A5018082621- Natural product bioactivities and synthesis
- Ginseng Biological Effects and Applications
- Phytochemistry and Biological Activities
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Virology and Viral Diseases
- Hepatitis Viruses Studies and Epidemiology
- Mosquito-borne diseases and control
- Hepatitis C virus research
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Respiratory viral infections research
- Phytochemical Studies and Bioactivities
- Traditional Chinese Medicine Studies
- Vaccine Coverage and Hesitancy
- Herpesvirus Infections and Treatments
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- Metabolomics and Mass Spectrometry Studies
- Medicinal Plants and Bioactive Compounds
- Biochemical effects in animals
- NF-κB Signaling Pathways
Shenyang Pharmaceutical University
2016-2025
Gansu Provincial Center for Disease Control and Prevention
2014-2024
Xinxiang University
2024
Second Affiliated Hospital of Guangzhou Medical University
2024
Guangzhou Medical University
2024
Gansu University of Traditional Chinese Medicine
2024
Wuhan University of Technology
2024
Binzhou University
2011-2020
Nanjing Normal University
2019-2020
Binzhou Medical University
2016-2020
As one class of important functional materials, transition metal phosphides (TMPs) nanostructures show promising applications in catalysis and energy storage fields. Although great progress has been achieved, phase-controlled synthesis cobalt nanocrystals or related nanohybrids remains a challenge, their use overall water splitting (OWS) is not systematically studied. Herein, three kinds encapsulated by P-doped carbon (PC) married with graphene (PG) nanohybrids, including CoP@PC/PG, CoP-Co2...
To investigate the HPV vaccine coverage and post-vaccination adverse reactions in Gansu Province, Western China, from 2018 to 2021. Data on suspected vaccines were collected Chinese Vaccine Adverse Event Following Immunization (AEFI). Estimate incidence rates of Common Reaction Rare Reaction. among females different age groups was calculated using data Provincial Information Platform. The first-dose rate aged 9 45 2.02%, with lowest less than 1% observed 14. From 2021, reported after...
Two-dimensional transition metal oxyhydroxide (MOOH) nanostructures show great potential for application in catalysis, sensing, secondary batteries, and supercapacitors fields. Nonetheless, it is still a challenge to orient hybridize MOOH nanosheets with carbon-free conductive materials (e.g., CuSe), their uses flexible in-plane asymmetric microsupercapacitors (AMSCs) are not explored. Herein, vertically oriented CuSe@FeOOH CuSe@MnOOH hybrid nanosheet frameworks alternately integrated on Au...
Background Mosquitoes host and transmit numerous arthropod-borne viruses (arboviruses) that cause disease in both humans animals. Effective surveillance of virome profiles mosquitoes is vital to the prevention control mosquito-borne diseases northwestern China, where epidemics occur frequently. Methods were collected Shaanxi-Gansu-Ningxia region (Shaanxi Province, Gansu Ningxia Hui Autonomous Region) China from June August 2019. Morphological methods used for taxonomic identification...
The flowers of Callistephus chinensis (L.) Nees, the only species in genus within family Asteraceae, exhibit various pharmacological activities. From ethanol extract, two compounds were identified: a known compound named callistephus A and new derivative, G. Their structures elucidated through 1D-NMR, 2D-NMR mass spectrometry. In addition, we also evaluated anti-hepatic fibrosis activity G, showing that G can markedly suppress growth LX-2 cells induced by TGF-β1 at concentrations 1-6 μM....
We conducted a follow-up survey for 55 Japanese encephalitis (JE) cases 1–2 years after hospital discharge in Gansu province, China. Community-, education-, and gender-matched healthy individuals without history of neurologic disease were selected as the comparison group. All subjects received neurological examination, intelligence quotient (IQ) measurement, adaptive behavior Wechsler memory scale (WMS) assessment. found 43.6% JE had at least one nervous system sequelae compared with 3.6%...
Cervical cancer is the third most common and fourth leading cause of malignancy related mortality in women worldwide. CCL19 highly expressed human cells, ligand binding to CCR7 induces actin polymerization pseudopodia formation. However, whether or not involved EMT cervical needs further investigation. Using quantitative PCR western blot analyses, we found that overexpressed cell lines tissues. Knockdown via siRNA inhibited proliferation cells by increasing apoptosis. Further analyses showed...
Acorn leaves, which possess potential pharmacologic effects, are traditionally consumed as food in China. Phytochemical investigations of acorn leaves yielded one new and 25 known polyphenols, their structures were identified by extensive spectroscopic analysis. Three antidiabetes assays conducted. Compound 2 considerably increased the survival pancreatic beta cells reducing production reactive oxygen species enhancing activities superoxide dismutase, catalase, glutathione MIN6 damaged H2O2....
A sensitive and reliable ultra high performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry method was established to separate identify the chemical constituents of Zhi–Zi–Da–Huang decoction, a classic traditional Chinese medicine formula. The chromatographic separation achieved on Shim‐pack XR‐ODS C 18 column (75 × 3.0 mm, 2.2 μm) using gradient elution program. detection performed Waters Xevo G2 Q‐TOF spectrometer equipped electrospray ionization source...
Background A measles outbreak occurred in a western county of China 2013, the year after China's historic nadir measles. We conducted field investigation to identify gaps vaccination coverage and immunization program weaknesses, provide recommendations for response improvement. Methods analyzed surveillance data from 2008 2013 describe epidemiology county. Measles-containing vaccine was estimated using two methods: previously-reported administrative an estimation by clinic-kept records (n =...
Myocardial fibrosis (MF) is a common pathological feature of many heart diseases and seriously threatens the normal activity heart. Jiaogulan (Gynostemma pentaphyllum) tea functional food that commercially available worldwide. Gypensapogenin I (Gyp I), which novel dammarane-type saponin, was obtained from hydrolysates total gypenosides. It has been reported to exert beneficial anti-inflammatory effect. In our study, we attempted investigate efficiency possible molecular mechanism Gyp in...