Donghua Li

ORCID: 0000-0002-9122-9833
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About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Uterine Myomas and Treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Endometriosis Research and Treatment
  • COVID-19 epidemiological studies
  • Neurological Disorders and Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Zoonotic diseases and public health
  • Gallbladder and Bile Duct Disorders
  • Pancreatitis Pathology and Treatment
  • Colorectal and Anal Carcinomas
  • Sperm and Testicular Function
  • Genetic and phenotypic traits in livestock
  • Air Quality and Health Impacts
  • Reproductive System and Pregnancy
  • MicroRNA in disease regulation
  • Gastric Cancer Management and Outcomes
  • Fatty Acid Research and Health
  • Ideological and Political Education
  • Mosquito-borne diseases and control
  • Traditional Chinese Medicine Studies
  • Liver Disease Diagnosis and Treatment
  • Livestock and Poultry Management
  • Ovarian cancer diagnosis and treatment
  • Gastrointestinal motility and disorders

Lanzhou University
2022-2025

Gansu Provincial Maternal and Child Health Hospital
2025

Capital Medical University
2012-2024

Panzhihua Central Hospital
2024

Henan Agricultural University
2020-2024

Tianjin Nankai Hospital
2006-2023

University of South China
2022

Jiangsu Province Hospital
2021

Nanjing Medical University
2010-2021

Capital University
2005-2021

Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction members of the LDL receptor family. ApoE exists as three common isoforms that have important distinct functional biological properties. Two apoE isoforms, apoE3 apoE4, are recognized by receptor, whereas apoE2 binds poorly to this is associated type III hyperlipidemia. In addition, apoE4 isoform late-onset familial sporadic forms Alzheimer's disease. Although well characterized, specificity other family for...

10.1194/jlr.m500114-jlr200 article EN cc-by Journal of Lipid Research 2005-05-02

Purpose The purpose of this paper is to examine the roles four distinct but related aspects psychological capital – optimism, hope, self-efficacy and resilience in facilitating employee creativity. Drawing on perspective creativity literature, we propose that optimism hope increase resilience, which benefits Moreover, authors hypothesize have mediating context, which, turn, has a positive effect individual employees’ Design/methodology/approach Data were obtained from survey multiple...

10.1108/cdi-04-2018-0103 article EN Career Development International 2019-06-19

To study the effects of supplementation a marine omega-3 poly-unsaturated fatty acids (n3-PUFA) formulation (Omega3Q10) in older adults with hypertension and/or hypercholesterolemia. A total 97 people were enrolled to receive 12-week either Omega3Q10 (n = 48) or soybean oil 49). Total cholesterol (TC), low density lipoprotein (LDL-C), high (HDL-C), and hypertension-related symptoms determined before after supplementation. There no baseline differences between two groups. significantly...

10.1186/s12944-017-0617-0 article EN cc-by Lipids in Health and Disease 2017-12-01

The "KNDy neurons" located in the hypothalamic arcuate nucleus (ARC) of mammals are known to co-express kisspeptin, neurokinin B (NKB), and dynorphin (DYN), have been identified as key mediators feedback regulation steroid hormones on gonadotropin-releasing hormone (GnRH). However, birds, genes encoding kisspeptin its receptor GPR54 genomic lost, leaving unclear mechanisms for GnRH by hormones. Here, tachykinin 3 (TAC3) prodynorphin (PDYN) chicken NKB DYN neuropeptides were successfully...

10.1016/j.psj.2024.103820 article EN cc-by-nc-nd Poultry Science 2024-05-06

significantly ameliorated by pretreatment with GdCl3 and KCs play a vital role in AHNP-LI.

10.3748/wjg.v12.i3.403 article EN cc-by-nc World Journal of Gastroenterology 2006-01-01

Intestinal obstruction is a common disease requiring abdominal surgery with significant morbidity and mortality. Currently, an effective medical treatment for obstruction, other than surgical resection or decompression, does not exist. Si-Jun-Zi Decoction famous Chinese medicine used to replenish qi invigorate the functions of spleen. Modern pharmacological studies show that this prescription can improve gastrointestinal function strengthen immune function. In study, we investigated effects...

10.1155/2014/928579 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01

To evaluate the clinical safety and efficacies of percutaneous vertebroplasty (PVP), kyphoplasty (PKP), mesh-container-plasty (PMCP) for treatment vertebral compression fractures (VCFs), a retrospective study 90 patients with VCFs who had been treated by PVP (n = 30), PKP PMCP 30) was conducted. The these three treatments were evaluated comparing their PMMA cement leakages, patterns, height restoration percentages, wedge angles, visual analogue scales (VAS), oswestry disability index (ODI)...

10.1371/journal.pone.0151492 article EN cc-by PLoS ONE 2016-03-10

The reproductive performance of breeder roosters has significant economic importance in the poultry industry. Breeder have severely reduced semen quality with age and will be at risk culling following years. In order to extend use roosters, we drew on induced molting model hens selected 35 Houdan aged 50 wk for molting. By comparing body weight, testicular quality, before after molting, found that could restore weight levels (P > 0.05). At same time, it significantly improved sperm motility...

