- Microbial Community Ecology and Physiology
- Microbial bioremediation and biosurfactants
- Chromium effects and bioremediation
- Veterinary Oncology Research
- Virus-based gene therapy research
- Extracellular vesicles in disease
- Immune cells in cancer
- Immune Cell Function and Interaction
- Microbial Fuel Cells and Bioremediation
- Hemoglobin structure and function
- Cervical Cancer and HPV Research
- Neonatal Health and Biochemistry
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
- Toxic Organic Pollutants Impact
- Mass Spectrometry Techniques and Applications
- Environmental Toxicology and Ecotoxicology
- Pesticide and Herbicide Environmental Studies
- Gut microbiota and health
- Mercury impact and mitigation studies
- Electron Spin Resonance Studies
- Metal Extraction and Bioleaching
- Genital Health and Disease
- Veterinary Medicine and Surgery
- Trace Elements in Health
Istituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta
2023-2025
University of Pavia
2024
Stazione Zoologica Anton Dohrn
2018-2022
Marche Polytechnic University
2018
University of Genoa
2015-2016
Coastal areas impacted by high anthropogenic pressures typically display sediment contamination polycyclic aromatic hydrocarbons (PAHs) and heavy metals (HMs). Microbial-based bioremediation represents a promising strategy for reclamation, yet it frequently fails due to poor knowledge of the diversity dynamics autochthonous microbial assemblages inhibition target microbes in contaminated matrix. In present study, we used an integrated approach including detailed environmental...
Investigations on the ability of bacteria to enhance removal hydrocarbons and reduce heavy metal toxicity in sediments are necessary design more effective bioremediation strategies. In this study, five bacterial strains, Halomonas sp. SZN1, Alcanivorax SZN2, Pseudoalteromonas SZN3, Epibacterium SZN4, Virgibacillus SZN7, were isolated from polluted an abandoned industrial site Gulf Naples, Mediterranean Sea, tested for their efficiency sediment samples collected same site. These added as...
The contamination of coastal marine sediments with heavy metals (HMs) is a widespread phenomenon that requires effective remediation actions. Bioremediation based on the use bacteria an economically and environmentally sustainable strategy for reducing HM and/or toxicity in sediments. However, information efficiency marine-derived fungi decontamination still largely lacking, despite evidence performance terrestrial fungal strains other contaminated matrixes (e.g., soils, freshwater...
Extracellular vesicles (EVs) are nanometric-membrane-bound sub-cellular structures, which can be recovered from milk. Milk EVs have drawn increasing interest due to their potential biomedical applications, therefore it is important investigate impact on key immune cells, such as macrophages.In this work, the immunomodulatory effects of goat milk untreated (moMФ) and classically activated (moM1) porcine monocyte-derived macrophages were investigated using flow cytometry, ELISA, gene...
Swine are attracting increasing attention as a biomedical model, due to many immunological similarities with humans. However, porcine macrophage polarization has not been extensively analyzed. Therefore, we investigated monocyte-derived macrophages (moMΦ) triggered by either IFN-γ + LPS (classical activation) or diverse "M2-related" polarizing factors: IL-4, IL-10, TGF-β, and dexamethasone. polarized moMΦ toward proinflammatory phenotype, although significant IL-1Ra response was observed....
Papillomaviruses (PVs) are small, non-enveloped viruses, ubiquitous across the animal kingdom. PVs induce diverse forms of infection, such as cutaneous papillomas, genital papillomatosis, and carcinomas. During a survey on fertility status mare, novel Equus caballus PV (EcPV) has been identified using Next Generation Sequencing, it was further confirmed with genome-walking PCR Sanger sequencing. The complete circular genome 7607 bp long shares 67% average percentage identity EcPV9, EcPV2,...
Extreme environments host numerous microorganisms perfectly adapted to survive in such harsh conditions. In recent years, many bacteria isolated from these inhospitable have shown interesting biotechnological applications, including the bioremediation of polluted sites by hydrocarbons and heavy metals. this work, we present Dietzia psychralcaliphila JI1D, a psychrophilic bacterium, Deception Island, Antarctica, which is able resist high concentrations (up 1000 ppm) metals favor their removal...
Cancer is a leading cause of death in cats, and the rate such disease has been increasing recently. Nonetheless, feline oncology represents an important area study not only for health wellbeing cats but also human since various types cancer share similarities to those found humans. Therefore, epidemiological studies on may suggest environmental genetic factors contributing which can eventually be translated improve care.
Abstract Oceanicaulis alexandrii strain NP7 is a marine bacterium which belongs to the Hyphomonadaceae family and was isolated from sediments highly contaminated with metals polycyclic aromatic hydrocarbons released for decades by industrial activities in Gulf of Naples (Mediterranean Sea). Here, we report partial genome sequence annotation O. that contains chromosome 2,954,327 bp encodes 2914 predicted coding sequences (CDSs) 44 RNA-encoding genes. Although presence some CDSs genes involved...
Swine are considered one of the most relevant large animal biomedical models since they share many immunological similarities with humans. Despite that, macrophage polarization has not comprehensively investigated in pigs. In this study, porcine monocyte-derived macrophages (moMΦ) were untreated or stimulated IFN-γ + LPS (classical activation), by different M2 polarizing stimuli: IL-4, IL-10, TGF-β, dexamethasone. Expression key cytokine genes (IL1B2, IL33, IL19, IL22, IL26, CCL17, CCL24,...
Here, we report the draft genome sequence of a metagenome-assembled (MAG) new Alkaliphilus bacterium, NP8, Clostridiaceae family. This bacterium was isolated from polluted sediment collected an abandoned industrial site located in Gulf Naples (Mediterranean Sea) as part microbial consortium.