Zhen Ye

ORCID: 0000-0001-8842-1157
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Infectious Diseases and Tuberculosis
  • MRI in cancer diagnosis
  • Reproductive Biology and Fertility
  • Rheumatoid Arthritis Research and Therapies
  • Hematological disorders and diagnostics
  • Musculoskeletal synovial abnormalities and treatments
  • Gastrointestinal disorders and treatments
  • Spine and Intervertebral Disc Pathology
  • Diet, Metabolism, and Disease
  • Prenatal Screening and Diagnostics
  • Tendon Structure and Treatment
  • Spondyloarthritis Studies and Treatments
  • Bone and Joint Diseases
  • Diagnosis and treatment of tuberculosis
  • Congenital Anomalies and Fetal Surgery
  • Spinal Fractures and Fixation Techniques
  • Cardiac Imaging and Diagnostics
  • Surgical site infection prevention
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Coronary Interventions and Diagnostics
  • Radiomics and Machine Learning in Medical Imaging
  • Metabolism, Diabetes, and Cancer
  • Ectopic Pregnancy Diagnosis and Management
  • Maternal and fetal healthcare

Jiangxi University of Traditional Chinese Medicine
2024

Guangxi Medical University
2021-2022

First Affiliated Hospital of GuangXi Medical University
2021-2022

Zhejiang Center for Disease Control and Prevention
2019-2022

First Affiliated Hospital of Fujian Medical University
2008-2021

Shanghai Electric (China)
2021

Fujian Medical University
2008-2021

Institute of Microbiology
2020

Chinese Academy of Sciences
2020

Cornell University
1998-2019

Ankylosing spondylitis (AS) is a chronic progressive inflammatory disease of the spine and its affiliated tissues. AS mainly affects axial bone, sacroiliac joint, hip spinal facet, adjacent ligaments. We used machine learning (ML) methods to construct diagnostic models based on blood routine examination, liver function test, kidney test patients with AS. This method will help clinicians enhance efficiency allow receive systematic treatment as soon possible.We consecutively screened 348...

10.1007/s40744-022-00481-6 article EN cc-by-nc Rheumatology and Therapy 2022-08-06

Originating as supplementary firms that operate in and around YouTube’s advertising infrastructure, Multichannel Networks (MCNs) have become a renewed form of cultural intermediaries shaping platform-based production (Lobato 2016; Craig Cunningham 2019). The emergence MCNs represents “an opportunity to revisit some elements the theory base update it for platform economy” 2016, 350). To hold with this appeal, research investigates MCNs’ operations context China’s e-commerce livestreaming...

10.5210/spir.v2024i0.14078 article EN AoIR Selected Papers of Internet Research 2025-01-02

The study was aimed to determine the association of platelet-lymphocyte ratio (PLR) with disease activity ankylosing spondylitis (AS). A total 275 patients, including 180 AS patients and 95 non-AS participated in study. We assessed a full blood count for each participant. Platelet monocyte (PMR), monocytes lymphocyte (MLR), neutrophil (MNR), platelet (PLR), (NLR), (PNR) were calculated. LASSO logistic regression analyses performed establish nomogram. Receiver operating characteristic (ROC)...

10.3389/fimmu.2021.760214 article EN cc-by Frontiers in Immunology 2021-11-05

Purpose. The purpose was to explore the relationship between monocyte-to-lymphocyte ratio (MLR) and severity of spinal tuberculosis. Methods. A total 1,000 clinical cases were collected, including 496 tuberculosis 504 nonspinal Laboratory blood results C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white cells (WBC), hemoglobin (HGB), platelets (PLT), neutrophil count, percentage neutrophils, lymphocyte lymphocytes, monocyte monocytes, MLR, -to- (PMR), (PLR), (NLR), (PNR)....

