A5006296860- Probiotics and Fermented Foods
- Gut microbiota and health
- Listeria monocytogenes in Food Safety
- GABA and Rice Research
- Food Safety and Hygiene
- Food Quality and Safety Studies
- Clostridium difficile and Clostridium perfringens research
- Protein Hydrolysis and Bioactive Peptides
- Soybean genetics and cultivation
- Diet and metabolism studies
- Optical Imaging and Spectroscopy Techniques
- Genomics and Phylogenetic Studies
- Enterobacteriaceae and Cronobacter Research
- Agriculture, Soil, Plant Science
- Animal Nutrition and Physiology
- Genetics, Aging, and Longevity in Model Organisms
- Essential Oils and Antimicrobial Activity
- Non-Invasive Vital Sign Monitoring
- Hemodynamic Monitoring and Therapy
- Pharmacological Effects of Natural Compounds
- Agricultural Systems and Practices
- Echinoderm biology and ecology
- Sirtuins and Resveratrol in Medicine
- Microbial Metabolites in Food Biotechnology
- Ginseng Biological Effects and Applications
National Institute of Biological Resources
2023-2024
Children's Hospital of Philadelphia
2023
Jeonju University
2021-2022
Jeonbuk National University
2018-2021
Microbial Institute for Fermentation Industry
2020
Rural Development Administration
2017-2018
Instituto de Ciencias Agrarias
2018
Chonnam National University
2013-2016
The aim of this study was to evaluate the functional properties lactic acid bacteria from various sources and identify strains for use as probiotics. Ten Lactobacillus were selected their such bile tolerance, resistance, cholesterol assimilation activity, adherence HT-29 cells assessed determine potential sp. JNU 8829, L. casei MB3, sakei MA9, CH8, acidophilus M23 found show full tolerance 0.3% acid. All without most acid-tolerant strains. After incubating at pH 2.5 2 h, viability decreased...
Mammalian milk including microRNAs (miRNAs) as a novel class of noncoding RNAs, that can be transferred to infants and it plays on critical role in biological functions such immune regulation development. However, the origin functional importance milk-derived miRNAs are still undetermined. This study applied RNA sequencing explore featured profiles miRNA expression colostrum mature milk-originated exosomes from human, bovine, caprine milk. These dietary exosome-derived highly conserved...
Effect of L. rhamnosus IDCC3201 on the skeletal muscle atrophy process by regulating metabolomic and gut microbiome alterations.
Soybeans are an important crop for agriculture and food, resulting in increase the range of its application. Recently, soybean leaves have been used not only food products but also beauty industry. To provide useful global metabolite information on development soy-based products, we investigated metabolic evolution cultivar-dependent variation cultivated (Glycine max) semiwild (G. gracilis) soybean, through a 1H NMR-based metabolomics approach, as they grew from V (vegetative) 1 to R...
In this study, we investigated the relation of probiotic activity Lacticaseibacillus rhamnosus strain GG (LGG) and expression microRNA to immune response longevity in Caenorhabditis elegans host model. First, evaluated survival rate C. due LGG exposure bacterial colonization intestine. Next, mRNA miRNA was analyzed for 24 h using microarray. After , colonized observed intestines induced extend lifespan. Moreover, persistent intestine significantly enhanced resistance exposed both pathogenic...
Deer antler velvet is widely used in traditional medicine for its anti-aging, antioxidant, and immunity-enhancing effects. However, few studies have reported on the discovery of probiotic strains deer fermentation to increase functional ingredient absorption. This study evaluated ability lactic acid bacteria enhance concentrations bioactive molecules (e.g., sialic gamma-aminobutyric [GABA]) extracts velvet. Seventeen Lactobacillus spp. that were isolated from kimchi infant feces, including...
Clostridium difficile infection (CDI) is the main cause of hospital-acquired diarrhea that can colitis or even death. The medical-treatment cost and deaths caused by CDI are increasing annually worldwide. New approaches for prevention treatment these infections needed, such as use probiotics. Probiotics, including Bifidobacterium spp. Lactobacillus, microorganisms confer a health benefit to host when administered in adequate amounts. effect longum ATCC 15707 on infectious disease C. 027 was...
Dry aging is a traditional method that improves meat quality, and diverse microbial communities are changed during the process. Lactic acid bacteria (LAB) widely present in fermented foods has many beneficial effects, such as immune enhancement maintenance of intestinal homeostasis. In this study, we conducted metagenomic analysis to evaluate changes composition dry-aged beef. We found lactic bacterial strains were abundant beef including Lactobacillus sakei Enterococcus faecalis....
Objective: To evaluate the effect of ethyl acetate fraction derived from Sargassum pallidum extract against particulate matter (PM)-induced oxidative stress and inflammation in HaCaT cells zebrafish. Methods: zebrafish were used to protective effects PM-induced inflammation. The production nitric oxide (NO), intracellular ROS, prostaglandin E 2 (PGE ), pro-inflammatory cytokines, expression levels COX-2, iNOS, NF-κB evaluated cells. Furthermore, NO, lipid peroxidation assessed PM-exposed...
