A5084158470- Polysaccharides and Plant Cell Walls
- Phytochemistry and Biological Activities
- Seed Germination and Physiology
- Natural product bioactivities and synthesis
- Mycorrhizal Fungi and Plant Interactions
- Ginseng Biological Effects and Applications
- Agriculture, Soil, Plant Science
- Polysaccharides Composition and Applications
- Traditional Chinese Medicine Analysis
- Plant tissue culture and regeneration
- Forest, Soil, and Plant Ecology in China
- Plant Pathogens and Fungal Diseases
- Plant Molecular Biology Research
- Pharmacological Effects of Natural Compounds
- Fungal Biology and Applications
- Plant and fungal interactions
- Plant biochemistry and biosynthesis
- Plant-Microbe Interactions and Immunity
- Plant nutrient uptake and metabolism
- Phytochemical Studies and Bioactivities
- Metabolomics and Mass Spectrometry Studies
- Phytoestrogen effects and research
- GABA and Rice Research
- Plant Ecology and Soil Science
- Medicinal Plant Pharmacodynamics Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2024
Huazhong Agricultural University
2021-2023
Ministry of Education of the People's Republic of China
2023
State Administration of Traditional Chinese Medicine of the People's Republic of China
2023
Peking Union Medical College Hospital
2020
State Key Laboratory of Remote Sensing Science
2014-2016
Beijing Normal University
2014-2016
Nanjing Agricultural University
2013
Institute of Medicinal Plant Development
2005-2012
Salvia miltiorrhiza is an important medicinal plant with great economic and value. The complete chloroplast (cp) genome sequence of miltiorrhiza, the first sequenced member Lamiaceae family, reported here. 151,328 bp in length exhibits a typical quadripartite structure large (LSC, 82,695 bp) small (SSC, 17,555 single-copy regions, separated by pair inverted repeats (IRs, 25,539 bp). It contains 114 unique genes, including 80 protein-coding 30 tRNAs four rRNAs. structure, gene order, GC...
Terpenoids are the largest class of plant secondary metabolites and have attracted widespread interest.Salvia miltiorrhiza, belonging to most widely distributed genus in mint family, is a model medicinal with great economic value.Diterpenoid tanshinones major lipophilic bioactive components S. miltiorrhiza.Systematic analysis genes involved terpenoid biosynthesis has not been reported date.Searching recently available working draft miltiorrhiza genome, 40 biosynthesis-related were...
This research is motivated by the increasing threat of urban heat waves that are likely worsened pervasive global warming and urbanization. Different regions city including urban, borderland rural area will experience different levels health risk. In this paper, we propose an improved approach to quantitatively assess Beijing’s risk based on three factors from hazard, vulnerability especially environment which considered as independent factor because land use/cover types have influence...
Salvia miltiorrhiza is a Chinese herb with significant pharmacologic effects because of the bioactive compounds tanshinones and phenolic acids. Methyl jasmonate ( MeJA ) has been used as an effective elicitor to enhance production these compounds. However, molecular mechanism ‐mediated tanshinone salvianolic acid biosynthesis remains unclear. The transcriptional profiles S. leaves at 12 h T12 after elicitation mock‐treated T0 were generated using Illumina deep RNA sequencing ‐seq) strategy...
Abstract Salvia miltiorrhiza is well known for its clinical practice in treating heart and cardiovascular diseases. Its roots, used traditional Chinese medicine materials, are usually brick-red due to accumulation of red pigments, such as tanshinone IIA I. Here we report a S. line (shh) with orange roots. Compared the roots normal plants, contents tanshinones single bond at C-15,16 were increased, whereas those double significantly decreased shh. We assembled high-quality chromosome-level...
Motivated by growing heat-related morbidity and mortality in a warming climate, this paper assesses global heat health risk order to understand the challenges sustainability 21st century, using four Representative Concentration Pathways (RCPs) of HadGEM2-ES climate model five Shared Socio-Economic (SSPs). Factors influencing were reviewed risks estimated based on hazard socio-economic vulnerability. Hazard, vulnerability, particular, populations at different levels, analyzed quantitatively...
Abstract The morbidity and mortality of hand, foot mouth disease (HFMD) are increasing in Beijing, China. Previous studies have indicated an association between incidents HFMD weather factors. However, the seasonal influence these factors on is not yet understood their relationship with enterovirus 71 (EV71) Coxsackie virus A16 (CV-A16) viruses well documented. We analysed 84,502 cases from 2008 to 2011 Beijing explore (average temperature [AT], average relative humidity [ARH], total...