10.1155/2022/7340330 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-05-20

10.1016/j.ejogrb.2020.01.036 article EN European Journal of Obstetrics & Gynecology and Reproductive Biology 2020-01-27

The present study attempted to predict blood transfusion risk in spinal tuberculosis surgery by using a novel predictive nomogram.The was conducted on the clinical data of 495 patients (167 group and 328 non-transfusion group) who underwent our hospital from June 2012 2021. least absolute shrinkage selection operator (LASSO) multivariable logistic regression analyses were used screen out statistically significant parameters, which included establish nomogram model. receiver operating...

10.1186/s12891-022-05132-z article EN cc-by BMC Musculoskeletal Disorders 2022-02-25

Objective This study aimed to examine the associations between contrast-enhanced ultrasound (CEUS) imaging and synovial hypervascularity synovitis score in a rabbit model of antigen-induced arthritis (AIA), compared with power Doppler (PDUS). Methods We investigated 50 knee joints 25 AIA rabbits (AIA group), 10 five sham-injected (control group). PDUS CEUS images were evaluated at 8 th week. Ultrasound-guided biopsies targeted area hypervascularity, microvessel density (MVD) was by...

10.1177/0300060519874159 article EN cc-by-nc Journal of International Medical Research 2019-09-23

Lack of physical activity and excessive sitting time contributed to ectopic fat accumulation, especially in the liver. Previous studies have illustrated harm sedentary behaviour benefits on fatty liver disease. We aimed explore association between patterns risk metabolic dysfunction-associated disease (MAFLD) using isotemporal substitution model examine effect replacing one another while keeping total other behaviours fixed among Chinese middle-aged elderly population.This study included 161...

10.1111/liv.15439 article EN Liver International 2022-09-27

Objective: The study aimed to develop and validate a nomogram model with clinical risk factors radiomic features for differentiating tuberculous spondylitis (TS) from pyogenic (PS). Methods: A total of 254 patients TS (n = 141) or PS 113) were randomly divided into training 180) validation 74) groups. In addition, 43 (TS 22 21) collected construct test cohort. t -test analysis, de-redundancy minimum absolute shrinkage selection operator (lasso) algorithm utilized on the set obtain optimal...

10.2147/idr.s388868 article EN cc-by-nc Infection and Drug Resistance 2022-12-01

Thoracic ossification of the ligamentum flavum (OLF) is a major cause thoracic myelopathy, which often accompanied by multiple segmental stenosis or other degenerative spinal diseases. However, in above situations, it difficult to determine exact segment responsible. The objective this study was analyze three-dimensional (3D) radiological parameters order establish novel diagnostic method for discriminating responsible OLF-induced and evaluate its superiority compared conventional...

10.21037/qims-20-713 article EN Quantitative Imaging in Medicine and Surgery 2021-03-10

Post-translational modification plays a critical role in viral replication. Previously we reported that neddylation of PB2 influenza A virus (IAV) can inhibit However, found NEDD8 overexpression still the replication K699R mutant viruses, implying other protein(s) be neddylated. In this study, revealed M1 IAV also modified by NEDD8. We E3 ligase HDM2 significantly promotes neddylation. Furthermore, identified K187 as major site. generated an K187R (WSN-M1 K187R) and compared growth wild-type...

10.1099/jgv.0.001503 article EN Journal of General Virology 2020-10-05

Objective This study is aimed to develop a new nomogram for the clinical diagnosis of osteoarticular tuberculosis (TB). Methods xCell score estimation obtained immune cell type abundance scores. We downloaded expression profile GSE83456 from GEO and proceed estimation. The routine blood examinations 326 patients were collected further validation. analyzed univariate multivariate logistic regression identified independent predicted factor developing nomogram. performance was assessed using...

10.1371/journal.pone.0252875 article EN cc-by PLoS ONE 2021-06-15

Background: The purpose of this study was to predict the surgical site infection risk after spinal tuberculosis surgery based on a nomogram. Patients and Methods: We collected clinical data patients who underwent in our hospital included all least absolute shrinkage selection operator (LASSO) regression analysis. Next, selected parameters were analyzed using logistic regression. analysis receiver operating characteristic (ROC) curve further used obtain statistically significant parameters....

