A5058295408- Air Quality and Health Impacts
- Toxic Organic Pollutants Impact
- Health, Environment, Cognitive Aging
- Effects and risks of endocrine disrupting chemicals
- Testicular diseases and treatments
- Carcinogens and Genotoxicity Assessment
- Nutritional Studies and Diet
- Air Quality Monitoring and Forecasting
- Heavy Metal Exposure and Toxicity
- Bariatric Surgery and Outcomes
- Asthma and respiratory diseases
- Renal and related cancers
- Cancer Risks and Factors
- Vehicle emissions and performance
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Gastrointestinal Tumor Research and Treatment
- Multiple Sclerosis Research Studies
- Chronic Lymphocytic Leukemia Research
- Peripheral Neuropathies and Disorders
- Sperm and Testicular Function
- Atmospheric chemistry and aerosols
- Healthcare Systems and Practices
- Lymphoma Diagnosis and Treatment
- Climate Change and Health Impacts
- Health Systems, Economic Evaluations, Quality of Life
École de management de Lyon
2024-2025
Centre Léon Bérard
2021-2024
Inserm
2021-2024
Université Claude Bernard Lyon 1
2022-2024
Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement
2022-2024
Centre de Recherche en Cancérologie de Lyon
2021
Université de Bordeaux
2019
Benzo[a]pyrene (BaP) is an endocrine-disrupting pollutant formed during incomplete combustion of organic materials. It has been recognized as a reproductive and developmental toxicant, however epidemiological evidence the long-term effect ambient air BaP on breast cancer (BC) limited. Thus we evaluated associations between exposure risk BC, overall according to menopausal status molecular subtypes (estrogen receptor negative/positive (ER−/ER+) progesterone (PR−/PR+)), stage grade...
Nitrogen dioxide (NO2) is an important air pollutant due to its adverse effects on human health. Yet, current evidence the association between NO2 and risk of breast cancer lacks consistency. In this study, we investigated long-term exposure in French E3N cohort study. Association with was assessed a nested case-control study within including 5222 cases identified over 1990-2011 follow-up period matched controls. Annual mean concentrations at participants' residential addresses for each year...
Background Testicular germ cell tumors (TGCT) are the most frequent cancer in young men developed countries. Parental occupational exposures during early-life periods suspected to increase TGCT risk. The objective was estimate association between parental occupations at birth and adult TGCT. Methods A case–control study conducted, including 454 cases aged 18–45 from 20 French university hospitals, matched 670 controls based on region year of birth. Data collected participants included jobs...
Objective Testicular germ cell tumours (TGCT) are the most common cancer in men of working age and its incidence has increased notably over past 40 years. Several occupations have been identified as potentially associated with TGCT risk. The aim this study was to further explore relationship between occupations, industries risk aged 18–45 Methods TESTIS is a multicenter case–control conducted January 2015 April 2018 20 23 university hospital centers metropolitan France. A total 454 cases 670...
Abstract Molecular studies suggest that cadmium due to its estrogenic properties, might play a role in breast cancer (BC) progression. However epidemiological evidence is limited. This study explored the association between long-term exposure airborne and risk of BC by stage, grade differentiation, histological types at diagnosis. A nested case–control 4401 cases matched controls was conducted within French E3N cohort. Geographic Information System (GIS)-based metric demonstrated reliably...
<title>Abstract</title> <bold>Background:</bold> While genetic, hormonal, and lifestyle factors partially elucidate the incidence of breast cancer, emerging research has underscored potential contribution air pollution. Polychlorinated biphenyls (PCBs) benzo[a]pyrene (BaP), are particular concern due to endocrine-disrupting properties, accumulation in various environmental matrices human adipose tissue owing poor biodegradability. <bold>Objective:</bold> To identify distinct lifetime...
L'étude Olidia est issue d'un chaînage entre l'étude clinique de Phase IV PRO-MSactive, qui avait pour objectif d'évaluer l'efficacité d'ocrelizumab dans les formes actives sclérose en plaques (SEP), et données du SNDS. L'objectif était mettre commun informations contenues deux sources afin décrire traitements reçus cinq ans la consommation soins avant mise sous ocrelizumab, chez patients atteints d'une forme récurrente-rémittente (SEP-RR) ou secondairement progressive (SEP-SP) SEP. Tous...
Abstract Background Ibrutinib is a Bruton’s tyrosine kinase inhibitor indicated for the first-line treatment and relapse of chronic lymphocytic leukaemia (CLL), Waldenström’s macroglobulinemia (WM) mantle cell lymphoma (MCL). This study aimed to describe characteristics CLL patients treated with ibrutinib its effectiveness, safety, pattern in real life. Methods All covered by general health scheme (approximately 80% French population) first dispensation from August 1, 2017 (date...
BACKGROUND AND AIM. Testicular germ cell tumors (TGCT) are the most frequently diagnosed cancer in young men and their incidence rate has increased dramatically recent decades. Occupational factors may play a role testicular etiology. This study aimed to further explore association between occupation, industry, risk of TGCT adulthood France. METHODS. The TESTIS included 454 histologically confirmed cases at ages 18-45 years. Controls (N=670) were frequency-matched on 5-year age group region....
BACKGROUND AND AIM: Benzo[a]pyrene (BaP) is an endocrine-disrupting pollutant formed during incomplete combustion of organic materials. It has been recognized as a reproductive toxicant, however epidemiological evidence its long-term effect on breast cancer (BC) limited. Thus we evaluated associations between ambient air BaP exposure and risk BC, overall according to menopausal status molecular subtypes (estrogen receptor negative/positive (ER-/ER+) progesterone (PR-/PR+)), stage grade...
BACKGROUND AND AIM: Nitrogen dioxide (NO2) is one of an important air pollutant due to its adverse effects on human health, however whether it consistently associated with the risk breast cancer (BC) limited. In this study, we investigated association between long term exposure NO2 and BC. METHODS: A total 5,222 BC cases identified over follow up period matched controls a nested case-control study within French E3N cohort were examined. Mean estimates estimated by CHIMERE land use regression...
BACKGROUND AND AIM: Although the genetic and hormonal risk factors of breast cancer are well identified, they cannot fully explain occurrence all cases. Epidemiological experimental studies have suggested that exposure to environmental pollutants, especially those with potential estrogenic properties, as polychlorinated biphenyls (PCBs) may a role in development. We aimed estimate association between cumulative atmospheric PCB153 risk. METHODS: conducted case-control study 5,222 cases...
Abstract Purpose Molecular and cellular studies reported a role of cadmium in risk advanced breast cancer (BC). However epidemiological evidence is limited. Our previous study suggests that might be related to decreased ER- ER-PR- tumors. In this study, we further explored the association between long-term exposure airborne BC by stage, grade differentiation, histological types at diagnosis. Methods A nested case-control 4,401 cases matched controls was conducted within French E3N cohort....