Abstract Clostridium difficile infection (CDI) is the most prevalent cause of health‐care‐associated infections. CDI‐related health‐care costs and deaths are both increasing annually on a global scale. C. have been reported in food products Canada, Europe, United States; however, systematic transmission between humans animals yet to be understood. Because limitations current therapeutic options, there need for development new patient treatments. Epigallocatechin gallate (EGCG) major catechin...
In the current study, probiotic potential of approximately 250 strains lactic acid bacteria (LAB) isolated from piglet fecal samples were investigated; among them Lactobacillus plantarum strain JDFM LP11, which possesses significant potential, with enhanced acid/bile tolerance, attachment to porcine intestinal epithelial cells (IPEC-J2), and antimicrobial activity. The genetic characteristics LP11 explored by performing whole genome sequencing (WGS) using a PacBio system. circular draft have...
Many fermented foods are known to have beneficial effects on human and animal health, offering anti-aging immunomodulatory benefits host. Microorganisms contained in the provide metabolic products possibly improving host health. However, despite of a number studies functional foods, isolation identification effective bacterial strains still progress. The objective this study was isolate candidate various Korean traditional including ganjang, gochujang, doenjang, jeotgal, evaluate their host,...
Listeria monocytogenes is a major cause of serious foodborne illness in the dairy foods. Although Caenorhabditis elegans model well established as virulence pathogenic bacteria, its application on L. critically unclear. The objective this study was to carry out an evaluation toxicity using C. nematode simple host model. We found that nematodes have high susceptibility infection, consequence accumulation bacteria worms' intestine. However, innocua, which known be non-toxic, not accumulate...
Probiotics, as living microorganisms, exert health benefits to the host by alleviating excess inflammation through modulating immune system and establishing intestinal homeostasis. In this study, we evaluated probiotic characteristics alleviatory effects of Bacillus amyloliquefaciens isolated from traditional Korean fermented foods. The strains withstood acidic environment digestive process, extended lifespan Caenorhabditis elegans, enhanced pmk-1 expression. However, only B. SCGB1 could...
The aim of the present study was to investigate efficacy probiotic yoghurt Lactobacillus rhamnosus GG (LGG) in treatment Irritable bowel syndrome (IBS). Eighty‐three IBS patients yielded data be analysed from this 9‐week, placebo‐controlled, double‐blind and randomized trial. consumed either a LGG‐containing (treatment group; n = 44) or placebo ( 39) twice daily for 6 weeks. results indicate that effective alleviating some symptoms resulted slight changes certain gut microbiota. Probiotic...
Raw milk acts as a mediator of major foodborne pathogenic bacterial infections. However, the sources pathogens that contaminate are often unclear. This study assessed prevalence sanitary quality-indicating bacteria (total aerobic bacteria, psychrotrophic coliform, and yeast/molds), including seven pathogens, in dairy farm environment processing plant Korea. The microbiological analysis showed few sites, such vat bottoms, room floors, drain holes, niches, high microbial loads most farms....
Depression is a kind of mood disorder characterized by decline in motivation, interest, attention, mental activity, and appetite. Although depression caused variety causes, including genetic, endocrine environmental stress, mild has been reported to improve with diet. Therefore, various type food sources functional nutritional supplement are required treat the depressive patients. Cheese contains bioactive peptides that have beneficial effects on host health. In particular, Jersey milk...
Cardiopulmonary bypass (CPB) provides cerebral oxygenation and blood flow (CBF) during neonatal congenital heart surgery, but the impacts of CPB on brain oxygen supply metabolic demands are generally unknown. To elucidate this physiology, we used diffuse correlation spectroscopy frequency-domain optical to continuously measure CBF, extraction fraction (OEF), metabolism (CMRO2) in 27 swine before, during, up 24 h after CPB. Concurrently, sampled microdialysis biomarkers distress...
The purpose of this study was to investigate the main source contamination dried red pepper by assessing microbial loads on peppers, washing water, machines, harvesting containers, and worker gloves that had come in contact with pepper. To estimate loads, indicator bacteria (total bacteria, coliform Escherichia coli) pathogenic (E. coli O157:H7, Salmonella spp., Listeria monocytogenes, Clostridium perfringens) were enumerated. results showed numbers increased significantly after peppers...
Objective: To evaluate the effects of Catalpa bignonioides fruit extract on promotion muscle growth and muscular capacity in vitro vivo. Methods: Cell viability was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. proliferation assessed a 5-bromo-2’-deoxyuridine (BrdU) assay kit. Western blot analysis performed to determine protein expressions related factors. The were investigated mice treadmill exhaustion test whole-limb grip strength Chemical composition...
We demonstrate theoretical methods to correct diffuse correlation spectroscopy estimation of cerebral blood flow for hematocrit variation in a study neonatal swine during cardiopulmonary bypass.
Objective The rich botanical biodiversity resulting from diverse climates and geographical distinctiveness offers a plethora of biological resources that can be pivotal in developing innovative biomaterials. This investigation sought to evaluate the functional properties indigenous Korean plant species. Methods Forty-six plants during year-long expedition across inhabited uninhabited islands were collected. specimens divided into 5 parts (flower, fruit, stem, leaf, whole body) subjected...