Joed Pires de Lima Júnior

ORCID: 0000-0001-6886-281X
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About
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Research Areas
  • Toxoplasma gondii Research Studies
  • Parasitic Infections and Diagnostics
  • Natural Antidiabetic Agents Studies
  • Advanced Glycation End Products research
  • Ginkgo biloba and Cashew Applications
  • Cytomegalovirus and herpesvirus research
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Oral and Craniofacial Lesions
  • Dental Health and Care Utilization
  • Synthesis and bioactivity of alkaloids
  • Synthesis and Biological Evaluation
  • Galectins and Cancer Biology
  • Natural product bioactivities and synthesis
  • Cardiovascular Issues in Pregnancy
  • Dental Trauma and Treatments
  • Phytochemicals and Antioxidant Activities

Universidade Federal de Uberlândia
2020-2025

Centrus Diagnósticos por Imagem
2021

Communications & Power Industries (United States)
2021

Abstract Studies based on medicinal plants have stood out as a complementary treatment intervention to type 2 Diabetes mellitus and its complications. Among the Brazilian plants, we highlight Cordiera sessilis (Vell.) Kuntze, in turn, has been studied several chemical biological studies due ethnopharmacological indications. Thus, this study aimed evaluate antimicrobial, antioxidant, antiglycation, digestive enzyme inhibition effects of fractions obtained from ethanolic extract stem bark C....

10.1590/0001-3765202520241067 article EN cc-by Anais da Academia Brasileira de Ciências 2025-01-01

The conventional treatment of congenital toxoplasmosis is mainly based on the combination sulfadiazine and pyrimethamine. However, therapy with these drugs associated severe side effects resistance, requiring study new therapeutic strategies. There are currently many studies natural products, including Copaifera oleoresin, showing actions against some pathogens, as Trypanosoma cruzi Leishmania . In present study, we investigated leaf hydroalcoholic extract oleoresin from multijuga Toxoplasma...

10.3389/fcimb.2023.1113896 article EN cc-by Frontiers in Cellular and Infection Microbiology 2023-02-13

Toxoplasma gondii is the etiologic agent of toxoplasmosis, a disease that affects about one-third human population. Most infected individuals are asymptomatic, but severe cases can occur such as in congenital transmission, which be aggravated with other pathogens, HIV-positive pregnant women. However, it unknown whether infection by Trypanosoma cruzi, Chagas disease, well one its proteins, P21, could aggravate T. infection.In this sense, we aimed to investigate impact cruzi and recombinant...

10.3389/fimmu.2023.1243480 article EN cc-by Frontiers in Immunology 2023-10-16

Galectin-3 (Gal-3) is a β-galactoside-binding lectin expressed in cells of the placental microenvironment. This involved various biological processes, such as modulation immune system and control parasitic illness. Toxoplasma gondii infection can lead to congenital transmission cause miscarriages, prematurity fetal anomalies. However, little known about role Gal-3 T. study aimed unravel underlying mechanisms during infection. For this purpose, we promoted knockdown expression by using RNA...

10.3389/fcimb.2024.1459810 article EN cc-by Frontiers in Cellular and Infection Microbiology 2024-11-25

A Cárie na Primeira Infância (CPI), doença oportunista de natureza aguda, progressão rápida e etiologia multifatorial. É um problema saúde pública que pode provocar severas consequências se não diagnosticada tratada precocemente. CPI está associada às condições socioeconômicas, culturais sociais dos indivíduos. Diante disso, este artigo objetiva relatar dois casos clínicos pacientes do sexo masculino, três anos idade com bom comportamento frente ao tratamento odontológico outro cinco...

10.36065/robrac.v30i89.1436 article PT Revista Odontológica do Brasil Central 2021-07-02
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