Yang Chen

ORCID: 0000-0001-7117-7557
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Reproductive Physiology in Livestock
  • RNA modifications and cancer
  • Genetic and phenotypic traits in livestock
  • Chromosomal and Genetic Variations
  • Genetic Mapping and Diversity in Plants and Animals
  • Salmonella and Campylobacter epidemiology
  • RNA Research and Splicing
  • Plant Reproductive Biology
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Genomics and Phylogenetic Studies
  • Animal Genetics and Reproduction
  • Sirtuins and Resveratrol in Medicine
  • Biochemical Analysis and Sensing Techniques
  • Virology and Viral Diseases
  • Wetland Management and Conservation
  • Animal Nutrition and Physiology
  • Microbial infections and disease research
  • Reproductive System and Pregnancy
  • Ecology and Conservation Studies
  • Skin Protection and Aging
  • Microbial Metabolism and Applications
  • melanin and skin pigmentation
  • Cytokine Signaling Pathways and Interactions

Anhui Agricultural University
2017-2024

Sichuan Agricultural University
2023

Zhongkai University of Agriculture and Engineering
2021-2023

Wuhan Botanical Garden
2023

Zhejiang University
2021-2023

Chinese Academy of Sciences
2023

Key Laboratory of Guangdong Province
2021-2023

Yangzhou University
2013-2021

South China Agricultural University
2020

Shantou University
2019

Resveratrol, a natural antioxidant, anti-inflammatory plant extract, was found to have protective effect in poultry subjected heat stress. In this study, we strove characterize resveratrol on intestinal of duck exposed acute stress and investigate the underlying mechanism. A total 120 Shan-ma ducks (60 days old) were randomly divided into 2 groups. The control group fed basal diet, diet supplemented with 400 mg/kg resveratrol. Animals groups kept at temperature 24°C ± 2°C for 15 d. Then,...

10.1016/j.psj.2021.101459 article EN cc-by-nc-nd Poultry Science 2021-09-02

Nocardia cyriacigeorgica, an opportunistic pathogen, is increasingly implicated in human infections. This pathogen predominantly causes pulmonary infections, leading to acute, subacute, or chronic necrotizing suppurative lesions, severe cases, may progress disseminated Effective clinical diagnosis, prevention, and treatment strategies require a thorough understanding of its biological characteristics pathogenic mechanisms. However, despite the rising incidence nocardial diseases, research on...

10.1186/s12941-025-00791-x article EN cc-by-nc-nd Annals of Clinical Microbiology and Antimicrobials 2025-04-05

Long noncoding RNAs (lncRNAs) are involved in regulating animal development, however, their function the onset of puberty goats remain largely unexplored. To identify genes controlling regulation goats, we measured lncRNA and mRNA expression levels from hypothalamus. We applied RNA sequencing analysis to examine hypothalamus pubertal (case; n = 3) prepubertal (control; goats. Our results showed 2943 predicted lncRNAs, including 2012 differentially expressed which corresponded 5412 target...

10.1186/s12864-017-3578-9 article EN cc-by BMC Genomics 2017-02-14

Infectious bronchitis is a severe disease caused by infectious virus (IBV) that affects fowl flocks worldwide. The understanding of the mechanisms involved in IBV evolution and variation would provide important theoretical basis for prevention control future.IBV strain GD was isolated from southern China 2013 complete genome sequencing phylogenetic analysis were performed.The approximately 27,680 nt comprised six genes, with insertions mutations most structural genes. S1 gene showed highest...

10.1186/s12985-016-0497-3 article EN cc-by Virology Journal 2016-03-08

Summary Humans have domesticated diverse species from across the plant kingdom; however, our current understanding of domestication is largely founded on major cereal crops. Here, we examine evolutionary processes and genetic basis underlying water caltrop ( Trapa spp., Lythraceae), a traditional, yet presently underutilized non‐cereal crop that sustained early Chinese agriculturalists. We generated chromosome‐level genome assembly tetraploid T. natans , then divided allotetraploid into two...

10.1111/pbi.13758 article EN Plant Biotechnology Journal 2021-12-03

Selecting suitable feed types and understanding the gastrointestinal digestive mechanism are helpful for growth health of calves in intensive dairy farming. However, effects on rumen development changing molecular genetic basis regulatory by using different still unclear. Nine 7-day-old Holstein bull were randomly divided into GF (concentrate), GFF (alfalfa: oat grass = 3:2) TMR (concentrate: alfalfa grass: water 0.30:0.12:0.08:0.50) diet experiment groups. Rumen tissue serum samples...

