A5055600695- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Tracheal and airway disorders
- Gastrointestinal disorders and treatments
- Autoimmune Bullous Skin Diseases
- Congenital Diaphragmatic Hernia Studies
- Gastrointestinal Tumor Research and Treatment
- Multiple and Secondary Primary Cancers
- Dysphagia Assessment and Management
- Metastasis and carcinoma case studies
- Cardiac, Anesthesia and Surgical Outcomes
- Oral and gingival health research
- Adrenal and Paraganglionic Tumors
- Intensive Care Unit Cognitive Disorders
- Lymphatic Disorders and Treatments
- Occupational and environmental lung diseases
- Gallbladder and Bile Duct Disorders
- Mycobacterium research and diagnosis
- Colorectal and Anal Carcinomas
- Skin and Cellular Biology Research
- Combustion and Detonation Processes
- Apelin-related biomedical research
Shizuoka Cancer Center
2019-2023
Shizuoka Medical Center
2020
Keio University
2011-2018
keiyu Hospital
2015-2018
Toho University
2016
Stanford University
1991
Obesity is a known risk factor for complications after digestive surgery. Body mass index (BMI) commonly used as an of obesity but does not always reflect the degree obesity. Although some studies have shown that high visceral fat area (VFA) associated with poor outcomes in surgery, few examined relationship between VFA and total gastrectomy. In this study, we demonstrated more useful than BMI predicting gastrectomy.Seventy-five patients who underwent gastrectomy gastric cancer were enrolled...
Spontaneous perforation of the bile duct in adults is very rare, particularly cases accompanied by retroperitoneal biloma. We report a patient with biloma due to spontaneous left hepatic duct.An 82-year-old man was admitted our institution abdominal pain and high fever. He had tenderness at epi-mesogastrium. Computed tomography showed several stones gall bladder common (CBD) few ascites. A substantial amount fluid collected from dorsal stratum duodenum pancreas head right paracolic gutter...
Little is known about the clinical characteristics and health-related quality of life (HQOL) elderly patients with pulmonary Mycobacterium avium complex (pMAC) disease.To evaluate HQOL using 36-Item Short-Form Health Survey St George's Respiratory Questionnaire (SGRQ) to investigate predictors changes among pMAC disease.This prospective cohort registry was conducted at Keio University Hospital, Tokyo, Japan, between May 2012 July 2015 included 84 disease aged 75 years who had completed...
Purpose/Aim: We performed a randomized, prospective animal study to investigate whether inhibiting the renin-angiotensin system with (pro)renin receptor blocker (PRRB) prevents acute lung injury (ALI) in rodent model. Materials: used Thirty-six male Sprague-Dawley rats. administered lipopolysaccharide (LPS; 2 mg/kg) intratracheally or without PRRB pretreatment (1 mg/kg/d). Methods: bronchoalveolar lavage (BAL) and removal at 4 h after LPS administration measured levels of inflammatory...
Recent comprehensive mutation analyses have revealed a relatively small number of driver mutations in esophageal cancer, implicating limited molecular targets, most which are also implicated squamous cell carcinoma.In this study, we investigated genetic alterations 44 carcinomas (ESCC) and 8 adenocarcinomas (EAC) from Japanese patients as potential based on data the version The Genome Atlas (JCGA).Esophageal cancer was characterized by TP53 somatic ESCC (39/44, 88.6%) EAC (5/8, 62.5%). In...
Perforation of the abdominal esophagus caused by nasogastric tube (NGT) intubation has been rarely reported in adults.A 73-year-old man was admitted to our hospital with pneumonia. He had bedridden long-term and previously undergone a gastrectomy for gastric ulcer. Since admission prolonged, he required enteral feeding because his inability swallow, NGT inserted blindly. The next day, high fever pain. Abdominal computed tomography scan revealed that through wall into cavity. In emergency...
Pentoxifylline (PTX), a methylxanthine, can suppress polymorphonuclear leukocyte (PMN) activation and attenuate sepsis-induced acute lung injury. We investigated whether PTX prevents non-PMN-dependent First we studied four groups of granulocyte-depleted guinea pigs (control, PTX, Escherichia coli, E. coli + PTX). Lung injury was assessed by wet-to-dry weight (W/D) ratio tissue-to-plasma 125I-albumin (albumin index, AI). The group showed significant increase in the W/D AI compared with...
Acquired dermal melanocytosis (ADM) is a relatively rare, but well‐described disease among adolescent to middle‐aged East Asian women, particularly those of Japanese and Chinese descent. Clinically, ADM manifests as multiple punctate greyish‐brown pigmented areas 1–3 mm in diameter occurring on both sides the forehead zygomatic region. The subtype affecting face extremities extremely rare even women. We describe three patients with (ADMFE) their characteristic clinical features. All were...
Esophagectomy is a highly invasive procedure for patients aged > 70 years. Here, we compared the actual nutritional status of older and younger who underwent esophagectomy.A total 118 radical esophagectomy between April 2013 December 2016 were enrolled divided into two groups based on age: group A (n = 41; ≥ years) B 77; < years). Data pertaining to body mass index variables (albumin; cholesterol; cholinesterase; prealbumin) retrospectively analyzed preoperatively at 3, 6, 12 months...
Pedicled jejunal flap can be utilized with various tips for esophageal reconstruction in patients a history of gastrectomy or those who have undergone synchronous esophagogastrectomy. However, the rate anastomosis leakage is high; therefore, we considered evaluation blood flow remnant esophagus indocyanine green setting site.
Giant inguinal hernia is unusual, and duodenal rupture accompanying it particularly very rare significantly hard to manage surgically. An 81-year-old man was admitted our institution with upper abdominal pain. He had tenderness of the mid abdomen a bilateral large but he did not have pain in inguinal–scrotal area. Computed tomography (CT) showed slight dilatation small bowel stomach. There were no remarkable signs incarceration hernia. Therefore, internal ward. On second day hospital,...
Background: Radiation monotherapy effectively relieves symptoms of esophageal cancer. Many studies have reported relief from dysphagia with this treatment; however, the degree is subjective. On other hand, length outpatient management objective. In study, we investigated how radiation can contribute to helping elderly patients cancer remain as outpatients.
One cause of anastomotic leakage after radical esophagectomy is blood flow insufficiency at the cervical anastomosis site. .Eighteen patients, who underwent with gastric tube reconstruction, were studied. The regional tissue oxygen saturation (rSO2) was measured tip (point pre 0) and 2, 4, 6 cm on distal side 1, 3, respectively) before raised to site through retrosternal route. After that, rSO2 tip, 2 4 (points post 0, 2), actual AN), chest skin as an indicator whole-body oxygenation....