Diabetes is a worldwide severe health issue which causes various complications. This study aimed to evaluate the hypoglycemic effects of Rehmannia glutinosa (RG), Coptis chinensis (CC) alone and their combination on high-fat-diet-induced diabetes in mice via biochemical assays UPLC-Q/TOF-MS-based serum metabolomic analysis. Diabetic KK-Ay were induced by high-fat diet treated for eight weeks, separately with RG, CC positive control drug metformin. Administration RG alone, could decrease...
This study aimed to explore dark septate endophytes (DSE) that may improve the cultivation of medicinal plants in arid ecosystems. We isolated and identified eight DSE species (Acremonium nepalense, Acrocalymma vagum, Alternaria chartarum, chlamydospora, longissima, Darksidea alpha, Paraphoma chrysanthemicola, Preussia terricola) colonizing roots wild licorice (Glycyrrhiza uralensis) desert areas northwest China. Moreover, we investigated osmotic stress tolerance using pure culture, along...
Rhizosphere microbiome adapts their structural compositions to water scarcity and have the potential mitigate drought stress of plants. To unlock this potential, it is crucial understand community responses in interplay between soil properties, management exogenous microbes interference. Inoculation with dark septate endophytes (DSE) (Acrocalymma vagum, Paraboeremia putaminum) Trichoderma viride on Astragalus mongholicus grown non-sterile was exposed drought. were assessed by Illumina MiSeq...
Abstract Background Paris polyphylla var. yunnanensis is an important medicinal plant. Seed dormancy one of the main factors restricting artificial cultivation. The molecular mechanisms seed remain unclear, and little genomic or transcriptome data are available for this Results In study, massive parallel pyrosequencing on Roche 454-GS FLX Titanium platform was used to generate a substantial sequence dataset P. embryo . 369,496 high quality reads were obtained, ranging from 50 1146 bp, with...
This article focuses on the image fusion of high-resolution panchromatic and multispectral images. We propose a new method based Hue-Saturation-Value (HSV) color space model bidimensional empirical mode decomposition (BEMD), by integrating high-frequency component into optimizing BEMD in decreasing sifting time, simplifying extrema point locating more efficient interpolation. has been tested with (SPOT, 10-m resolution) (TM, 28-m resolution). Visual quantitative assessment methods are...
Rehmannia glutinosa, one of the most widely used herbal medicines in Orient, is rich biologically active iridoids. Despite their medicinal importance, no molecular information about iridoid biosynthesis this plant presently available. To explore transcriptome R. glutinosa and investigate genes involved biosynthesis, we massively parallel pyrosequencing on 454 GS FLX Titanium platform to generate a substantial EST dataset. Based sequence similarity searches against public databases, sequences...
Abstract Alkaloids in bulbs of Corydalis ( C. ) yanhusuo are the major pharmacologically active compounds treatment blood vessel diseases, tumors and various pains. However, due to absence gene sequences , genes involved alkaloid biosynthesis their expression during bulb development remain unknown. We therefore established first transcriptome database via Illumina mRNA-Sequencing a RNA composite sample collected at Bulb initiation (Day 0), early enlargement 10) maturation 30). 25,013,630...
Rehmannia glutinosa, a herb of the Scrophulariaceae family, is widely cultivated in Northern part China. The tuberous root has well known medicinal properties; however, yield and quality are threatened by abiotic biotic stresses. Understanding molecular process development may help identify novel targets for its control. In present study, we used Illumina sequencing de novo assembly strategies to obtain reference transcriptome that relevant development. We then conducted RNA-seq...
In the current study, we explored effects of dark septate endophytes (DSE) ( Neocamarosporium phragmitis, Alternaria chlamydospore , and Microascus alveolaris ) on performance rhizosphere soil microbial composition Lycium ruthenicum Murr under drought stress. Differences in plant growth physiological indexes, parameters, different treatments were studied. Three DSE species could form good symbiotic relationships with L. plants, symbionts depended water availability. Inoculation had greatest...
Introduction Licorice ( Glycyrrhiza uralensis Fisch.) is a widely recognized significant form of medicine in China, with long-standing history and extensive usage. It considered the oldest most prevalent herbal China. Currently, licorice market confronted primary challenges mixed genotypes, inconsistent quality, inadequate glycyrrhizic acid content. Methods We conducted field experiments to investigate impact various cultivation locations on growth characteristics, active ingredients,...