A5033029643- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radiation Therapy and Dosimetry
- Epilepsy research and treatment
- Functional Brain Connectivity Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced X-ray and CT Imaging
- Advances in Oncology and Radiotherapy
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Educational Reforms and Innovations
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced X-ray Imaging Techniques
- AI in cancer detection
- Advanced Neuroimaging Techniques and Applications
- Healthcare Education and Workforce Issues
- Cardiac Structural Anomalies and Repair
- Diverse Approaches in Healthcare and Education Studies
- Lung Cancer Research Studies
- Advanced Fluorescence Microscopy Techniques
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroblastoma Research and Treatments
- Optical Systems and Laser Technology
Zunyi Medical University
2020-2024
University of Washington
2024
The University of Texas MD Anderson Cancer Center
2018-2023
The University of Texas Health Science Center at Houston
2018-2023
University of Houston
2023
Affiliated Hospital of Guizhou Medical University
2022
University of Massachusetts Chan Medical School
2017
Anderson University - South Carolina
2017
Worcester Polytechnic Institute
2017
Treatment of non-small cell lung cancer with proton therapy allows for delivery high radiation dose while sparing critical normal tissue structures compared to conventional photon therapy. However, there are currently no established clinical endpoints study the biological effect between these modalities. Computed tomography (CT) imaging extraction ventilation through deformable image registration 4DCTs and may provide information on imaging-based functional changes in lung. We hypothesize...
Rationale and ObjectivesThe white matter (WM) functional network changes offers insights into the potential pathological mechanisms of certain diseases, alterations WM in idiopathic generalized epilepsy (IGE) remain unclear. We aimed to explore topological characteristics childhood IGE using resting-state Magnetic resonance imaging (MRI) T1-weighted images.MethodsA total 84 children (42 42 matched healthy controls) were included this study. Functional structural MRI data acquired construct a...
Purpose Response assessment of radiotherapy for the treatment intrahepatic cholangiocarcinoma (IHCC) across longitudinal images is challenging due to anatomical changes. Advanced deformable image registration (DIR) techniques are required correlate corresponding tissues time. In this study, accuracy five commercially available DIR algorithms in four planning systems (TPS) was investigated with posttreatment follow‐up response or re‐treatment purposes. Methods Twenty‐nine IHCC patients...
Benign childhood epilepsy with centrotemporal spikes (BECTS) affects brain network hierarchy and cognitive function; however, itremainsunclearhowhierarchical changeaffectscognition in patients BECTS. A major aim of this study was to examine changes the macro-network function BECTS its potential contribution function.
A large number of surveys have been sent to the medical physics community addressing many clinical topics for which physicist is, or may be, responsible. Each survey provides an insight into practice relevant community. The goal this study was create a summary these giving snapshot patterns. Surveys used in were created using SurveyMonkey and distributed between February 6, 2013 January 2, 2018 via MEDPHYS MEDDOS listserv groups. format included questions that multiple choice free response....
Abstract Aims Alterations in neuronal activity and cerebral hemodynamics have been reported idiopathic generalized epilepsy (IGE) patients, possibly resulting neurovascular decoupling; however, no neuroimaging evidence confirmed this disruption. This study aimed to investigate the possible presence of decoupling its clinical implications childhood IGE using resting‐state fMRI arterial spin labeling imaging. Methods patients healthy participants underwent imaging calculate degree centrality...
Most brain SPECT imaging procedures are currently being performed using general-purpose systems which unable to fully take advantage of the use clinically available agents. We designing a novel multi-detector, multi-pinhole modular dedicated system called AdaptiSPECT-C improve sensitivity and resolution, address static dynamic needs. The aim this study was evaluate axial angular sampling sufficiency preliminary design simulation XCAT customized Defrise phantom. simulator as well image...
PurposeTo determine the dosimetric limitations of daily online adaptive pancreas stereotactic body radiation treatment by using an automated dose escalation approach.Methods and MaterialsWe collected 108 planning computed tomography (CT) scans from 18 patients (18 × 6 CT scans) who received 5-fraction at MD Anderson Cancer Center. Dose metrics original non-dose-escalated clinical plan (non-DE), dose-escalated created on (DE-ORI), therapy (DE-ART) were analyzed. We developed a dose-escalation...
Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas (UCOGCP) is a rare pancreatic tumor that accounts for <1% all primary malignant tumors. Although considered variant ductal adenocarcinoma, there are substantial differences in clinicopathological characteristics between UCOGCP and adenocarcinoma. Imaging examinations useful making correct diagnosis, providing reasonable effective surgical treatment regimen; however, imaging require further investigation. The present...
