Timothy Thiruchelvam

ORCID: 0000-0001-6074-5280
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About
Contact & Profiles
Research Areas
  • Mechanical Circulatory Support Devices
  • Cardiac Structural Anomalies and Repair
  • Cardiac Arrest and Resuscitation
  • Congenital Heart Disease Studies
  • Neonatal Respiratory Health Research
  • Transplantation: Methods and Outcomes
  • Kawasaki Disease and Coronary Complications
  • Congenital Diaphragmatic Hernia Studies
  • Cardiac pacing and defibrillation studies
  • Tracheal and airway disorders
  • Heart Failure Treatment and Management
  • Intensive Care Unit Cognitive Disorders
  • Viral Infections and Immunology Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Voice and Speech Disorders
  • Healthcare Decision-Making and Restraints
  • RNA modifications and cancer
  • Cardiac electrophysiology and arrhythmias
  • Bacterial Infections and Vaccines
  • Family and Patient Care in Intensive Care Units
  • Emergency and Acute Care Studies
  • Pulmonary Hypertension Research and Treatments
  • COVID-19 Impact on Reproduction
  • Cardiovascular and Diving-Related Complications
  • Trauma Management and Diagnosis

Great Ormond Street Hospital
2014-2024

University College London
2014-2024

Great Ormond Street Hospital for Children NHS Foundation Trust
2015-2024

Royal Brompton Hospital
2022

National Health Service
2020

Children's Hospital of Philadelphia
2018

University of Pennsylvania
2018

University of Utah
2018

Kennedy Krieger Institute
2018

Johns Hopkins University
2018

Przemysław Szafrański Tomasz Gambin Avinash V. Dharmadhikari Kadir C. Akdemir Shalini N. Jhangiani and 88 more Jennifer Schuette Nihal Godiwala Svetlana A. Yatsenko Jessica Sebastian Suneeta Madan‐Khetarpal Urvashi Surti Rosanna Abellar David Bateman Ashley Wilson Melinda H. Markham Jill Slamon Fernando Santos‐Simarro María Palomares‐Bralo Julián Nevado Pablo Lapunzina Brian Hon‐Yin Chung Wai-Lap Wong Yoyo Wing Yiu Chu Gary Tsz Kin Mok Eitan Kerem Joel Reiter Namasivayam Ambalavanan Scott Anderson David R. Kelly Joseph T.C. Shieh Taryn C. Rosenthal Kristin Scheible Laurie A. Steiner M. Anwar Iqbal Margaret L. McKinnon Sara Hamilton Kamilla Schlade‐Bartusiak D. W. English Glenda Hendson Elizabeth Roeder Thomas S. DeNapoli Rebecca O. Littlejohn Daynna J. Wolff Carol L. Wagner Alison Yeung David Francis Elizabeth K. Fiorino Morris Edelman Joyce E. Fox Denise A. Hayes Sandra Janssens Elfride De Baere Björn Menten Anne Loccufier Lieve Vanwalleghem Philippe Moerman Yves Sznajer Amy S. Lay Jennifer Kussmann Jasneek Chawla Diane Payton Gael E. Phillips Erwin Brosens Dick Tibboel Annelies de Klein Isabelle Maystadt Richard Fisher Neil J. Sebire Alison Male Maya Chopra Jason Pinner Girvan Malcolm Gregory B. Peters Susan Arbuckle Melissa Lees Zoe Mead Oliver Quarrell Richard Sayers Martina Owens Charles Shaw‐Smith Janet Lioy Eileen McKay Nicole de Leeuw Ilse Feenstra Liesbeth Spruijt Frances Elmslie Timothy Thiruchelvam Carlos A. Bacino Claire Langston James R. Lupski Partha Sen Edwina J. Popek Paweł Stankiewicz

10.1007/s00439-016-1655-9 article EN Human Genetics 2016-04-12

To establish the effectiveness of a "1-year extracorporeal membrane oxygenation follow-up clinic" and to characterize any neurodevelopmental concerns identified.Single-center retrospective cohort respiratory survivors over 10 years.Nationally commissioned center for neonatal pediatric (> 28 d life) oxygenation.Children attending clinic 1 year after receiving between 2003 2013.Standardized oxygenation.In years, 290 children received oxygenation, 194 (67%) survived; all were offered 1-year...

10.1097/pcc.0000000000001304 article EN Pediatric Critical Care Medicine 2017-09-15

A third paediatric report has been generated from the European Registry for Patients with Mechanical Circulatory Support (EUROMACS). The purpose of EUROMACS, which is operated by Association Cardio-Thoracic Surgery, to gather data related durable mechanical circulatory support scientific purposes and publish reports respect course therapy. Since first issued, efforts increase compliance participation have extended. Additionally, provided opportunity analyse patients younger age lower...

