A5035540627- Healthcare Systems and Technology
- Multiple Sclerosis Research Studies
- Primary Care and Health Outcomes
- Musculoskeletal Disorders and Rehabilitation
- Rheumatoid Arthritis Research and Therapies
- Health Systems, Economic Evaluations, Quality of Life
- Food Security and Health in Diverse Populations
- HIV, Drug Use, Sexual Risk
- Healthcare Policy and Management
- Cancer Cells and Metastasis
- Opioid Use Disorder Treatment
- Prostate Cancer Diagnosis and Treatment
- Orthopedic Infections and Treatments
- Hematopoietic Stem Cell Transplantation
- Gestational Diabetes Research and Management
- Patient Satisfaction in Healthcare
- Global Cancer Incidence and Screening
- Acute Lymphoblastic Leukemia research
- Diversity and Career in Medicine
- Orthopaedic implants and arthroplasty
- Economic and Financial Impacts of Cancer
- COVID-19 and healthcare impacts
- Total Knee Arthroplasty Outcomes
- Spine and Intervertebral Disc Pathology
- Innovations in Medical Education
Institute for Clinical Evaluative Sciences
2012-2025
Columbia University
2024
Northwell Health
2024
Hospital for Special Surgery
2024
Cornell University
2024
University of Toronto
2008-2023
St. Michael's Hospital
2016-2023
Health Solutions (Sweden)
2023
Women's College Hospital
2023
University of Waterloo
2018-2020
Importance Systemic treatments for psoriatic disease affect the immune system and may increase infection risk. Older adults are at high risk infection, relative safety of systemic them is unknown. Objective To evaluate association with rates serious among older adults. Design, Setting, Participants This cohort study used linked population-based health administrative data from 2002 to 2021 in Ontario, Canada. included Ontario residents 66 years who were dispensed their first medication...
Recommended by Heikki LehvaslaihoDue to rapid technological advances, various types of genomic and proteomic data with different sizes, formats, structures have become available.Among them are gene expression, single nucleotide polymorphism, copy number variation, proteinprotein/gene-gene interactions.Each these distinct provides a different, partly independent complementary, view the whole genome.However, understanding functions genes, proteins, other aspects genome requires more...
A retrospective cohort study.The aim of this study was to examine variation in spine surgery utilization between the province Ontario and state New York among all patients pre-specified patient subgroups.Spine is common costly. Within-country well studied, but there has been little exploration countries.We used population-level administrative data from (years 2011-2015) (2011-2014) identify adults who underwent inpatient spinal decompression or fusion using relevant procedure codes. Patients...
Capacitive sensors can be employed for measuring the electrocardiogram of a human heart without electric contact with skin. This configuration avoids problems experienced by conventional electrocardiography. In our studies, we integrated these capacitive electrodes in 15-sensor array and combined this tablet personal computer. By placing system on patient's body, measure 15-channel even through clothes any preparation. The goal development is to provide new diagnostic tool that offers user...
Background: A relationship between higher patient volume and both better quality of care outcomes has been shown for many acute conditions. Whether a volume–quality exists the outpatient management chronic diseases is uncertain. Objective: To explore association primary physician diabetes care. Design: Cohort study. Setting: The study was conducted using linked population-based health administrative data in Ontario, Canada. Patients: 1 018 647 adults with 2011 who received from 9014...
Rheumatology workforces are increasingly challenged by too few physicians in face of the growing burden rheumatic and musculoskeletal diseases (RMDs).Rheumatology is one most frequent non-surgical specialty referrals has longest wait times for subspecialists.We used a population-based approach to describe changes rheumatology workforce, patient volumes geographic variation supply access rheumatologists, Ontario, Canada, between 2000 2019, projected 2030.Over time, we observed greater...
Abstract Background Emergency department (ED) utilization is a significant concern in many countries, but few population‐based studies have compared ED use. Our objective was to compare New York (United States), Ontario (Canada), and Zealand (NZ). Methods A retrospective cross‐sectional analysis of all visits between January 1, 2016, September 30, 2017, for adults ≥18 years using data from the State Department Inpatient Databases (New York), National Ambulatory Care Reporting System...
The authors used a population-representative sample and health administrative data to quantify suicide-related behavior leading acute care or deaths across self-identified heterosexual, gay/lesbian, bisexual individuals.Data from population-based survey (N=123,995) were linked (2002-2019), differences in time events sexual orientations examined using Cox proportional hazards regression.The crude incidence rates of per 100,000 person-years 224.7 for heterosexuals, 664.7 gay/lesbian...
