep and Wakefulness Research
- HIV-related health complications and treatments
Second Affiliated Hospital of Zhejiang University
2021-2025
Zhejiang University
2014-2024
First Affiliated Hospital Zhejiang University
2017-2024
Women and Children’s Health Research Institute
2018
University of Alberta
2018
Jilin Normal University
2015
Harbin Medical University
2015
Uppsala University
2015
Georgetown University
2015
First Affiliated Hospital of Harbin Medical University
2015
The aim of this study is to assess the impacts urban green space on depressive symptoms among Chinese residents aged 45 and older. In total, 7397 respondents were included in study. Each respondent participated China Health Retirement Longitudinal Study Wave 3 (2015). Environmental-level variables retrieved from National Bureau Statistics database. Both unadjusted adjusted methods used multilevel regression analysis. Almost one-third sample population suffered (31.20%). logistic model showed...
Arm movements modulate leg activity and improve gait efficiency; however, current rehabilitation interventions focus on improving walking through gait-specific training do not actively involve the arms. The goal of this project was to assess effect a strategy involving simultaneous arm cycling after incomplete spinal cord injury (iSCI). We investigated 1) non-gait-specific 2) active involvement during changes in over ground capacity. Participants with iSCI were assigned arm-leg (A&L) or...
Basal forebrain cholinergic neurons are proposed as a major neuromodulatory system in inflammatory modulation. However, the function of basal sepsis is unknown, and neural pathways underlying anti-inflammation remain unexplored.Animal research.University research laboratory.Male wild-type C57BL/6 mice ChAT-ChR2-EYFP (ChAT) transgenic mice.The neuronal activity was manipulated optogenetically. Cecal ligation puncture produced to induce sepsis. Left cervical vagotomy 6-hydroxydopamine...
The globus pallidus (GP) is emerging as a critical locus of basal ganglia control motor activity, but the exact role GABAergic GP neurons remain to be defined. By targeted expression channelrhodopsin 2 (ChR2) in using VGAT-ChR2-EYFP transgenic mice, we showed that optogenetic stimulation right produced hyperkinesia. Optogenetic increased c-Fos-positive cells GP, M1 cortex and caudate-putamen (CPu), decreased entopeduncular nucleus (EPN), compared contralateral hemisphere. In agreement with...
Impaired ankle dorsal and plantar flexor function is a frequent sequela of stroke. A better assessment muscle activation would be highly significant for stroke rehabilitation. The challenge in implementing current electromyography (EMG)-based assessments due to problems with the variability individuality EMG profiles during walking. We have been studying new technique using synergy method quantify characteristics that underlie address this issue.We processed surface signals from muscles gait...
Chronic heart failure (CHF) increases sympathoexcitation through angiotensin II (ANG II) receptors (AT1R) in the paraventricular nucleus (PVN). Recent publications indicate both γ-aminobutyric acid B-type receptor 1 (GABBR1) and microRNA-7b (miR-7b) are expressed PVN. We hypothesized that ANG regulates homeobox D10 (HoxD10), which miR-7b other tissues.Ligation of left anterior descendent coronary artery rats caused CHF sympathoexcitation. PVN expression AT1R, HoxD10, was increased, whereas...
To the Editor: Early bystander cardiopulmonary resuscitation (CPR) is crucial for survival and long-term quality of life patients with out-of-hospital cardiac arrest.[1] Training schoolchildren how to perform CPR highly recommended by many countries health organizations, including World Health Organization.[2,3] Schoolteachers previous training are suggested as instructors teach schoolchildren.[4,5] The knowledge teachers very important their willingness teaching.[6,7] A 6-year longitudinal...
Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder in which the adrenal cortex fails to respond appropriately stimulation by adrenocorticotropic hormone (ACTH) produce cortisol. The disease characterized laboratory testing and markedly elevated ACTH levels. FGD may present infancy or early childhood with symptoms related low cortisol high ACTH, such as hyperpigmentation, severe hypoglycemia, failure thrive recurrent infections. Mutations MC2R accessory protein...
Abstract Background Outcomes derived from longitudinal self-reported health-related quality of life measures can be confounded by response shift. This study was aimed to detect shift among patients with hypertension attending a community-based disease management program. Methods 240 consecutive consulting or follow-up diagnosed were recruited. The Short Form 36-item Health Survey self-administered at 12 community health service stations baseline and four weeks after the 4-step structural...
Abstract Background The involvement of quality life as the UNAIDS fourth 90 target to monitor global HIV response highlighted development patient-reported outcome (PRO) measures help address holistic needs people living with HIV/AIDS (PLWHA) beyond viral suppression. This study developed and tested preliminary measurement properties a new (PROHIV-OLD) measure designed specifically capture influences on patients aged 50 older in China. Methods Ninety-three were interviewed solicit items two...
We aimed to describe anesthesiologists’ knowledge of and compliance with the Surviving Sepsis Campaign (SSC) guidelines in perioperative management patients sepsis China. designed a questionnaire-based, cross-sectional survey. sent out online questionnaires during 2019 evaluate whether anesthesiologists China were familiar applied SSC management. also compared among different levels hospital. In this study, we obtained 971 responses from anesthesiology departments across The survey showed...
Abstract Purpose Toothache, a common disorder afflicting most people, shows distinct features at different clinical stages. This study aimed to depict metabolic changes in brain and investigate the potential mechanism involved aberrant affective behaviors during natural process of toothache. Methods We investigated spatiotemporal patterns function course toothache rat model dental pulp injury (DPI) by using positron emission tomography (PET). Results Glucose metabolism peaked on 3 rd day...