A5100399911- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Marine animal studies overview
- Immune Cell Function and Interaction
- Insect-Plant Interactions and Control
- Marine and fisheries research
- T-cell and B-cell Immunology
- Genomics and Phylogenetic Studies
- Cephalopods and Marine Biology
- Reproductive biology and impacts on aquatic species
- Marine Bivalve and Aquaculture Studies
- GABA and Rice Research
- Plant Virus Research Studies
- Immunotherapy and Immune Responses
- Fish Ecology and Management Studies
- Rice Cultivation and Yield Improvement
- Microbial infections and disease research
- Insect and Pesticide Research
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Fish Biology and Ecology Studies
- Immune Response and Inflammation
- Neurobiology and Insect Physiology Research
- Gut microbiota and health
- Reproductive System and Pregnancy
Kunming Children's Hospital
2025
Shanghai Ocean University
2016-2024
Hubei Academy of Agricultural Sciences
2023-2024
Ministry of Agriculture and Rural Affairs
2019-2024
Hong Kong University of Science and Technology
2024
University of Hong Kong
2024
Chinese Academy of Fishery Sciences
2016-2024
Nanjing Agricultural University
2022-2024
Shanghai Zhangjiang Laboratory
2023-2024
Second Affiliated Hospital of Nanjing Medical University
2024
This study aimed to evaluate whether galectin-3 (Gal-3) contributes actively atrial fibrosis both in patients and experimental fibrillation (AF) models.Mouse HL-1 cardiomyocytes were subjected rapid electrical stimulation (RES) explore Gal-3 expression secretion levels by western blotting (WB) enzyme linked immunosorbent assay (ELISA). Neonatal rat cardiac fibroblasts treated with conditioned culture medium recombinant human the activation of transforming growth factor (TGF)-β1/α-smooth...
Allergic asthma is an inflammatory disorder of the airway without satisfactory traditional therapies capable controlling underlying pathology. New approaches that can overcome detrimental effects immune dysregulation are thus desirable. Here we adoptively transfer ovalbumin (OVA) peptide-primed CD4-CD8- double negative T (DNT) cells intravenously into a mouse model OVA-induced allergic to find hyperresponsiveness, lung inflammation, mucus production and OVA-specific IgG/IgE significantly...
Abstract Obesity is a prevalent health issue among adolescents, characterized by chronic low-grade inflammation, which increases the risk of developing various diseases in future. The systemic immune-inflammation index (SII) serves as an indicator inflammation and immune response. This study conducted cross-sectional analysis using data from National Health Nutrition Examination Survey (NHANES) 2007 to 2016, including 5,676 participants. A multivariate logistic regression model, Generalized...
Abstract Hepatic inflammation is the driving force for development and progression of NASH. Treatment targeting believed to be beneficial. In this study, adoptive transfer CD4 + T cells converted double negative (cDNT) protects mice from diet-induced liver fat accumulation, lobular focal necrosis. cDNT selectively suppress liver-infiltrating Th17 proinflammatory M1 macrophages. IL-10 secreted by M2 macrophages decreases survival function protect cDNT-mediated lysis. NKG2A, a cell inhibitory...
The γδ T cell is a promising candidate in tumor immunotherapy. However, cells polarize to CD39+γδ Tregs upon colorectal cancer (CRC) induction, and the underlying mechanism remains unclear. Here, we show that frequency of Tregs, which positively correlated with poor prognosis, was significantly higher right-sided CRC (RSCRC) than left-sided (LSCRC). Interestingly, from RSCRC showed stronger immunosuppressive phenotype function LSCRC. Furthermore, quantitative mass spectrometry data Treg...
// Farhan Anwar Khan 1,2,3,* , Muhammad Faisal 1,2,* Jin Chao 1,2 Kai Liu Xi Chen 2 Gang Zhao Harish Menghwar Hui Zhang Xifang Zhu Asif Rasheed Chenfei He Changmin Hu Yingyu 1,4 Eric Baranowski 6,7 Huanchun 1,2,4 and Aizhen Guo 1,2,4,5 1 The State Key Laboratory of Agricultural Microbiology, Huazhong University, Wuhan, China College Veterinary Medicine, 3 Department Animal Health, University Agriculture, Peshawar, Pakistan 4 Development Diagnostic Products, Ministry International Joint...
Cold damage is one of the most important environmental factors influencing crop growth, development, and production. In this study, we generated a pair near-isogenic lines (NILs), Towada ZL31, showed more cold sensitivity than ZL31 in rice seedling stage. To explore transcriptional regulation mechanism reason for phenotypic divergence two response to stress, an in-depth comparative transcriptome study under stress was carried out. Our analysis uncovered that rapid high-amplitude...
