A5062160642- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nosocomial Infections in ICU
- Urinary Tract Infections Management
- Pharmaceutical studies and practices
- Mechanical Circulatory Support Devices
- Pharmacological Effects and Toxicity Studies
- COVID-19 and healthcare impacts
- Sports injuries and prevention
- Tuberculosis Research and Epidemiology
- Drug-Induced Adverse Reactions
- Hearing Impairment and Communication
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Viral gastroenteritis research and epidemiology
- Infective Endocarditis Diagnosis and Management
- Child Nutrition and Feeding Issues
Northwestern Memorial Hospital
2020-2025
Northwestern Medicine
2019-2025
Brooke Army Medical Center
2024
Midwestern University
2020
University of Georgia
2019
Augusta University
2011
University of Colorado Denver
2010
University of Bristol
1981-1985
Institute of Child Health
1982
Central Middlesex Hospital
1978-1979
This is a summary of report which was the result an epidemiological investigation, carried out under sponsorship Commission for European Communities (CEC) and its Committee on Medical Public Health Research (CRM) in nine countries Community, order to determine prevalence childhood deafness. The design study specified that all children born during year 1969 would be included if their hearing loss averaged 50 dB or worse better ear. Most were enumerated 1977 when they eight years old.The...
Coronavirus disease 2019 (COVID-19) has strained healthcare systems with patient hospitalizations and deaths. Anti-spike monoclonal antibodies, including bamlanivimab, have demonstrated reduction in hospitalization rates clinical trials, yet real-world evidence is lacking.We conducted a retrospective case-control study across single system of nonhospitalized patients, age 18 years or older, documented positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing, risk factors...
The clinical, epidemiological, and virological features of an outbreak winter vomiting disease among London schoolchildren are described. Evidence is presented to support the view that this epidemic was caused by a human calicivirus, virus not previously shown be associated with in man.
Abstract Background The escalating prevalence of multidrug-resistant (MDR) Pseudomonas aeruginosa presents a serious threat to patient care due its limited treatment options. However, imipenem-cilastatin-relebactam (IMI/REL) is promising beta-lactam/beta-lactamase inhibitor combination with expanded activity against MDR P. aeruginosa. This study aimed explore the characteristics, efficacy and safety IMI/REL for infections aeruginosa.Table 1.Patient infection characteristics. Methods was...
Abstract Background Candida auris is a yeast that causes invasive infections such as bloodstream (BSIs); mortality rates for C. BSIs may be high 80%. Rates have been climbing in the U.S. Exposure to skilled nursing facilities (SNFs), long-term acute care hospitals (LTACHs), or inpatient rehabilitation (IRFs) represents known risk factor auris. Our institution experienced outbreak from September 2023 - January 2024. Figure 1: Outbreak Epidemic Curve Methods cases were identified clinical...
Abstract Background Urinary tract infections (UTIs) are one of the common reasons for antibiotic use across healthcare settings. Across an eleven-hospital system, urinary pathogens (E. coli, Proteus species, and Klebsiella species) had greater than 80% coverage with cefazolin, which was within 0-8% ceftriaxone based on local antibiograms. With increased risk C. difficile infection resistance development seen ceftriaxone, cefazolin promoted as first line empiric UTI coverage.Table 1:Outcomes...
Abstract Background Urinary tract infections (UTIs) are the most common bacterial infections, yet patients with recurrent infection often not offered effective preventative therapies, persistence may have a urologic nidus of infection, and non-infectious syndromes over-treated antibiotics. Methods We developed Complex Urologic Infections Interdisciplinary Clinic comprised infectious diseases urology physicians as well antimicrobial stewardship pharmacists. categorized complicated (defined...
Abstract Background Obtaining data has been an ongoing challenge for antimicrobial stewardship programs. With the creation and recent update of Joint Commission standards, increased focus placed on acting relevant to improve use. We describe development use a systemwide dashboard help track meaningful outcomes identify areas opportunity our Antimicrobial Diagnostic Stewardship Program (ADSP). Methods A list all potential pieces we may want be able compare was made, including demographic...
Abstract Background Multidrug-resistant (MDR) Gram-negative infections are a substantial threat to patients and public health. Imipenem/cilastatin/relebactam (IMI/REL) is beta-lactam/beta-lactamase inhibitor with expanded activity against MDR Pseudomonas aeruginosa carbapenem-resistant Enterobacterales. This study aims describe the patient characteristics, prescribing patterns, clinical outcomes associated IMI/REL. Methods was retrospective, multicenter, observational of ≥18 years old who...
An attempted controlled trial of exclusively breast fed neonates with atopic parents, to assess the effectiveness feeding in preventing allergy, was not successfully achieved. Analysis data as an observational study, however, provided evidence that offers some protection against eczema genetically vulnerable infants. Feeds soya preparations were associated often cows9 milk based feeds.
High hamstring tendinopathy is an uncommon overuse injury seen in running athletes. Patients typically report deep buttock or thigh pain. A detailed physical examination and, occasionally, imaging studies are necessary to confirm the diagnosis. Rehabilitation involves soft-tissue mobilization, frequent stretching, and progressive eccentric strengthening core stabilization exercises. In recalcitrant cases, ultrasound-guided corticosteroid injection into tendon sheath can be helpful, surgery...
Abstract A multicenter case series of 21 patients were treated with imipenem-cilastatin-relebactam. There mixed infection sources, pulmonary infections (11/21,52%) composing the majority. The primary pathogen was Pseudomonas aeruginosa (16/21, 76%), and 15/16 (94%) isolates multidrug-resistant. Thirty-day survival occurred in 14/21 (67%) patients. Two experienced adverse effects.
Abstract Background Vancomycin (VAN)-associated acute kidney injury (AKI) is increased when VAN combined with certain beta-lactams (BLs) such as piperacillin-tazobactam (TZP) but has not been evaluated ceftolozane-tazobactam (C/T). Our aim was to investigate the AKI incidence of in combination C/T (VAN/C/T) compared TZP (VAN-TZP). Methods We conducted a multicenter, observational, comparative study across United States. The primary analysis composite outcome and risk, injury, failure, loss,...
The coronavirus disease 2019 (COVID-19) pandemic has impacted the activities of healthcare workers, including postgraduate pharmacy trainees. Quality training experiences must be maintained to produce competent practitioners and maintain program standards.A cross-sectional survey trainees in United States was conducted evaluate experience changes assess perceived impacts on residents fellows following COVID-19 pandemic's onset.From June 4 through 22, 2020, 511 46 states completed survey....