Luigi Vernaglione

ORCID: 0000-0001-5303-355X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Dialysis and Renal Disease Management
  • Central Venous Catheters and Hemodialysis
  • Parathyroid Disorders and Treatments
  • Muscle and Compartmental Disorders
  • Blood Pressure and Hypertension Studies
  • Body Composition Measurement Techniques
  • Hemodynamic Monitoring and Therapy
  • Renal function and acid-base balance
  • Chronic Kidney Disease and Diabetes
  • Pharmacological Effects and Toxicity Studies
  • Vascular Procedures and Complications
  • Lipoproteins and Cardiovascular Health
  • Genetic Syndromes and Imprinting
  • Electrical and Bioimpedance Tomography
  • Vaccine Coverage and Hesitancy
  • Renal and Vascular Pathologies
  • Neurological and metabolic disorders
  • Vitamin D Research Studies
  • Metabolism and Genetic Disorders
  • Magnesium in Health and Disease
  • Mechanical Circulatory Support Devices
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Climate Change and Health Impacts
  • Bone health and treatments

Ospedale A. Perrino
2014-2024

Razi Hospital
2008

Ospedale Generale Regionale Francesco Miulli
2006

University of Bari Aldo Moro
1998

Background. Satisfactory haemodialysis (HD) vascular access flow (Qa) is necessary for dialysis adequacy. High Qa postulated to increase cardiac output (CO) and cause high-output failure. Aim of the present prospective study was evaluate relationship between arteriovenous fistulas (AVFs) CO in order have a closer insight into this scarcely explored aspect HD pathophysiology. Methods. Ninety-six patients bearing an AVF entered study. All were evaluated priori existence failure according...

10.1093/ndt/gfm549 article EN Nephrology Dialysis Transplantation 2007-08-17

Background. Several studies already stressed the importance of haemodialysis (HD) time in removal uraemic toxins. In those studies, however, also amount dialysate and/or processed blood was altered. The present study aimed to investigate isolated effect factor t (by processing same total and volume two different schedules) on kinetic behaviour some small, middle protein-bound molecules.

10.1093/ndt/gfq543 article EN Nephrology Dialysis Transplantation 2010-09-02

Pregnancy in women with chronic kidney disease has always been considered as a challenging event both for the mother and fetus. Over years, several improvements have achieved outcome of pregnant renal patients increasing rates successful deliveries. To date, evidence suggests that stage failure is main predictive factor worsening residual function complications women. Moreover, possibility success pregnancy depends on adequate depurative pharmacological strategies end-stage disease. In this...

10.1093/ckj/sfv016 article EN cc-by-nc Clinical Kidney Journal 2015-03-19

ABSTRACT Background The known risks and benefits of native kidney biopsies are mainly based on the findings retrospective studies. aim this multicentre prospective study was to evaluate safety percutaneous renal quantify biopsy-related complication rates in Italy. Methods examined results performed 54 Italian nephrology centres between 2012 2020. primary outcome rate major complications 1 day after procedure, or for longer if it necessary evolution a complication. Centre patient risk...

10.1093/ndt/gfac177 article EN cc-by-nc Nephrology Dialysis Transplantation 2022-05-19

Background. Hypovolaemia has been implicated as a major causal factor of morbidity during haemodialysis (HD). A model biofeedback control system for intra‐HD blood volume (BV) changes modelling developed (Hemocontrol™, Hospal Italy) to prevent destabilizing hypovolaemia. It is based on an adaptive controller incorporated in HD machine (Integra™, Italy). The Hemocontrol™ (HBS) monitors BV contraction with optical device. HBS modulates rates by adjusting the ultrafiltration rate (UFR) and...

10.1093/ndt/16.2.328 article EN Nephrology Dialysis Transplantation 2001-02-01

Data on exercise activities in place, and the interest for developing them Nephrology Services Italy is limited. To address this gap, we carried out cross-sectional study to investigate status of physical activity programs available Italian Centres. Additionally, research priorities topic were examined. We developed a 14-item electronic survey, which consisted multiple-choice questions covering training programs, assessment, barriers practice counselling practices, perceived benefits,...

10.1007/s40620-024-01896-w article EN cc-by Journal of Nephrology 2024-03-06

Accurate assessment of hydration status and specification dry weight (DW) are major problems in the clinical treatment hemodialysis (HD) patients. Bioelectrical impedance analysis (BIA) has been recognized as a noninvasive simple technique for determination DW HD patients.This study was designed to develop validate BIA prediction equations It included white adults (1540 disease-free with normal body mass index [BMI] 456 prevalent 27 incident patients). All participants underwent at least one...

