Farhan Anwar Khan

ORCID: 0000-0001-6024-1269
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About
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Research Areas
  • Microbial infections and disease research
  • Aquaculture disease management and microbiota
  • Bacteriophages and microbial interactions
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Genetic and phenotypic traits in livestock
  • Animal Virus Infections Studies
  • Animal Diversity and Health Studies
  • Toxoplasma gondii Research Studies
  • Animal Disease Management and Epidemiology
  • Mycotoxins in Agriculture and Food
  • Plant Pathogenic Bacteria Studies
  • Reproductive Biology and Fertility
  • Viral Infections and Vectors
  • Plant Virus Research Studies
  • Analytical Chemistry and Sensors
  • Herpesvirus Infections and Treatments
  • Acupuncture Treatment Research Studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Selenium in Biological Systems
  • Brucella: diagnosis, epidemiology, treatment
  • Vector-borne infectious diseases
  • Milk Quality and Mastitis in Dairy Cows
  • Animal Nutrition and Physiology
  • Streptococcal Infections and Treatments

The University of Agriculture, Peshawar
2016-2025

Animal Husbandry & Veterinary
2018-2024

Sindh Agriculture University
2024

Civil Hospital Karachi
2023

University Research Co (United States)
2022

Huazhong Agricultural University
2014-2022

Lasbela University of Agriculture Water and Marine Science
2022

University of Karachi
2022

COMSATS University Islamabad
2013-2021

Orlando Health
2014

Aflatoxicosis is a grave threat to the poultry industry. Dietary supplementation with antioxidants showed great potential in enhancing immune system; hence, protecting animals against aflatoxin B1-induced toxicity. Grape seed proanthocyanidin extract (GSPE) one of most well-known and powerful antioxidants. Therefore, purpose this research was investigate effectiveness GSPE detoxification AFB1 broilers. A total 300 one-day-old Cobb chicks were randomly allocated into five treatments six...

10.3390/toxins9110371 article EN cc-by Toxins 2017-11-15

Aflatoxin B₁ (AFB₁) is a widely spread mycotoxin contaminates food and feed, causing severe oxidative stress damages immunotoxicity. Grape seed proanthocyanidin (GSPE), natural antioxidant with wide range of pharmacological medicinal properties. The goal the present study was to investigate protective effects GSPE against AFB₁-induced immunotoxicity via NF-κB Nrf2 signaling pathways in broiler chickens. For experiment, 240 one-day old Cobb chicks were allocated into four dietary treatment...

10.3390/toxins11010023 article EN cc-by Toxins 2019-01-07

Abstract Mycoplasma bovis causes considerable economic losses in the cattle industry worldwide. In mycoplasmal infections, adhesion to host cell is of utmost importance. this study, amino acid sequence NOX was predicted have enzymatic domains. The nox gene then cloned and expressed Escherichia coli . activity recombinant (rNOX) confirmed based on its capacity oxidize NADH NAD + reduce O 2 H adherence rNOX embryonic bovine lung (EBL) cells with confocal laser scanning microscopy,...

10.1038/s41598-017-00121-y article EN cc-by Scientific Reports 2017-02-27

Globally, ruminants contribute largely to the livelihood and supply of quality food for human consumption. However, small face numerous problems, including infectious diseases, in lower- middle-income countries (LMIC). Brucellosis is one important zoonotic diseases affecting range animals caused by Brucella species, abortus mellitensis. Although brucellosis B. mellitensis has never been reported study areas, its importance can be underestimated. Therefore, this was designed investigate...

10.1371/journal.pone.0315206 article EN cc-by PLoS ONE 2025-02-07

This study identified urinary biomarkers for tuberculosis (TB) diagnosis. The urine proteomic profiles of 45 pulmonary patients prior to anti-TB treatment and healthy controls were analyzed compared using two-dimensional electrophoresis with matrix-assisted laser desorption/ionization time flight mass spectrometry. Nineteen differentially expressed proteins preliminarily, western blotting qRT-PCR performed confirm these changes at the translational transcriptional levels, respectively,...