10.1089/sur.2022.042 article EN cc-by-nc Surgical Infections 2022-06-20

Progress in developing novel rational treatments for rheumatoid arthritis (RA) critically depends on preclinical work experimental animals. However, there is lack of insight into the most appropriate mode noninvasive measurement disease status RA. This study compared sonography with serum biomarkers a rabbit model RA.Six-month-old male New Zealand White rabbits were randomized 2 groups: antigen-induced group (n = 25), which was subjected to ovalbumin immunization and intra-articular...

10.7863/ultra.15.10044 article EN Journal of Ultrasound in Medicine 2016-08-30

The current study is aimed at developing and validating a nomogram of the risk failure internal fixation devices in Chinese patients undergoing spinal fixation. We collected data from total 1139 admitted for surgery First Affiliated Hospital Guangxi Medical University May 2012 to February 2019. Of these, 1050 were included group 89 device group. Patients divided into training validation tests. assessment used 14 characteristics. In test, feature selection model was optimized using least...

10.1155/2021/8840107 article EN cc-by BioMed Research International 2021-01-01

Abstract Purpose. To describe the sonographic (US) appearance of fetal anal canal and rectum establish nomograms their normal measurements. Methods. This was a prospective, cross‐sectional study 524 healthy women (mean age, 27 years; range, 21–37 years) with singleton pregnancy between 18 40 weeks gestational age (GA). High‐resolution transabdominal US used to visualize measure rectum. Results. Satisfactory images measurements were obtained in 496 fetuses. The diameters plotted as function...

10.1002/jcu.20810 article EN Journal of Clinical Ultrasound 2011-03-29

To investigate the clinical value of acoustic radiation force impulse (ARFI) elastography in differential diagnosis focal liver lesions.ARFI was performed for 169 lesions from 163 patients with and 15 healthy volunteers, virtual touch tissue imaging (VTI) findings measured shear wave velocity (SWV) were obtained compared between groups. The t-test applied comparison means two groups; one-way analysis variance multiple groups, Student-Newman-Keuls test further any groups.Benign stiffer or...

10.3760/cma.j.issn.1007-3418.2016.02.010 article EN PubMed 2016-02-01

There have been no studies with large sample sizes on growth of the pedicle C2 in children. In present study we measured through computed tomography (CT) imaging children aged less than 14 years and evaluated suitability 3.5-mm screw for such The was conducted CT morphometric images 420 our hospital between June 2018 2020. width (D1), length (D2), height (D3), inclination angle (α), tail (β) were measured. One-way analysis variance Student's t test used statistical analyses. least-square...

10.1002/ca.23837 article EN Clinical Anatomy 2022-01-28

Acoustic radiation force impulse (ARFI) elastography, the aspartate aminotransferase-to-alanine aminotransferase ratio (AAR), aminotransferase-to-platelet index (APRI), and fibrosis-4 (FIB-4) are widely used to assess liver fibrosis. However, efficacies of these methods in evaluation hepatic functional reserve remain unclear. In this study, we investigated relationship between ARFI elastography combined with either AAR, APRI, or FIB-4 Child-Pugh (CP) class for patients chronic hepatitis B...

10.6061/clinics/2020/e1670 article EN cc-by Clinics 2020-01-01

There have been few literature reports on the use of perioperative parameters to predict risk albumin transfusion after spinal tuberculosis surgery based application nomogram and propensity score matching (PSM) analysis.The purpose was a combination PSM nomogram.The clinical data patients were collected in our hospital, including preoperative data, laboratory tests, postoperative data. All divided into 2 groups, group non-albumin group. The analysis used adjust baseline groups. further...

10.1016/j.wneu.2021.10.102 article EN cc-by-nc-nd World Neurosurgery 2021-10-19
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