A5101576115- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac pacing and defibrillation studies
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Cardiovascular Effects of Exercise
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced X-ray and CT Imaging
- Cardiovascular Disease and Adiposity
- Helicobacter pylori-related gastroenterology studies
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Viral Infections and Immunology Research
- Cardiac Valve Diseases and Treatments
- Veterinary medicine and infectious diseases
- Solar Radiation and Photovoltaics
- Solar Thermal and Photovoltaic Systems
- Microscopic Colitis
- solar cell performance optimization
- Cardiovascular Health and Risk Factors
Tokyo Women's Medical University
2007-2025
Saitama Medical University
2021
Nippon Medical School
2011-2019
Aoyama Hospital Tokyo Women’s Medical University
2015-2017
Brigham and Women's Hospital
2012-2016
Cardiac involvement is an important prognostic factor in sarcoidosis, and cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) can facilitate the identification of cardiac sarcoidosis (CS). In patients CS, we investigated LGE characteristics their relationship left ventricular (LV) function to identify those unique severely reduced LV function. We also between duration sarcoidosis.We retrospectively evaluated 19 CS diagnosed according 2006 revised guidelines...
Human skin contains the following two distinct DC subsets: (i) Langerhans cells (LCs), expressing Langerin but not DC-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), are predominantly localized in epidermis; and (ii) dermal DCs, DC-SIGN Langerin, observed mainly dermis. It is known whether localization epidermis provides cues for LC differentiation. Here, we show that E-cadherin expressed by epidermal keratinocytes (KCs) crucial differentiation of LCs. Monocytes...
Helicobacter pylori infection is associated with several autoimmune diseases, in which autoantibody-producing B cells must be activated. Among these cells, CD5-positive B-1a from BALB/c mice were confirmed to secrete autoantibodies when cocultured purified H. urease the absence of T cells. To determine mechanisms for autoantibody production, sorted murine spleen and stimulated either or coated onto plates (referred hereafter as plate-coated pylori), production was measured by enzyme-linked...
<h3>Objective</h3> Plasma cancer antigen (CA)-125 is a tumour marker recently shown to be associated with systolic heart failure and new-onset atrial fibrillation (AF) after myocardial infarction. However, no reports have described the relationship between CA-125 AF in healthy postmenopausal women. The aim of present study was evaluate <h3>Methods</h3> Between 2005 2015, 2086 women, including 1012 visited our hospital for annual health check-ups. We excluded patients dysfunction, chronic...
In patients with small hearts, the Quantitative Gated single-photon emission computed tomography (SPECT) (QGS) program frequently underestimates left ventricular (LV) end-systolic volume (ESV) and overestimates ejection fraction (EF). A newly developed cardiac software program, cardioREPO/EXINI heart (cREPO), has been proposed to more accurately quantify hearts using active shape modeling a volume-dependent edge correction algorithm for LV delineation. The aim of this study was validate...
Diagnosis and evaluation of cardiac sarcoidosis (CS) are mainly based on the combined use magnetic resonance imaging (CMR) 18F fludeoxyglucose positron emission tomography (FDG). Though these modalities can detect pathological feature disease, assessment has not been fully examined. Multimodality image fusion is known to be useful for further comprehension, while most interpretation performed with a side by comparison in clinical routine. We investigated similarity discrepancy active...
Helicobacter pylori (H. pylori) urease is a key protein for persistent infection of the bacteria in stomach. Although H. generally induce anti-H. pylori-specific antibodies (Abs), these Abs do not usually work eradication or prevention infection. In our previous study, we identified linear epitope composed 19-mer peptides termed UB-33, CHHLDKSIKEDVQFADSRI, within large subunit urease. Anti-UB-33-specific neutralized enzymatic activity vitro. present evaluated effect immunization BALB/c mice...
Background:We investigated the association between left ventricle ejection fraction (LVEF) and vortex flow (VF), whether cardiac resynchronization therapy (CRT) response can be predicted using VF mapping (VFM) in patients with dilated cardiomyopathy (DCM).