Total knee arthroplasty (TKA) and total hip (THA) are common effective surgical procedures. This study sought to compare utilization short-term outcomes of primary TKA THA in adjacent regions Canada the United States.The was designed as a retrospective cohort patients who underwent or THA, comparing administrative data from New York Ontario 2012-2013. Demographic features patients, per capita rates, were compared between jurisdictions.A higher percentage hospitals performed (75.7% versus...
<h3>Objective</h3> To validate a case definition of multiple sclerosis (MS) in the pediatric population using administrative (health claims) data, and to estimate incidence prevalence MS for Ontario, Canada. <h3>Methods</h3> We used population-based data identify persons aged ≤18 years with MS. assessed performance definitions clinical reference cohort including children MS, monophasic demyelinating syndromes, healthy children; we report sensitivity, specificity, positive predictive value...
Abstract Aim To compare perinatal outcomes in women with undiagnosed diabetes gestational alone, pre‐existing and without diabetes, to identify risk factors which distinguish them from alone. Methods This population‐based cohort study included administrative data on all who gave birth Ontario, Canada, during 2002–2015. Maternal/neonatal were compared across groups using logistic regression, adjusting for confounders. A nested case control type 2 alone determine that would help these women....
Induced-pluripotent stem cells (iPSCs) are a potential alternative cell source in regenerative medicine, which includes the use of differentiated iPSCs for therapies to treat coronary artery and/or peripheral arterial diseases. Late-outgrowth endothelial progenitor (late-EPCs) unique primary present blood that exhibit high proliferative capacity, being used wide variety clinical trials, and have ability differentiate into mature cells. The objective this study was reprogram blood-derived...
We aimed to compare health care utilization of children with pediatric-onset multiple sclerosis that age, sex and geographically-matched without sclerosis. Using population-based administrative data from Ontario, Canada for the period 2003–2014, we applied a validated case definition identify persons aged ≤18 years identified up 5 matched on sex, region residence. In each cohort, determined annual rates any hospitalization physician services use. general linear models compared adjusting...
We compared the prevalence of physical and mental conditions rate health care utilization in mothers children with multiple sclerosis (MS) (MS-mothers) that without MS (non-MS-mothers).Using population-based administrative data from Ontario, Canada, we identified MS-mothers non-MS-mothers, matched on maternal age at childbirth, region, child's sex time diagnosis. any condition or mood anxiety disorder between cohorts, diagnosis year, 5 years before after rates physician visits diagnosis,...
Objective. To compare differences in clinical activity and remuneration between male female rheumatologists to evaluate associations physician gender practice sizes patient volume, accounting for rheumatologists’ age, calendar year effects. Methods. We conducted a population-based study Ontario, Canada, 2000 2015 identifying all practicing as full-time equivalents (FTEs) or above assessed (number of unique patients), volumes visits), (total fee-for-service billings) rheumatologists....
Access to care varies between countries. It is theorized that income-based disparities in access may be reduced countries with universal health insurance relative the United States, but data are currently limited. We hypothesized differences total hip arthroplasty (THA) utilization and outcomes would larger States than Canada.
Abstract Aims To investigate the relationship between increasing parity and diabetes in a large, population‐based cohort, to examine if this is different among high‐risk ethnic groups. Methods A population‐based, retrospective cohort study was performed 738 440 women aged 18–50 years, who delivered babies Ontario 1 April 2002 31 March 2011. Diabetes incidence postpartum calculated for each group. multivariable analysis of effect ethnicity on using Cox proportional hazards model, adjusting...
Objective. To quantify population-level and practice-level encounters with rheumatologists over time. Methods. We conducted a population-based study from 2000 to 2015 in Ontario, Canada, where all residents are covered by single-payer healthcare system. Annual total number of unique patients seen rheumatologists, the new seen, were identified. Results. From 2015, percentage population was constant time (2.7%). During this time, Ontario had stable supply (0.8 full-time equivalents/75,000)....
Some jurisdictions restrict primary care physicians' daily patient volume to safeguard quality of for complex patients. Our objective was determine whether people with dementia receive lower-quality if their physician sees many patients daily.
Background: Studies of people who inject drugs (PWID) commonly use questionnaires to determine whether participants are currently, or have recently been, on opioid agonist treatment for disorder. However, these previously unvalidated self-reported measures may be susceptible inaccurate reporting. Methods: We linked baseline questionnaire data from 521 PWID in the Ontario integrated Supervised Injection Services cohort Toronto (November 2018–March 2020) with record-level health administrative...
Objective Allogeneic haematopoietic cell transplantation (HCT) is a potentially curative treatment for haematologic and oncologic diseases. There perception that the United States of America (USA) offers greater access to expensive therapies such as HCT. Alternatively, Canada thought suffer from protracted wait times, but lower spending. Our objective was compare HCT utilisation short-term outcomes in Ontario (ON), Canada, New York State (NY), USA. Design, setting participants We conducted...