Xiaofeng Liang

ORCID: 0000-0001-6918-7932
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About
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Research Areas
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Hepatitis Viruses Studies and Epidemiology
  • Vaccine Coverage and Hesitancy
  • Liver Disease Diagnosis and Treatment
  • Viral Infections and Vectors
  • Bacterial Infections and Vaccines
  • Systemic Lupus Erythematosus Research
  • Viral Infections and Outbreaks Research
  • Mosquito-borne diseases and control
  • Atherosclerosis and Cardiovascular Diseases
  • Dermatological diseases and infestations
  • Respiratory viral infections research
  • interferon and immune responses
  • Higher Education and Teaching Methods
  • Pneumonia and Respiratory Infections
  • Cancer-related molecular mechanisms research
  • Parkinson's Disease Mechanisms and Treatments
  • Influenza Virus Research Studies
  • HIV, Drug Use, Sexual Risk
  • IL-33, ST2, and ILC Pathways
  • Substance Abuse Treatment and Outcomes
  • Immune responses and vaccinations
  • Diphtheria, Corynebacterium, and Tetanus
  • Hydrogels: synthesis, properties, applications

Southern Medical University
2016-2025

Jinan University
2022-2025

Chinese Preventive Medicine Association
2021-2024

First Affiliated Hospital of Guangdong Pharmaceutical University
2024

Guangdong Pharmaceutical University
2024

Zhujiang Hospital
2022-2023

Prevention Institute
2023

Jiujiang Maternal and Child Care Centres
2022

Shanxi Medical University
2021

Zhejiang Runtu (China)
2017

Pneumococcal disease (PD) has a serious effect on older people aged 60 years and above. However, pneumococcal vaccination rates for in China remain low. This study aimed to explore adult children's perspectives the of their parents examine determinants vaccine hesitancy. In October 2022, cross-sectional survey was conducted Guangzhou, China. The questionnaire assesses data sociodemographic characteristics children parents, health beliefs about vaccination, variables measuring child–parent...

10.1080/21645515.2024.2440959 article EN cc-by-nc Human Vaccines & Immunotherapeutics 2025-01-05

Abstract The inefficient clearance of deep tumors and metastatic lesions greatly hinders the clinical applications photodynamic therapy (PDT). Inducing robust immunogenic cell death (ICD) is crucial for improving PDT outcomes, as ICD‐mediated T‐cell adaptive immune responses suppress tumor recurrence metastasis. Sustained endoplasmic reticulum (ER) stress essential activating ICD, however, inadequate photosensitizer enrichment in ER cell‐protective mechanisms, such unfolded protein response...

10.1002/adfm.202424108 article EN Advanced Functional Materials 2025-03-16

During September 2006-December 2009, we conducted active population and sentinel laboratory-based surveillance for bacterial meningitis pathogens, including Streptococcus pneumoniae, Neisseria meningitidis, Haemophilus influenzae type b, in 4 China prefectures. We identified 7,876 acute encephalitis syndrome cases, 6,388 among prefecture residents. A total of 833 resident cases from hospitals met the World Health Organization case definition probable meningitis; 339 these were children <5...

10.3201/eid2001.120375 article EN cc-by Emerging infectious diseases 2013-11-26

We conducted a follow-up survey for 55 Japanese encephalitis (JE) cases 1–2 years after hospital discharge in Gansu province, China. Community-, education-, and gender-matched healthy individuals without history of neurologic disease were selected as the comparison group. All subjects received neurological examination, intelligence quotient (IQ) measurement, adaptive behavior Wechsler memory scale (WMS) assessment. found 43.6% JE had at least one nervous system sequelae compared with 3.6%...

10.4269/ajtmh.14-0148 article EN American Journal of Tropical Medicine and Hygiene 2015-04-28

Abstract Background The HIV and other sexually transmitted infections (STI) excluding among the elderly population urgently require more attention in-depth study. We aimed to present predict worldwide of its burden from 1990 2030 using data Global Burden Disease (GBD) Methods Leveraging 2019 GBD study, we investigated average annual percentage change (AAPC) STI in incidence, prevalence, disability-adjusted life years (DALYs), mortality rates for individuals aged 50–69 across different age...

