Yongyan Zhang

ORCID: 0000-0001-6777-7808
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About
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Research Areas
  • Plant tissue culture and regeneration
  • Plant-Microbe Interactions and Immunity
  • Plant Pathogens and Fungal Diseases
  • Plant Gene Expression Analysis
  • Plant Molecular Biology Research
  • Plant nutrient uptake and metabolism
  • Plant biochemistry and biosynthesis
  • Circular RNAs in diseases
  • Acupuncture Treatment Research Studies
  • Phytoplasmas and Hemiptera pathogens
  • MicroRNA in disease regulation
  • Photosynthetic Processes and Mechanisms
  • Transgenic Plants and Applications
  • Spectroscopy and Quantum Chemical Studies
  • Plant Pathogenic Bacteria Studies
  • Phytochemicals and Antioxidant Activities
  • Cocoa and Sweet Potato Agronomy
  • Plant Parasitism and Resistance
  • Banana Cultivation and Research
  • Genomics and Phylogenetic Studies
  • Peroxisome Proliferator-Activated Receptors
  • Cancer-related molecular mechanisms research
  • Plant Virus Research Studies
  • Phytochemistry and biological activities of Ficus species
  • Berberine and alkaloids research

Qinghai Meteorological Bureau
2024-2025

Yale University
2025

Shanxi Agricultural University
2021-2024

Shanghai University of Traditional Chinese Medicine
2021-2024

Nankai University
2020-2024

Yueyang Hospital
2021-2024

First Affiliated Hospital of Bengbu Medical College
2024

Fujian Agriculture and Forestry University
2016-2023

Xi'an Polytechnic University
2022-2023

First Hospital of Shijiazhuang
2022-2023

Abstract As one of the widely used additive manufacturing technologies, FDM has been limited by small variety available materials, poor mechanical properties, and lack functionality FDM‐printed parts. In this study, CNT/TPU filaments are prepared, their thermal behavior is determined to lay foundation for process. The effects CNT content on conductivity properties samples investigated, dielectric layers explored capacitive sensing applications. results show that incorporation significantly...

10.1002/admt.202201638 article EN Advanced Materials Technologies 2023-01-29

Recent data have revealed that oxidative products and inflammatory mediators are increased in the insulin‐resistant states of obesity type 2 diabetes mellitus (T2DM). Obese patients with impaired glucose tolerance (IGT) at high risk for developing T2DM incidence dyslipidemia. α‐Lipoic acid (ALA) is a potent antioxidant insulin sensitizing activity. However, it not clear whether ALA effective on lipid parameters humans. This study has investigated 22 obese subjects IGT (obese‐IGT), 13 whom...

10.1038/oby.2011.121 article EN Obesity 2011-05-19

Root samples of 'Sanhu' red tangerine trees infected with and without Candidatus Liberibacter asiaticus (CLas) were collected at 50 days post inoculation subjected to RNA-sequencing isobaric tags for relative absolute quantification (iTRAQ) profile the differentially expressed genes (DEGs) proteins (DEPs), respectively. Quantitative real-time PCR was subsequently used confirm expression 16 selected DEGs. Results showed that a total 3956 78 regulated by HLB-infection. Among most highly...

10.1371/journal.pone.0126973 article EN cc-by PLoS ONE 2015-06-05

Long non-coding RNAs (lncRNAs) play important roles in tumor initiation and progression, including cervical cancer (CC). However, the effects underlying mechanisms of STXBP5-AS1 CC are still unknown. The expression STXBP5-AS1, miR-96-5p, PTEN was explored by qRT-PCR. CCK-8 transwell assays were used to determine on progression. Luciferase report assay RIP explore correction between miR-96-5p CC. In our study, we showed that reduced while upregulated overexpression significantly cells...

10.1016/j.biopha.2019.109082 article EN Biomedicine & Pharmacotherapy 2019-06-15

OBJECTIVE This study aimed to evaluate the efficacy and safety of mulberry twig alkaloids (Sangzhi [SZ-A]) in treatment type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS was a multicenter, randomized, double-blind, double-dummy, parallel controlled noninferiority clinical trial that conducted for 24 weeks. A total 600 patients were randomly allocated SZ-A group (n = 360) or acarbose 240). The primary end point change glycosylated hemoglobin (HbA1c) compared with baseline. In addition,...

10.2337/dc20-2109 article EN Diabetes Care 2021-04-08

Ethylene plays profound roles in plant development. The rate-limiting enzyme of ethylene biosynthesis is 1-aminocyclopropane-1-carboxylate (ACC) synthase (ACS), which generally believed to be a single-activity evolving from aspartate aminotransferases. Here, we demonstrate that, addition catalyzing the conversion S-adenosyl-methionine precursor ACC, genuine ACSs widely have Cβ-S lyase activity. Two N-terminal motifs, including glutamine residue, are essential for conferring ACS activity...

