A5021790551- Autism Spectrum Disorder Research
- Regulation of Appetite and Obesity
- Eating Disorders and Behaviors
- Genetics and Neurodevelopmental Disorders
- Neurotransmitter Receptor Influence on Behavior
- Adipose Tissue and Metabolism
- Child Nutrition and Feeding Issues
- Child Development and Digital Technology
- Receptor Mechanisms and Signaling
- Genetic Associations and Epidemiology
- Obesity, Physical Activity, Diet
- Pancreatic function and diabetes
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Physical Performance
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Birth, Development, and Health
- Animal testing and alternatives
- Blood properties and coagulation
- Neurogenesis and neuroplasticity mechanisms
- Muscle Physiology and Disorders
- Bipolar Disorder and Treatment
- Biochemical and Molecular Research
- Genomic variations and chromosomal abnormalities
- Breastfeeding Practices and Influences
Karolinska Institutet
2015-2022
Utrecht University
2013-2020
University Medical Center Utrecht
2009-2017
Maj Institute of Pharmacology
2010
Polish Academy of Sciences
2009-2010
University of Łódź
1988
The substantial phenotypic heterogeneity in autism limits our understanding of its genetic etiology. To address this gap, here we investigated differences between autistic individuals (n
Abstract Background Various drugs of abuse activate intracellular pathways in the brain reward system. These regulate expression genes that are essential to development addiction. To reveal common and distinct for different classes abuse, we compared effects nicotine, ethanol, cocaine, morphine, heroin methamphetamine on gene profiles mouse striatum. Results We applied whole-genome microarray profiling evaluate detailed time-courses (1, 2, 4 8 hours) transcriptome alterations following acute...
Abstract. Europe is diverse in terms of economy, cultures, socio-demography, and languages. A crucial aspect psychiatric research the availability standardized screening, diagnostic, characterization instruments. We fine-mapped accessibility 14 clinical scales cognitive tests for assessment early childhood Autism Spectrum Disorder (ASD; e.g., ADOS, ADI-R, SCQ, SRS, CHAT, MESL) within 21 European countries. These tools are essential internationally competitive ASD detection research....
ObjectivePatients with anorexia nervosa (AN) are often observed to have high levels of physical activity, which do not necessarily diminish after a successful therapy. Previous studies shown that body fat tissue recovery in these patients is associated disproportional restoration the adipocyte hormone, leptin. Therefore, we wondered whether individual variation activity AN prior treatment may be related percentage and plasma leptin level outcome. MethodBody percentage, serum, (accelerometer)...
Abstract The environmental contributions to autism spectrum disorder (ASD) and their informative content for diagnosing the condition are still largely unknown. objective of this study was investigate associations between early medical events ASD, as well autistic traits, in twins, test hypothesis a cumulative effect on ASD risk. A total 80 monozygotic (MZ) twin pairs (including rare sample 13 discordant clinical ASD) 46 dizygotic (DZ) with varying were examined intra-pair differences (for...
Abstract Background Current policies regulating the use of animals for scientific purposes are based on balancing between potential gain knowledge and suffering used in experimentation. The process is complicated, one hand by plurality views our duties towards animals, other more recent discussions uncertainty probability reaching final aim research problems translational failure. Methods study combines ethical analysis a literature review with neuropsychiatry-related preclinical as case...