10.7189/jogh.14.04105 article EN cc-by Journal of Global Health 2024-07-19

It has been reported that hsa_circRNA_100833 (identified as circFADS2) and miR-133a play opposite roles in LPS-induced cell apoptosis, which contributes to the development of sepsis. This study was carried out explore interaction between circFADS2 sepsis.Expression plasma from both sepsis patients (n=62) healthy controls studied by RT-qPCR. Pearson's correlation coefficient analysis utilized analyze levels across samples patients. Cell viability proteins associated with apoptosis (cleaved...

10.1186/s12950-022-00300-3 article EN cc-by Journal of Inflammation 2022-03-12

The twin aims of this study were to investigate the changes in anti-HBs IgG levels after booster vaccinations and compare effects different vaccine doses children aged 11-15 years who both negative for HBsAg had an Anti-HBs

10.4161/hv.7.10.15990 article EN Human Vaccines 2011-10-01

Hepatitis B vaccine (HepB) has been routinely recommended as part of the immunization program in China and had a satisfactory safety effectiveness profile protecting infants from hepatitis virus infection. We evaluated surveillance sensitivity changes over time AEFI reports related to HepB among based on consistent national data before after introduction administration law (LAW) 2013 2020 China.

10.3389/fimmu.2022.956473 article EN cc-by Frontiers in Immunology 2022-09-30

Systemic lupus erythematosus (SLE) is a complex heterogeneous systemic autoimmune disease. Previous studies have shown that SLE may be related to diffuse large B cell lymphoma (DLBCL), but the mechanism of their relationship still unclear. The present study aimed explore common genetic molecular mechanisms, core shared genes, and miRNAs between DLBCL as well investigate diagnostic markers DLBCL.The microarray data were downloaded from comprehensive Gene Expression Omnibus (GEO) database....

10.1177/09612033221114578 article EN Lupus 2022-07-11

Hemodialysis (HD) patients represent a high-risk group for hepatitis B infection. It is crucial to administer vaccination and stimulate higher more sustained levels of anti-HBs. Our aim enhance the immunogenicity persistence by implementing high-dose prolonged vaccine schedule regimen in HD patients.

10.1093/infdis/jiae494 article EN The Journal of Infectious Diseases 2024-10-08

The non/hypo-response rate of the hepatitis B vaccine among hemodialysis (HD) patients is still high, it great significance to explore influencing factors and their relationships. To study related relationships using logistic regression model Chi-squared Automatic Interaction Detection (CHAID) decision tree model. A randomized controlled trial was conducted between February 2014 May 2015 in China. HD being serologically negative for HBsAg anti-HBs were randomly assigned receive three...

10.1080/21645515.2021.1895603 article EN Human Vaccines & Immunotherapeutics 2021-05-14

<title>Abstract</title> <bold>Background</bold> Colorectal cancers (CRC) have been suggested to be involved with coliform bacteria, while the association small intestinal bacteria is not clear. The study objective was investigate relationship between patients CRC and gas production characteristics of using lactulose breath test (LBT).<bold>Methods</bold> Data on age, gender, body mass index (BMI), hydrogen methane concentrations at various time points, colonoscopy results bowel diseases were...

10.21203/rs.3.rs-4791552/v1 preprint EN cc-by Research Square (Research Square) 2024-09-02

<title>Abstract</title> Background The skin serves as a crucial barrier against microbial invasion, but breaches in this can lead to infectious diseases (ISD). ISD, including bacterial (BSD), fungal (FSD) and viral Skin Disease (VSD), pose significant global health challenges. Methods Age-standardized age specific incidence, prevalence, lived with disability (YLDs) data for ISD were sourced from the Global Burden of Study 2021 (GBD 2021) demographic United Nations. We utilized linear...

10.21203/rs.3.rs-5286808/v1 preprint EN cc-by Research Square (Research Square) 2024-10-23
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