A5041244956- Lipoproteins and Cardiovascular Health
- Superconducting Materials and Applications
- Magnetic confinement fusion research
- Particle accelerators and beam dynamics
- Obstructive Sleep Apnea Research
- Cancer, Lipids, and Metabolism
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Ionosphere and magnetosphere dynamics
- Spacecraft and Cryogenic Technologies
- Atmospheric Ozone and Climate
- Hormonal Regulation and Hypertension
- Acute Kidney Injury Research
- Physics of Superconductivity and Magnetism
- Plasma Diagnostics and Applications
- Renal and Vascular Pathologies
- Cardiovascular Syncope and Autonomic Disorders
- Cholesterol and Lipid Metabolism
- Acute Myocardial Infarction Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Refrigeration and Air Conditioning Technologies
- Angiogenesis and VEGF in Cancer
- Cardiac Ischemia and Reperfusion
- Respiratory Support and Mechanisms
- Integrated Circuits and Semiconductor Failure Analysis
Tokyo Women's Medical University
2014-2023
National Hospital Organization
2011-2022
Kyoto Medical Center
2020-2022
Aoyama Hospital Tokyo Women’s Medical University
2013-2020
Tokyo Women's Medical University Hospital
2013-2019
Mayo Clinic in Arizona
2019
Sleep Comprehensive Care Clinic Yoyogi
2019
Kyoto University
2002-2018
National Institute for Fusion Science
2004-2015
The Graduate University for Advanced Studies, SOKENDAI
2015
Abstract Noninvasive measurement of the distribution and oxygenation state hemoglobin (Hb) inside tissue is strongly required to analyze tumor-associated vasculatures. We developed a photoacoustic imaging (PAI) system with hemispherical-shaped detector array (HDA). Here, we show that PAI HDA revealed finer vasculature, more detailed blood-vessel branching structures, morphological vessel characteristics compared MRI by use breast shape deformation their fused image. Morphologically abnormal...
We hypothesized that a small molecule CXCR4 antagonist, AMD3100 (AMD), could augment the mobilization of bone marrow (BM)-derived endothelial progenitor cells (EPCs), thereby enhancing neovascularization and functional recovery after myocardial infarction. Single-dose AMD injection administered onset infarction increased circulating EPC counts vascularity, reduced fibrosis, improved cardiac function survival. In mice transplanted with traceable BM cells, BM-derived cell incorporation in...
Background— Estradiol (E 2 ) modulates the kinetics of circulating endothelial progenitor cells (EPCs) and favorably affects neovascularization after ischemic injury. However, roles estrogen receptors α (ERα) β (ERβ) in EPC biology are largely unknown. Methods Results— In response to E , migration, tube formation, adhesion, estrogen-responsive element–dependent gene transcription activities were severely impaired EPCs obtained from ERα-knockout mice (ERαKO) moderately ERβKO EPCs. The number...
Abstract Aims Loop diuretics are first‐line medications for congestive heart failure (CHF); however, they associated with serious adverse effects, including decreased renal function, and sympathetic nervous renin–angiotensin system activation. We tested whether tolvaptan, a vasopressin V2‐receptor antagonist, could reduce unfavourable furosemide‐induced effects during CHF treatment. Methods results Sixty patients emergently hospitalized owing to CHF‐induced dyspnea were randomly assigned...
An impressive and efficient improvement in the classical scale-space analysis was proposed by Perona Malik (1990) where they describe diffusion process known as Perona-Malik (PM) equation. Despite illposed nature of PM equation, many its applications could be carried with success signal processing field. On other hand Weickert Benamouda (1997) proved regularization equation describing analyzing a model on semidiscrete system. In this article we present regularized for image segmentation. We...
Background— CXC-chemokine receptor 4 (CXCR4) regulates the retention of stem/progenitor cells in bone marrow (BM), and CXCR4 antagonist AMD3100 improves recovery from coronary ligation injury by mobilizing BM to peripheral blood. Thus, we investigated whether also ischemia/reperfusion injury, which more closely mimics myocardial infarction patients, because blood flow is only temporarily obstructed. Methods Results— Mice were treated with single subcutaneous injections (5 mg/kg) or saline...
