Yingfen Qin
A5034701478- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Risk Factors
- Thyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Birth, Development, and Health
- Nutritional Studies and Diet
- Metabolism, Diabetes, and Cancer
- Thyroid Cancer Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Diabetes Treatment and Management
- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
- Vitamin D Research Studies
- Health, Environment, Cognitive Aging
- Gastroesophageal reflux and treatments
- Sleep and Work-Related Fatigue
- Cancer, Lipids, and Metabolism
- Phytochemistry and biological activities of Ficus species
- Drug Transport and Resistance Mechanisms
- Cardiac Health and Mental Health
- Diet and metabolism studies
- Berberine and alkaloids research
- Sleep and related disorders
First Affiliated Hospital of GuangXi Medical University
2014-2024
Guangxi Medical University
2014-2024
XinHua Hospital
2023-2024
Shanghai Jiao Tong University
2020-2023
Ruijin Hospital
2020
First Affiliated Hospital of Zhengzhou University
2020
National Institutes of Health
2014
Abstract Objective To assess the prevalence of diabetes and its risk factors. Design Population based, cross sectional study. Setting 31 provinces in mainland China with nationally representative data from 2015 to 2017. Participants 75 880 participants aged 18 older—a sample Chinese population. Main outcome measures Prevalence among adults living China, by sex, regions, ethnic groups, estimated 2018 American Diabetes Association (ADA) World Health Organization diagnostic criteria....
Background: Mandatory universal salt iodization (USI) has been implemented in China for 20 years. Although iodine deficiency disorders are effectively controlled, the risk of excess have debated. Methods: A nationally representative cross-sectional study with 78,470 enrolled participants, aged 18 years or older, from all 31 provincial regions mainland was performed. The participants were given a questionnaire and underwent B-mode ultrasonography thyroid. Serum concentrations thyroid...
OBJECTIVE To investigate whether the association between insulin resistance and cardiovascular disease (CVD) differs by glucose tolerance status. RESEARCH DESIGN AND METHODS We analyzed a nationwide sample of 111,576 adults without CVD at baseline, using data from China Cardiometabolic Disease Cancer Cohort Study. Insulin was estimated sex-specific HOMA (HOMA-IR) quartiles for participants with normal tolerance, prediabetes, or diabetes, separately, 1 SD HOMA-IR overall study participants....
OBJECTIVE Uncertainty remains regarding the predictive value of various glycemic measures as they relate to risk diabetes and its complications. Using cutoffs recommended by American Diabetes Association’s 2010 criteria, we determined associations fasting plasma glucose (FPG), 2-h postload (2h-PG), HbA1c with outcomes. RESEARCH DESIGN AND METHODS Baseline medical history, FPG, 2h-PG, were obtained from a population-based cohort 193,846 adults aged ≥40 years in China during 2011–2012. A...
Whether optimal cardiovascular health metrics may counteract the risk of events among patients with prediabetes or diabetes is unclear.
National investigations on age-specific modifiable risk factor profiles for cardiovascular disease (CVD) and mortality are scarce in China, the country that is experiencing a huge cardiometabolic burden exacerbated by population ageing.This nationwide prospective cohort study of 193,846 adults China Cardiometabolic Disease Cancer Cohort Study, 2011-2016. Among 139,925 participants free from CVD at baseline, we examined hazard ratios population-attributable percentages (PAR%s) all-cause...
Abstract Background Whether smoking modifies the associations of diabetes and risk factor management with subsequent cardiovascular disease (CVD), whether related CVD differs among people without are unclear. This study aimed to examine interactions smoking, diabetes, in relation incident CVD. Methods nationwide, population-based, prospective cohort 20 communities from various geographic regions recruited adults aged 40 years or older during 2011–2012. The follow-up survey was conducted...
OBJECTIVE Comprehensive assessment of serum bile acids (BAs) aberrations before diabetes onset remains inconclusive. We examined the association BA profile and coregulation with risk developing type 2 mellitus (T2DM) among normoglycemic Chinese adults. RESEARCH DESIGN AND METHODS tested 23 species in subjects incident (n = 1,707) control matched by propensity score (including age, sex, BMI, fasting glucose) from China Cardiometabolic Disease Cancer Cohort (4C) Study, which was composed...