523 Background: Data on the safety and efficacy of external beam radiation (EBRT) after Yttrium-90 (Y-90) radioembolization for hepatocellular carcinoma (HCC) is limited. We report our experience using EBRT to treat HCC patients who were previously treated with Y-90. Methods: analyzed 31 received following Y-90 treatment. Eighteen photon therapy (40-50 Gy in 5 fractions), thirteen proton (42-67.5 15 fractions). Twenty-four underwent segmentectomies, while seven lobar The median administered...
Conventional radiation therapy of brain tumors often produces cognitive deficits, particularly in children. We investigated the potential efficacy merging Orthovoltage X-ray Minibeams (OXM). It segments beam into an array parallel, thin (~0.3 mm), planar beams, called minibeams, which are known from synchrotron x-ray experiments to spare tissues. Furthermore, slight divergence OXM make individual minibeams gradually broaden, thus with their neighbors at a given tissue depth produce solid...
Successful generation of biomechanical-model-based deformable image registration (BM-DIR) relies on user-defined parameters that dictate surface mesh quality. The trial-and-error process to determine the optimal can be labor-intensive and hinder DIR efficiency clinical workflow.
Re-planning for four-dimensional computed tomography (4DCT)-based lung adaptive radiotherapy commonly requires deformable dose mapping between the planning average-intensity image (AVG) and newly acquired AVG. However, such AVG-AVG registration (DIR) lacks accuracy assessment. The current work quantified compared geometric accuracies of DIR corresponding phase-phase DIRs, subsequently investigated clinical impact on mapping.Hybrid intensity-based DIRs were performed mid-treatment 4DCTs 28...
Cardiac myxoma is a common benign primary intracardiac tumor in the general population, and it generally characterized as tumor, morbidity of biatrial low. Cases young patients are extremely rare. Furthermore, severe complications cardiac myxoma, such cerebral embolism, can have fatal consequences. Imaging effectively assist making correct diagnosis safe efficient surgical treatment plan. In this case report, we describe unique woman who presented with accompanied by pulmonary embolism...
SPECT imaging of dopamine transporters (DAT) in the brain is a widely utilized study to improve diagnosis Parkinsonian syndromes, where conventional (parallel-hole and fan-beam) collimators on dual-head scanners are commonly employed. We have designed multi-pinhole (MPH) collimator performance DAT imaging. The MPH focuses striatum hence offers better trade-off for sensitivity spatial resolution than within this clinically most relevant region Our original design consisted 9 pinholes with...
A next-generation, adaptive, brain-imaging, single photon emission computed tomography system is currently under development at the Universities of Arizona and Massachusetts. The proposed multi-pinhole based modular gamma camera configuration enables acquisition "quasi-vertex" views i.e., close to vertex. This study concerned with understanding how activity inferior brain will influence these ultimately, reconstruction volume interest. Analytical models can provide some measure detected...
Studies have demonstrated that adults with idiopathic generalized epilepsy (IGE) functional abnormalities; however, the neuropathological pathogenesis differs between and children. This study aimed to explore alterations in cerebral blood flow (CBF) connectivity (FC) comprehensively elucidate mechanisms of IGE children.We obtained arterial spin labeling (ASL) resting state magnetic resonance imaging data 28 children 35 matched controls. We used ASL determine differential CBF regions IGE. A...
Earlier, we proposed an inexpensive method to improve the performance of conventional dual-head SPECT systems for I-123 dopamine transporter (DAT) imaging Parkinson Disease. In this approach, collimator on one head is replaced with a multi-pinhole (MPH) while retaining other head, thus enabling combined MPH/Parallelbeam (or Fanbeam) acquisition. The original MPH design consisted 9 apertures rectangular entrance/exit ports covering cylindrical volume interest (VOI) around striatum minimal...
Hematoma expansion (HE) is an important risk factor for poor prognosis in patients with hypertensive intracerebral hemorrhage. This study aimed to establish a nomogram model predicting HE, and evaluate the model.The clinical data plain computed tomography (CT) scan signs of 341 hemorrhage were retrospectively analyzed. According development divided into HE group (100 cases) non-HE (241 cases). The CT these two groups compared. Variables that had statistically significant differences included...
A mechanical design is reported for constructing a multi-pinhole (MPH) collimator that will be used with fanbeam high spatial resolution and sensitivity imaging of the striatal region patients suspected having Parkinson's disease. The strategy was to alter an existing commercial pinhole by adding MPH components while keeping portion attaches head gamma-camera. array consists nine apertures focused at common point center brain their entrance exit ports such no overlapping occurs projections...
Abstract: Primary neuroendocrine tumors (NETs) in the heart are exceptionally rare. Here, we report a case found at our hospital of 51-year-old woman with primary left ventricular NET. The patient presented non-causal recurrent diarrhea for 2 years, abdominal pain, and vomiting. Endoscopy revealed chronic proctitis duodenal ulcer but no explanation clinical symptoms. Comprehensive cardiovascular tests were conducted, mass measuring 26 mm × 41 30 was detected ventricle. underwent complete...