A5057379216- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Ethnobotanical and Medicinal Plants Studies
- Natural Antidiabetic Agents Studies
- Botanical Research and Chemistry
- Natural Language Processing Techniques
- Plant tissue culture and regeneration
- Topic Modeling
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Studies
- Speech and dialogue systems
- Plant and animal studies
- Plant Diversity and Evolution
- Botany, Ecology, and Taxonomy Studies
- Fern and Epiphyte Biology
- Medicinal Plants and Neuroprotection
- Chemical synthesis and alkaloids
- Plant and Fungal Species Descriptions
- Plant Parasitism and Resistance
- Text Readability and Simplification
- Phytochemistry and biological activities of Ficus species
- Healthcare and Venom Research
- Phytochemical and Pharmacological Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Alkaloids: synthesis and pharmacology
Laboratoire Lorrain de Recherche en Informatique et ses Applications
2020-2024
Université de Lorraine
2022
Centre National de la Recherche Scientifique
2022
Salvia miltiorrhiza is an important medicinal plant with great economic and value. The complete chloroplast (cp) genome sequence of miltiorrhiza, the first sequenced member Lamiaceae family, reported here. 151,328 bp in length exhibits a typical quadripartite structure large (LSC, 82,695 bp) small (SSC, 17,555 single-copy regions, separated by pair inverted repeats (IRs, 25,539 bp). It contains 114 unique genes, including 80 protein-coding 30 tRNAs four rRNAs. structure, gene order, GC...
Abstract Background Panax notoginseng (Burk) F.H. Chen is important medicinal plant of the Araliacease family. Triterpene saponins are bioactive constituents in P. . However, available genomic information regarding this limited. Moreover, details triterpene saponin biosynthesis species largely unknown. Results Using 454 pyrosequencing technology, a one-quarter GS FLX titanium run resulted 188,185 reads with an average length 410 bases for root. These were processed and assembled by De Novo...
Salvia miltiorrhiza is a Chinese herb with significant pharmacologic effects because of the bioactive compounds tanshinones and phenolic acids. Methyl jasmonate ( MeJA ) has been used as an effective elicitor to enhance production these compounds. However, molecular mechanism ‐mediated tanshinone salvianolic acid biosynthesis remains unclear. The transcriptional profiles S. leaves at 12 h T12 after elicitation mock‐treated T0 were generated using Illumina deep RNA sequencing ‐seq) strategy...
Rabdosia serra (R. serra), an important component of Chinese herbal tea, has traditionally been used to treat hepatitis, jaundice, cholecystitis, and colitis. However, the chemical composition R. its effect against colitis remain unclear. In this study, water extract was analyzed using ultra performance liquid chromatography coupled with a hybrid linear ion trap quadrupole-orbitrap mass spectrometer (UPLC-LTQ-Orbitrap-MS). A total 46 compounds, comprising ent-kaurane diterpenoids,...
Clemastanin B, 7S,8R,8'R-(-)-lariciresinol-4,4'-bis-O-β-D-glucopyranoside, is one of the major lignans extracted from Isatis indigotica root (IIR). In this study, anti-influenza activities clemastanin B were evaluated in vitro. was found to inhibit different subtypes human (H1N1, including swine-origin H1N1; H3N2 and influenza B) avian viruses (H6N2, H7N3, H9N2) at magnitudes activity (IC50 0.087-0.72 mg/ml) while compound inactive against respiratory syncytial virus (RSV), adenovirus 3...
Kouyanqing Granule (KYQG) is a traditional Chinese herbal formula composed of Flos lonicerae (FL), Radix scrophulariae (RS), ophiopogonis (RO), asparagi (RA), and et rhizoma glycyrrhizae (RG). In contrast with the typical method separating then biologicalily testing components individually, this study was designed to establish an approach in order define core bioactive ingredients anti-inflammatory effects KYQG based on relevance analysis between chemical characters biological effects....
This study aimed to investigate the effects of dietary isatidis root polysaccharide (IRP) on diarrhea, immunity, and intestinal health in weanling piglets. Forty healthy piglets were randomly assigned five groups receiving varying dosages IRP. The findings indicated that different concentrations IRP significantly reduced diarrhea scores (p < 0.01). Notably, serum levels immunoglobulin A G increased linearly quadratically 0.01), while M also showed a linear increase 0.05) IRP-fed secretory...
Naoxinqing (NXQ) tablets are derived from persimmon leaves and widely used in China for promoting blood circulation removing stasis China. We aimed to explore whether NXQ has the therapeutic effect on ischemic stroke explored its possible mechanism.
Depression is a serious mental illness that impacts the way people communicate, especially through their emotions, and, allegedly, they interact with others. This work examines depression signals in dialogs, less studied setting suffers from data sparsity. We hypothesize and emotion can inform each other, we propose to explore influence of dialog structure topic act prediction. investigate Multi-Task Learning (MTL) approach, where all tasks mentioned above are learned jointly dialog-tailored...
Gamma-aminobutyric acid (GABA) is the predominant amino in litchi pulp, known for its neuroregulatory effects and anti-inflammatory properties. Although previous research has highlighted pro-inflammatory characteristics of thaumatin-like protein (LcTLP), interplay between GABA LcTLP relation to inflammation remains unclear. This study aims explore hepatoprotective pulp-derived extract (LGE) against LcTLP-induced liver mice LO2 cells. In vivo experiments demonstrated that LGE significantly...
Ban-Lan-Gen (BLG) is a traditional Chinese herbal medicine. It has been used for the prevention and treatment of virus-related respiratory diseases such as influenza virus infection. BLG contains some antiviral compounds, but few evidence-based clinical studies have conducted to assess its efficacy against influenza. We assessed effects (including safety) on seasonal in an trial.We randomized, double-blinded, oseltamivir- placebo-controlled, parallel-design trial. A total 177 subjects are...
Hyperlipidemia could cause some serious harm to human health diseases, such as atherosclerosis, coronary heart disease. This study sought investigate the effects of compound Danshen tablet (CDT) on hyperlipidemia induced by a high-fat diet in ApoE-/- mice and related antioxidation, anti-inflammation, anticoagulation, anti-apoptosis mechanisms.The control group (Group 1) comprised 15 male C57BL/6N mice, other 5 groups (Groups 2-6) 75 mice. These were randomly divided into 1 following groups:...
Xinmai 'an tablet has been used to improve myocardial blood supply. Recently, some compounds from its formula have shown that they can treat pulmonary arterial hypertension (PAH).This study investigates the effects of extract (XMA) on PAH and further tests co-therapeutic enhancement with sildenafil (SIL).Pulmonary artery smooth muscle cells were subjected stimulation SIL (12.5 μM) XMA (250 μg/mL) for 48 h. Sprague-Dawley rats randomly grouped into eight groups (n = 8 per group): (I) control...
Starch sodium octenyl succinate (SSOS) and maltodextrin (MD) are commonly used as wall materials to protect bioactive compounds, such essential oils volatiles. In this work, Rimulus Cinamon (RC) Angelica Sinenis (AS) (EOs) were encapsulated in (SSOS/MD) composite capsules via spray drying. The microcapsules characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) thermogravimetric (TG). particle size, Zeta potential, drug loading (DL),...