10.1093/ejcts/ezac355 article EN European Journal of Cardio-Thoracic Surgery 2022-06-27

The Berlin Heart EXCOR (BHE) offers circulatory support across all paediatric ages. Clinically, the necessary care and outcomes differ in various age groups. EUROMACS database was used to study age- size-related for this specific device.All patients <19 years of from supported with a BHE between 2000 November 2021 were included. Maximally selected rank statistics determine body surface area (BSA) cut-off values. Multivariable Cox proportional hazard regression using ridge penalization...

10.1093/ejcts/ezac516 article EN cc-by European Journal of Cardio-Thoracic Surgery 2022-11-07

The Royal Children's Hospital, Melbourne, Victoria, provides extracorporeal life support (ECLS) for infants and children from all around Australia. Since 2003, we have offered a mobile ECLS service to retrieve critically ill whose condition is too unstable conventional transport. retrieval team comprises paediatric intensive care unit specialist, an nurse perfusionist cardiac surgeon.Retrospective review of eight (aged between 1 day 8 years) who were transported on the at 2003 2007.Seven...

10.1016/s1441-2772(23)01071-2 article EN cc-by-nc-nd Critical Care and Resuscitation 2008-03-01

Objectives: To examine parental experiences of childhood extracorporeal membrane oxygenation survivors to understand: 1) the problems children faced and 2) support received following hospital discharge. Design: Single-center descriptive study. Setting: Nationally commissioned center for neonatal pediatric oxygenation. Patients: All traceable less than 18 years old who from January 1998 April 2013. Intervention: Anonymized postal questionnaire completed by parents survivors. Measurements Main...

10.1097/pcc.0000000000002253 article EN Pediatric Critical Care Medicine 2020-02-25

Critical paediatric COVID-19: varied presentations but good outcomes Parenchymal changes including acute on chronic 8 (36) *Pre-existing respiratory disorder included lung disease and non-cystic fibrosis bronchiectasis.†Two of the children presented had previously defined epilepsy.‡Equivocal growth Staphylococcus aureus Candida albicans.PICU, intensive care unit; PICU, PIM3, index mortality version 3; RSV, syncytial virus; RT-PCR, reverse transcription polymerase chain reaction; SARS-CoV-2,...

10.1136/archdischild-2020-319602 article EN other-oa Archives of Disease in Childhood 2020-06-29

Ventricular assist device support as a bridge to transplant or recovery is well-established therapy in children on the cardiac waiting list. The goal of this study was investigate incidence and associated factors for cerebrovascular accidents paediatric patients supported by Berlin Heart EXCOR.All <19 years age EXCOR between January 2011 2021 from European Registry Patients with Mechanical Circulatory Support were included.In total, 230 included. A total 140 (60.9%) had diagnosis dilated...

10.1093/ejcts/ezac381 article EN cc-by European Journal of Cardio-Thoracic Surgery 2022-07-18

The use of ventricular assist devices (VADs) in children is increasing. However, absolute numbers individual centres and countries remain small. Collaborative efforts such as the Paedi-European Registry for Patients with Mechanical Circulatory Support (EUROMACS) are therefore essential combining international experience paediatric VADs. Our goal was to present results from fourth Paedi-EUROMACS report.

10.1093/ejcts/ezae276 article EN European Journal of Cardio-Thoracic Surgery 2024-07-19

A 2-day-old term baby was referred to our hospital for an urgent cardiology assessment because of respiratory collapse and complete ‘white-out’ a large left lung with mediastinal shift the right ( Panel ). At time admission infant on high-frequency oscillatory ventilation, inhaled nitric oxide, high-dose inotropes, Prostin infusion. Subsequent echocardiographic examination revealed pulmonary atresia …

10.1093/ehjci/jev347 article EN European Heart Journal - Cardiovascular Imaging 2016-01-21

Background and aims: The pneumatic 10 25 ml Berlin Heart EXCOR Ventricular Assist Devices [VAD] have improved heart transplant [HT] outcomes in children under 10kg body weight, although the risk of mortality remains higher when compared to larger children. Aims: To describe use novel 15 volume VAD two with restrictive left ventricular physiology. Methods: Case report. Institutional review board waiver for consent. Results: Child A, non-compaction cardiomyopathy, was cannulated ECMO at 33...

10.1097/01.pcc.0000449295.05187.06 article EN Pediatric Critical Care Medicine 2014-05-01
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