Abstract Background The Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis, YFP) and the East Asian sunameri, EFP) are 2 subspecies of narrow-ridged that live in freshwater saltwater, respectively. main objective this study was to provide contiguous chromosome-level genome assemblies for YFP EFP. Results Here, we generated upgraded genomes EFP at telomere-to-telomere level through integration PacBio HiFi long reads, ultra-long ONT Hi-C sequencing data with a total size...
Abstract The Chinese tapertail anchovy, Coilia nasus , is a socioeconomically important anadromous fish that migrates from near ocean waters to freshwater spawn every spring. analysis of genomic architecture and information C. were hindered by the previously released versions reference genomes with gaps. Here, we report assembly chromosome-level gap-free genome incorporating high-coverage accurate long-read sequence data multiple strategies. All 24 chromosomes assembled without gaps,...
Neutrophils are characterized by their heterogeneity. They fight against pathogens and involved in tissue injury repair immune system regulation. have an extremely short life span the peripheral blood undergo aging after being released from bone marrow. The over-aggregation of aged neutrophils is associated with phenotypical functional changes. Here, we aimed to investigate dynamics neutrophil its relationship T cell exhaustion HIV-1 infection, as they not well understood. In this study,...
Apple leaf spot, caused by the Alternaria alternata apple pathotype (AAAP), is an important fungal disease of apple. To understand molecular basis resistance and pathogenesis in transcriptomes two cultivars 'Hanfu' (HF) (resistant) 'Golden Delicious'(GD) (susceptible) were analyzed at 0, 6, 18, 24 48 hours after AAAP inoculation RNA-seq. At each time point, a large number significantly differentially expressed genes (DEGs) screened between AAAP-inoculated uninoculated leaves. Analysis common...
Mycoplasma bovis is a critical bovine pathogen, but its pathogenesis remains poorly understood. Here, the virulent HB0801 (P1) and attenuated HB0801-P150 (P150) strains of M. were used to explore potential effect induced immunity from calves’ differential transcriptomes post infection. Nine one-month-old male calves infected with P1, P150, or mock-infected medium euthanized at 60 days post-infection. Calves in P1 group exhibited other clinical signs pathological changes compared two groups....
An increase in the activity of pituitary-gonad axis (PG-axis) and gonad development are essential for onset spawning migration teleosts. In fish Coilia nasus, up Yangtze River occurs by end each summer. We hypothesized that gonadotropin releasing hormones receptor 2 (GnRH-R2), which together produce a signal interacts with PG-axis, may help to regulate processes.In this regard, we (1) characterized gonadosomatic index (GSI) anadromous C. nasus; (2) analyzed GnRH-R2 mRNA expression levels...
This study aimed to explore the feasibility of using an upper beak microstructure estimate age purpleback flying squid (Sthenoteuthis oualaniensis). From these microstructures, and growth caught from January March May August in 2018, 2019, 2020 waters surrounding Xisha Islands South China Sea were determined. We found three typical zones (the hood region, crest axis), abnormal increments (checks), erosion examination. The average dorsal mantle length (ML) males females was 112.13 (±15.23 mm)...
The Yangtze finless porpoises (
Cold stress has a significantly negative effect on the growth, development, and yield of rice. However, genetic basis for differences in cold tolerance Xian/indica Geng/japonica rice seedlings is still largely unknown. In this study, an RIL population was generated by crossing cold-tolerant japonica variety Nipponbare cold-sensitive indica WD16343 BSA-seq analysis, major QTL qCTS11 identified chromosome 11. This locus narrowed to 584 kb region through fine mapping. Sequence alignment...
In this study, we investigated the activity levels of two major digestive enzymes (pepsin and lipase) in commercially important Japanese grenadier anchovy Coilia nasus during its upstream migration to analyse physiological responses starvation influence water temperature on enzyme activity. Water had a significant effect pepsin activity, while long-term resulted decrease As continued, however, slight increase between Wuhu (440 river km) Anqing (620 regions may indicate that C. refeeding...
The potential role of peroxisome proliferator-activated receptor (PPAR) in regulating the biosynthesis long-chain polyunsaturated fatty acids (LCPUFA) has not been explored marine gastropod. In this study, we identified and characterized a PPAR gene from abalone species Haliotis discus hannai Ino. This encodes peptide consisting 469 amino comprises typical four domains: A/B domain, DNA-binding D ligand-binding domain. Highest homology with that Patella depressa (51.08 %) multiple alignments...