10.1038/s41426-018-0066-5 article EN cc-by Emerging Microbes & Infections 2018-04-11

Mycoplasma bovis is an important cause of bovine respiratory disease worldwide. To understand its virulence mechanisms, we sequenced three attenuated M. strains, P115, P150, and P180, which were passaged in vitro 115, 150, 180 times, respectively, exhibited progressively decreasing virulence. Comparative genomics was performed among the wild-type HB0801 (P1) strain P180 one 14.2-kb deleted region covering 14 genes detected strains. Additionally, 46 non-sense single-nucleotide polymorphisms...

10.3389/fcimb.2017.00177 article EN cc-by Frontiers in Cellular and Infection Microbiology 2017-05-11

Mycoplasma bovis is an important pathogenic mycoplasma, causing the cattle industry serious economic losses. Adhesion a crucial step in mycoplasmas' infection and colonization process; fibronectin (Fn), extracellular matrix glycoprotein, molecular bridge between bacterial adhesins host cell receptors. The present study was designed to characterize Fn-binding ability of methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (TrmFO) its role M. cytoadherence. trmFO (MBOV_RS00785) gene...

10.3390/ijms18081732 article EN cc-by International Journal of Molecular Sciences 2017-08-09

// Farhan Anwar Khan 1,2,3,* , Muhammad Faisal 1,2,* Jin Chao 1,2 Kai Liu Xi Chen 2 Gang Zhao Harish Menghwar Hui Zhang Xifang Zhu Asif Rasheed Chenfei He Changmin Hu Yingyu 1,4 Eric Baranowski 6,7 Huanchun 1,2,4 and Aizhen Guo 1,2,4,5 1 The State Key Laboratory of Agricultural Microbiology, Huazhong University, Wuhan, China College Veterinary Medicine, 3 Department Animal Health, University Agriculture, Peshawar, Pakistan 4 Development Diagnostic Products, Ministry International Joint...

10.18632/oncotarget.9799 article EN Oncotarget 2016-06-02

Limited data suggest that tigecycline may be of value in the treatment Clostridiumdifficile infection. We reviewed our experience using to treat severe c. difficile and compared outcomes similarly ill patients who did not receive tigecycline. found no difference between groups. Further study is needed before can recommended for use C.

10.1016/j.ijid.2014.04.025 article EN cc-by-nc-nd International Journal of Infectious Diseases 2014-07-23

Summary Mycobacterium tuberculosis ( M. ) regions of difference RD encode proteins which are potentially useful as diagnostic reagents for TB ). In this study, 75 genes from 1‐ 16 were successfully cloned 68 expressed and purified. Three serum pools patients with pulmonary PTB ), extra‐pulmonary EPTB healthy controls HC used to preliminarily screen individual proteins. The OD 630 ratio the or group ≥ 2‐fold was positive. As a result, 29 obtained. serological response identified antigens...

10.1111/1751-7915.13291 article EN cc-by Microbial Biotechnology 2018-06-27

Mycoplasma capricolum subsp. capripneumoniae (Mccp) causes a severe, usually fatal disease in goats known as Contagious Caprine Pleuropneumonia (CCPP). CCPP is listed by OIE notifiable animal diseases, causing economic losses terms of high morbidity and mortality. Thus far, very limited information available on the molecular characterization unique Mccp strains prevalent Pakistan. The study was aimed to isolate local strain for development diagnostics vaccines. Samples were collected during...

10.1016/j.jmii.2020.06.002 article EN cc-by-nc-nd Journal of Microbiology Immunology and Infection 2020-06-10

Achai is a small size cattle breed, resilient to harsh and cold environment. Cryopreservation of bull semen may help improve its genetics preserve the germplasm. Reactive oxygen species (ROS) affects structural functional integrity spermatozoa. During freezing thawing processes, ROS make changes in spermatozoa quality parameters reduce total antioxidant capacity (T-AOC) that considered as marker oxidative stress. This study was designed determine effect glycine along with vitamin E on...

10.1155/2022/8282387 article EN cc-by BioMed Research International 2022-08-04

Mycoplasma bovis is a critical bovine pathogen, but its pathogenesis remains poorly understood. Here, the virulent HB0801 (P1) and attenuated HB0801-P150 (P150) strains of M. were used to explore potential effect induced immunity from calves’ differential transcriptomes post infection. Nine one-month-old male calves infected with P1, P150, or mock-infected medium euthanized at 60 days post-infection. Calves in P1 group exhibited other clinical signs pathological changes compared two groups....

10.3390/genes10090656 article EN Genes 2019-08-28
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