BackgroundNational investigations of age-specific modifiable risk profiles for diabetes are crucial to promote personalised strategies the prevention and control diabetes, particularly in countries such as China, which is experiencing both a epidemic rapidly ageing population. We aimed examine associations 12 potentially socioeconomic, lifestyle, metabolic factors with nationwide prospective cohort Chinese adults across four age groups.MethodsWe analysed data from China Cardiometabolic...
We aim to investigate the impact of ideal cardiovascular health metrics (ICVHMs) on association between famine exposure and adulthood diabetes risk.This study included 77,925 participants from China Cardiometabolic Disease Cancer Cohort (4C) Study who were born around time Chinese Great Famine free at baseline. They divided into three groups according birth year, including nonexposed (1963-1974), fetal exposed (1959-1962), childhood (1949-1958). Relative risk regression was used examine...
OBJECTIVE This study aimed to evaluate the efficacy and safety of mulberry twig alkaloids (Sangzhi [SZ-A]) in treatment type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS was a multicenter, randomized, double-blind, double-dummy, parallel controlled noninferiority clinical trial that conducted for 24 weeks. A total 600 patients were randomly allocated SZ-A group (n = 360) or acarbose 240). The primary end point change glycosylated hemoglobin (HbA1c) compared with baseline. In addition,...
Background Education attainment can improve life expectancy and guide healthy behaviours throughout an entire lifetime. A nationwide longitudinal study of the association education status with risk hypertension its control in China is lacking. Methods The Cardiometabolic Disease Cancer Cohort Study a multicentre, population-based, prospective cohort study. We performed baseline survey from 2011 to 2012. follow-up visit was conducted during 2014–2016. 101 959 subjects were included final data...
Background Previous studies reported that early‐life exposure to undernutrition is associated with the risk of diabetes mellitus and metabolic syndrome in adulthood, but association cardiovascular disease ( CVD ) later life remains unclear. The current study aimed investigate whether Chinese famine early . Methods Results We used data from REACTION (Risk Evaluation Cancers Diabetic Individuals: A Longitudinal Study), which recruited a total 259 657 community‐dwelling adults aged 40 years or...
OBJECTIVE We aimed to determine the individual and combined associations of lifestyle metabolic factors with new-onset diabetes major cardiovascular events among a Chinese population aged ≥40 years. RESEARCH DESIGN AND METHODS Baseline information, waist circumference, blood pressure, lipid profiles, glycemic status were obtained in nationwide, multicenter, prospective study 170,240 participants. During up 5 years follow-up, we detected 7,847 individuals according American Diabetes...
Background: Iodine is important in both thyroid function and human metabolism. Studies have explored the effect of iodine on metabolic disorders through function. This study aimed to investigate relationship between status disorders, such as syndrome (MetS), hypertension, impaired glucose metabolism, central obesity, dyslipidemia. Methods: A total 51,795 subjects aged ≥18 years from TIDE (Thyroid Disorders, Status Diabetes, a national epidemiological cross-sectional study) program were...
Background Universal salt iodization (USI) was implemented in mainland China 1996. The prevalence of hyperthyroidism and its risk factors now require examination. Methods Data were acquired from a nationwide Thyroid, Iodine, Diabetes Epidemiological survey (TIDE 2015–2017) 78,470 subjects 31 provinces. Iodine status, thyroid hormones antibodies measured. Results After two decades USI, the overt (OH), Graves’ disease (GD), severe subclinical (severe SCH), mild (mild SCH) 0.78%, 0.53%, 0.22%,...
The updated definition of hypertension by the American College Cardiology (ACC) and Heart Association (AHA) is an important paradigm shift has lead to extensive discussion. We aimed examine association between blood pressure (BP) categories risk cardiovascular diseases (CVDs) with potential modifications from other health metrics (CVHMs).This prospective study included 91,204 participants ≥40 years recruited 20 community sites across mainland China. Participants were followed up during...
Background: Iodine intake is associated with thyroid autoimmunity. In this study, we evaluated the changes in autoimmunity after 20 years of universal salt iodization (USI) China. Methods: A total 78,470 subjects (18 or older) from 31 provincial regions mainland China participated study. Serum peroxidase antibody (TPOAb), thyroglobulin (TgAb), TSH receptor antibody, thyrotropin (TSH), and urinary iodine concentration (UIC) were measured. Results: Positive TPOAb TgAb detected 10.19% [CI...