We analysed the vascular morphology of palm using a photoacoustic tomography (PAT) instrument with hemispherical detector array. The three-dimensional (3D) blood vessels was determined noninvasively. Overall, 12 females and 11 males were recruited as healthy volunteers. Their ages distributed almost evenly from 22 to 59 years. In all cases, many networks observed just beneath skin be veins anatomically. To analyse major arteries, layer containing subcutaneous venous network removed image....
Abstract Aims The association between kinetics of blood urea nitrogen (BUN) levels in hospital and cardiovascular outcomes patients with acutely decompensated congestive heart failure (HF) is unclear. We aimed to estimate the impact changes BUN level during hospitalization on clinical prognosis acute HF. Methods results A total 353 consecutive that were urgently hospitalized due HF discharged alive divided into four subgroups depending their at admission discharge, using a cut‐off 21.0...
Rationale : Recent reports have demonstrated that signals from vascular endothelial cells are necessary for organogenesis may precede vasculogenesis. However, the origin of these neovascular in regenerating tissue has not been clarified. Objective Here we tested hypothesis adult neural stem (NSCs) can differentiate into lineage, as well process collaborative organogenesis. Methods and Results NSCs, clonally isolated mouse brain, were shown to develop smooth muscle phenotypes vitro. To...
We report on the characteristics of electronegative plasma in a large-scale hydrogen negative ion (H−) source. The measurement has been made with time-resolved Langmuir probe installed beam extraction region. H− density is monitored cavity ring-down system to identify electrons charges. electron-saturation current decreases rapidly after starting seed Cs, and ion-ion observed steps down during electron jumps up correspondingly. time integral decreasing charge agrees well collected probe....
In March 1998, the LHD project finally completed its eight year construction schedule. is a superconducting (SC) heliotron type device with R = 3.9 m, ap 0.6 m and B 3 T, which has simple continuous large helical coils. The major mission of to demonstrate high potential currentless helical-toroidal plasmas, are free from current disruption have an intrinsic for steady state operation. After intensive physics design studies in 1980s, necessary programmes SC engineering R&D was carried out, as...
Numerous endothelial progenitor cell (EPC)-related investigations have been performed in mouse experiments. However, defined characteristics of cultured EPC not examined. We focused on fast versus slow adherent population bone marrow mononuclear cells (BMMNCs) culture and examined their characteristics. After 24 h-culture BMMNCs, attached (AT) floating (FL) were further differentiation medium separately. Immunological molecular analyses exhibited more endothelial-like less...
Abstract Background Oral myofunctional therapy (MFT) is an effective treatment for mild‐to‐moderate obstructive sleep apnoea (OSA) in middle‐aged patients. However, few reports have described its use elderly patients with moderate and severe OSA. Moreover, no studies examined the relationship between changes tongue pressure MFT severity of Objective We conducted interventional study using to evaluate effect on middle‐to‐senior‐aged or OSA compared apnoea‐hypopnea index (AHI) pressure....
The display image on the monitor can be reconstructed by receiving and analyzing unexpected electromagnetic noise emanated from a personal computer system. This fact is one of information leakage threats in security. Therefore, it important to evaluate prevent caused noise. In this paper, we propose measurement method signal, which contained computer. signal correlated with RGB constructing image, because reconstruct similar image. order detect displayed vertical stripes pattern specific...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Y. Takeiri, K. Tsumori, M. Osakabe, Ikeda, Nagaoka, H. Nakano, Kisaki, O. Kaneko, E. Asano, T. Kondo, Sato, Shibuya, S. Komada, Sekiguchi; Development of intense hydrogen-negative-ion source for neutral beam injectors at NIFS. AIP Conf. Proc. 8 February 2013; 1515 (1): 139–148. https://doi.org/10.1063/1.4792780...
<h3>Objective</h3> Plasma cancer antigen (CA)-125 is a tumour marker recently shown to be associated with systolic heart failure and new-onset atrial fibrillation (AF) after myocardial infarction. However, no reports have described the relationship between CA-125 AF in healthy postmenopausal women. The aim of present study was evaluate <h3>Methods</h3> Between 2005 2015, 2086 women, including 1012 visited our hospital for annual health check-ups. We excluded patients dysfunction, chronic...
It is known that the display image on a personal computer with monitor can be reconstructed by receiving electromagnetic noise. Recently, concern about information leakage in caused noise has increased from aspect of security. In present study, input button key operations touch screen monitors was investigated experimentally using received The experimental results revealed touched identified image. addition, origin discussed based reconstruction principle