10.1016/j.psj.2023.102935 article EN cc-by-nc-nd Poultry Science 2023-07-13

Abstract Background From January 2020 to December 2022, China implemented “First-level-response”, “Normalized-control” and “Dynamic-COVID-zero” block the COVID-19 epidemic; however, immediate long-term impact of three strategies on other infectious diseases difference in their is currently unknown. We aim provide a more comprehensive understanding non-pharmacological interventions (NPIs) China. Methods collected data monthly case count from 2015 July 2022. After considering trends using...

10.1186/s12889-023-16318-y article EN cc-by BMC Public Health 2023-07-18

To investigate structural and quantitative alterations of gut microbiota in an experimental model small bowel obstruction.A rat obstruction was established by using a polyvinyl chloride ring surgically placed surrounding the terminal ileum. The were studied after intestinal obstruction. Intraluminal fecal samples proximal to collected at different time points (24, 48 72 hours obstruction) analyzed 16s rDNA high-throughput sequencing technology PCR (qPCR) for target bacterial groups....

10.1371/journal.pone.0255651 article EN cc-by PLoS ONE 2021-08-04

The reproductive performance of chicken breeders has significant economic importance in the poultry industry, and sperm motility is an indicator performance. This study performed RNA-seq testes Gushi roosters with high low identified differentially expressed RNAs involved motility. analysis showed that 73 67 mRNAs were up- downregulated, 47 56 long non-coding respectively. genes related to spermatogenesis included KIFC1, KCNK2, REC8. Functional enrichment revealed pathways oxidative...

10.1016/j.psj.2022.102183 article EN cc-by-nc-nd Poultry Science 2022-09-14

The development and egg-laying performance of hens are precisely regulated by hormones secreted the pituitary. In this study, we performed comprehensive transcriptome sequencing pituitary from Hy-Line Brown at 15, 20, 30 68 W age. Through association analysis, identified key genes ceRNA regulatory networks related to egg production. Based on data, 470 differentially expressed lncRNAs (DE-lncRNAs), 38 miRNAs (DE-miRNAs), 2,449 mRNAs (DE-mRNAs). Time-series analysis pinpointed signaling...

10.1186/s12864-024-11035-1 article EN cc-by-nc-nd BMC Genomics 2024-11-18

Undoped ZnO and doped films were deposited on the MgO(111) substrates using oxygen plasma-assisted molecular beam expitaxy. The orientations of grown thin film investigated by in situ reflection high-energy electron diffraction ex x-ray (XRD). roughness was measured atomic force microscopy, which correlated with grain sizes determined XRD. Synchrotron-based absorption spectroscopy performed to study doping effect electronic properties films, compared density functional theory calculations....

10.1088/1674-1056/25/7/076105 article EN Chinese Physics B 2016-07-01

To study the effect of Lichong Decoction (Lichong for strengthening anti-pathogenic Qi and eliminating blood stasis) on expression insulin-like growth factor-l (IGF-I) proliferating cell nuclear antigen (PCNA) mRNA in a rat model uterine leiomyoma. Fifty female Wistar rats were randomized into normal control group, Guizhifuling Capsule (Capsule containing Cassia Twig Poria) Mifepristone group. The leiomyoma was established by peritoneal injections exogenous estrogen progesterone hormone....

10.1016/s0254-6272(13)60084-9 article EN cc-by-nc-nd Deleted Journal 2012-12-01

The study attempted to elucidate whether lipid genes are closely associated with metabolic abnormalities during the lithogenic time and how Yinchenhao Decoction (YCHD) works on transcriptions of against cholesterol gallstone model. C57BL/6J mice fed diet (LD) were used for model establishment randomized into 5 groups. All groups received LD different weeks isometrically intragastric administration YCHD or NS. Biochemical tests measured liver tissues harvested histological genetic detection....

10.1155/2018/8134918 article EN cc-by Evidence-based Complementary and Alternative Medicine 2018-01-01

Abstract Carboxyl ester lipase (CEL) encodes a cholesterol hydrolase that is secreted into the duodenum as component of pancreatic juice. The objective this study was to characterize CEL gene, investigate association between promoter variants and chicken phenotypic traits, explore gene regulatory mechanism. An insertion/deletion (indel) caused by 99-bp insertion fragment shown for first time in promoter, large differences allelic frequency were found among commercial breeds, indigenous feral...

10.1038/s41598-020-60168-2 article EN cc-by Scientific Reports 2020-02-21

Astragaloside IV (AS-IV) is a chemical found in traditional Chinese medicine called Astragalus membranaceus (Fisch.) Bunge that has antitumor properties. However, the roles and mechanisms of AS-IV uterine leiomyomas (ULMs) are unclear. The immunosuppressive enzyme indoleamine-2,3-dioxygenase-1 (IDO1) involved tumor formation. IDO1 new reliable prognostic indicator for several cancers. In this work, was applied to ULM cells various concentrations. CCK-8, immunofluorescence, flow cytometry...

10.3390/cancers14184424 article EN Cancers 2022-09-12
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