10.2215/cjn.00240107 article EN Clinical Journal of the American Society of Nephrology 2007-05-19

Vitamin D receptor activation by vitamin sterols and calcium-sensing stimulation cinacalcet are the most powerful treatments of secondary hyperparathyroidism. This study was aimed to assess a possible association between histopathologic changes parathyroid tissue treatment modality.Studies were performed on 82 parathyroids 22 adult white hemodialysis patients undergoing first parathyroidectomy. The type hyperplasia distribution chief oxyphil cells, expressed as oxyphil/chief cell ratio,...

10.2215/cjn.04150907 article EN Clinical Journal of the American Society of Nephrology 2008-03-06

Satisfactory vascular access flow (Qa) of an arteriovenous fistula (AVF) is necessary for haemodialysis (HD) adequacy. The aim the present study was to further our understanding haemodynamic modifications cardiovascular system HD patients associated with AVF. main objective calculate using real data in what way AVF influences load left ventricle (LLV). All treated dialysis unit and bearing were enrolled into observational cross-sectional study. Fifty-six bore a lower arm 30 upper Qa cardiac...

10.1093/ckj/sfw063 article EN cc-by-nc Clinical Kidney Journal 2016-07-15

Background. Clinical practice guidelines have supported vascular access surveillance programmes on the premise that natural history of will be altered by radiological or surgical interventions after dysfunction is detected. The primary objective this study was to assess actual risk thrombosis autogenous radio-cephalic (RC) wrist arteriovenous fistulas (AVFs) without any pre-emptive interventions.

10.1093/ndt/gfh073 article EN Nephrology Dialysis Transplantation 2004-02-19

One of the most important pathogenetic factors involved in onset intradialysis arrhytmias is alteration electrolyte concentration, particularly potassium (K(+)).Two studies were performed: Study A was designed to investigate above all isolated effect factor time t on K(+) mass balance (K(+)MB): 11 stable prevalent Caucasian anuric patients underwent one standard (∼4 h) and long-hour (∼8 bicarbonate haemodialysis (HD) session. The latter pair-matched as far dialysate blood volume processed...

10.1093/ndt/gfu376 article EN Nephrology Dialysis Transplantation 2014-12-13

Background.Kt/Vurea was established as an index of haemodialysis (HD) adequacy. The use Vurea a normalizing factor has been questioned, and alternative parameters such body weight0.67 (W0.67), surface area (BSA), resting energy expenditure (REE), high metabolic rate organ (HMRO) mass, liver size (LV) more recently, bioelectrical resistance (R), independent directly measurable biological parameter, were proposed methods for scaling dialysis dose. Methods. present study aimed to prospectively...

10.1093/ndt/gfp603 article EN Nephrology Dialysis Transplantation 2009-12-08

Background. The accurate measurement of total body water (TBW) requires isotopic dilution techniques that are not easily applicable to the clinical setting. Therefore, indirect methods estimating TBW commonly employed, such as bioelectrical impedance analysis (BIA) and anthropometry. In human body, >90% measured is composed resistance ( R ).

10.1093/ndt/gfm909 article EN Nephrology Dialysis Transplantation 2008-01-22

Background. A persistent hyperphosphataemia represents one of the most important factors in development secondary hyperparathyroidism (sHPTH). The present prospective study was designed order to test hypothesis that a higher body mass index (BMI) may predispose larger burden phosphate (P), influencing by way severity sHPTH.

10.1093/ndt/gfi311 article EN Nephrology Dialysis Transplantation 2005-12-02

Abstract Background Peripheral artery disease (PAD) in hemodialysis (HD) patients has a significant social impact due to its prevalence, poor response standard therapy and dismal prognosis. Rheopheresis is indicated by guidelines for PAD treatment. Materials Methods Twenty‐five HD affected stage IV Lerichè‐Fontaine ischemic ulcer 1C or 2C according the University of Texas Wound Classification System ( UTWCS ), without amelioration after traditional medical and/or revascularization, were...

10.1002/jca.22132 article EN cc-by-nc-nd Journal of Clinical Apheresis 2024-08-01

Background. The interplay of correct solute mass balances, such as that sodium (Na+) and potassium (K+) (respectively, Na+MB K+MB) with adequate ultrafiltration volumes (VUF), is crucial in order to achieve haemodynamic stability during haemodialysis (HD). GENIUS single-pass batch dialysis system (Fresenius Medical Care, Germany) consists a closed dialysate tank 90 L; it offers the unique opportunity effecting balances any very precise way.

10.1093/ndt/gfq351 article EN Nephrology Dialysis Transplantation 2010-06-22
Coming Soon ...