10.1126/sciadv.abg8752 article EN cc-by-nc Science Advances 2021-11-10

Mammalian genomes undergo pervasive transcription in both genic and intergenic regions. Tri-methylation of histone H3 lysine 4 (H3K4me3) is a deeply conserved functionally important modification enriched at transcriptionally active promoters, where it facilitates RNA polymerase activity. H3K4me3 also commonly found regions, its role poorly understood. We interrogated the regulatory elements by using epigenetic editing to efficiently deposit loci. find that instructs activity actively...

10.1101/2025.03.21.644682 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-03-22

Increasing evidence revealed that circular RNAs (circRNAs) play important roles in tumor progression. In the present study, we explored and underlying mechanisms of hsa_circ_0075341 cervical cancer development. Our data showed expression was significantly upregulated associated with larger size, advanced FIGO stage, lymph-node metastasis patients. Hsa_circ_0075341 inhibition reduced cell proliferation invasion vitro. mechanism, negatively regulated miR-149-5p addition, AURKA confirmed as a...

10.1016/j.biopha.2019.109582 article EN Biomedicine & Pharmacotherapy 2019-11-06

Accumulated evidence has revealed the mitigation effects of exogenous melatonin on cold stress in plants. In this study, to investigate defensive roles banana under stress, we researched influences chlorophyll fluorescence parameters, antioxidant defense indexes and expression levels cold-responsive genes cold-stressed ‘Brazil’ seedlings. Results showed that 100 μM achieved best cold-resistance-promoting effect banana. Exogenous treatment significantly increased electron transfer rate, light...

10.3390/horticulturae8030260 article EN cc-by Horticulturae 2022-03-17

Basic helix-loop-helix proteins (bHLHs) play very important roles in the anthocyanin biosynthesis of many plant species. However, reports on blueberry biosynthesis-related bHLHs were limited. In this study, six identified from genome data through homologous protein sequence alignment. Among these bHLHs, VcAN1, VcbHLH42-1, VcbHLH42-2 and VcbHLH42-3 clustered into one group, while VcbHLH1-1 VcbHLH1-2 other group. All bHLH-MYC_N domain, had DNA binding sites reported conserved amino acids bHLH...

10.3390/ijms222413274 article EN International Journal of Molecular Sciences 2021-12-10

Abstract Background Radiation resistance is a major obstacle to the prognosis of cervical cancer (CC) patients. Many studies have confirmed that long non-coding RNAs (lncRNAs) are involved in regulation radiosensitivity cancers. However, whether small nucleolar RNA host gene 12 (SNHG12) regulates CC remains unknown. Methods Quantitative real-time polymerase chain reaction was used measure expression levels SNHG12 and microRNA-148a (miR-148a). The cells evaluated by clonogenic assay. Flow...

10.1186/s12935-020-01654-5 article EN cc-by Cancer Cell International 2020-12-01

Canarium album fruit has great potential to be consumed as a raw material not only for food but also medicine. The diverse active metabolites composition and content of C. fruits greatly affect their pharmacological effects. However, up now, there been no report on the global metabolome differences among from distinct cultivars. In our present study, by using non-targeted metabolomics techniques, we identified 87 DAMs (differentially accumulated metabolites) including 17 types flavonoids...

10.3390/foods11162527 article EN cc-by Foods 2022-08-21

Climate warming can lead to permafrost degradation, potentially resulting in slope failures such as retrogressive thaw slumps (RTSs). The formation of and changes RTSs could exacerbate the degradation environment general. mechanisms RTS progression potential consequences on analogous freeze–thaw cycle are not well understood, owing partly necessitating field work under harsh conditions with high costs. Here, we used multi-source remote sensing surveys quantify an Eboling Mountain Qilian...

10.3390/rs16132490 article EN cc-by Remote Sensing 2024-07-07

Apple canker disease, also named as apple Valsa canker, is one of the most destructive diseases for apples (Malus domestica Borkh.). Cytospora/Valsa spp. are dominant causal agent this but many studies have revealed that fungi from some other genus can cause typical symptoms. In study, we performed fungal pathogen isolation cankered ‘Fuji’ barks. Six representative morphologically different (Strain 1–6) were further subjected to ITS sequencing and evolutionary analysis. Molecular...

10.3390/jof10080536 article EN cc-by Journal of Fungi 2024-07-31

Citrus Huanglongbing (HLB), the most destructive citrus disease, can be transmitted by psyllids and diseased budwoods. Although final symptoms of two main HLB transmission ways were similar hard to distinguish, host responses might different. In this study, global gene changes in leaves ponkan (Citrus reticulata) mandarin trees following psyllid-transmission analyzed at early symptomatic stage (13 weeks post inoculation, wpi) late (26 using digital expression (DGE) profiling. At 13 wpi, 2452...

10.3390/ijms17071063 article EN International Journal of Molecular Sciences 2016-07-02
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