10.3390/genes14051093 article EN Genes 2023-05-16

Esophageal squamous cell carcinoma is a leading cause of cancer death. Mapping the transcriptional landscapes such as isoforms, fusion transcripts, well long noncoding RNAs have played central role to understand regulating mechanism during malignant processes. However, canonical methods short-read RNA-seq are difficult define entire polyadenylated RNA molecules. Here, we combined single-molecule real-time sequencing with generate high-quality reads and survey program in esophageal cells....

10.3389/fgene.2019.00915 article EN cc-by Frontiers in Genetics 2019-10-04

Abstract Granulosa cells (GCs) play an important role in the development of follicles. In this study, we investigate impact heat stress at 41°C and 43°C on duck GCs' proliferation steroids secretion. And, transcriptomic responses to treatment were examined using RNA‐sequencing analysis. Digital gene expression profiling was used screen identify differentially expressed genes (fold change ≥ 2 Q value < 0.05). Further, differential (DEGs) classified into GO categories KEGG pathways. The...

10.1111/asj.13617 article EN Animal Science Journal 2021-01-01

Autotetraploid rice is a useful germplasm for polyploid breeding; however, low seed setting major hindrance its utilization. Here, we reported the development of new tetraploid rice, Huoduo1 (H1), which has characteristic high fertility, from crossing generations autotetraploid rice. Cytological observations displayed fertility pollen (95.62%) in H1, lower percentage mother cell (PMC) abnormalities, and stable chromosome configurations during process compared with parents. Using RNA-seq...

10.3390/ijms21197046 article EN International Journal of Molecular Sciences 2020-09-24

The mechanisms by which GnIH regulates the steroid synthesis pathway in duck granulosa cells remain poorly understood. In this study, we measured hormone secretion ELISA and reproduction-associated gene expression quantitative real-time Polymerase Chain Reaction (qPCR) treated with different concentrations of (0, 0.1, 1, 10, 100 ng/mL) for 24 h. genome-wide profiles GnIH-treated (0 10 were evaluated high-throughput RNA sequencing. Compared untreated cells, hormones E2, E1, P4, T was...

10.1590/1984-3143-ar2021-0036 article EN cc-by Animal Reproduction 2021-01-01

Puberty is the period during a female mammal's life when it enters estrus and ovulates for first time; this indicates that mammal capable of reproduction. The onset puberty complex tightly coordinated biological event; has been reported microRNAs (miRNAs) are involved in regulating initiation puberty. We performed miRNA sequencing on pituitary tissue from prepubescent pubescent goats to investigate differences expression goats. target genes these miRNAs were evaluated by GO enrichment KEGG...

10.1186/s12958-018-0370-x article EN cc-by Reproductive Biology and Endocrinology 2018-05-25

Epigenetics plays an important role in controlling female puberty. Both DNA methylation and long non-coding RNAs (lncRNA) regulate the initiation of puberty by affecting expression genes related to While recent studies have indicated that lncRNA represses lncRNA, its regulating remains unclear. To explore mechanism between lncRNAs during onset, we performed whole-genome bisulphite sequencing (WGBS) RNA-sequencing (RNA-seq). We found was inversely correlated gene levels Methylation gradually...

10.1111/rda.13246 article EN Reproduction in Domestic Animals 2018-07-07

Abstract Salmonella Enteritidis (SE) can be transmitted to eggs through cecum or the ovary from infected layers and causes food poisoning in humans. The mechanism of cecal transmission has been extensively studied. However, route transovarian SE remain unclear. In this study, ducks were orally inoculated with SE, ovarian follicles stroma collected detect infection. immune responses triggered innate adaptive genes (TLR4, NOD1, AvβD7, IL‐1β) upregulated significantly during challenge....

10.1002/jcp.27790 article EN Journal of Cellular Physiology 2018-11-27

Abstract Lipopolysaccharide (LPS) reduces the reproductive performance of laying ducks, especially during hot summer months. To study underlying mechanisms, we investigated effects different LPS concentrations and heat on duck granulosa cell (GC) proliferation steroid biosynthesis in vitro. We GC proliferation, secretion, activation MAPK pathway. The cycle results showed that treatment alone did not significantly affect whereas mRNA expression levels IGF2 , IGFBP2 CyclinD1 were downregulated...

10.1111/asj.13851 article EN Animal Science Journal 2023-01-01

A surface-flow wetland and a subsurface-flow respectively were constructed at the entrance of Dian Lake in Yunnan Province. Six plants such as Canna indica L., Scirpus tabernaemontanl Gmel., Eichornia crassipes (Mart.) Solms., Oenanthe ja vania (Bl.) DC., Acorus calamus Phragmitas communis Trin. planted two wetlands separated sections on condition that hydraulic loading was 12 cm/d, retention time (HRT) 3 d. The results show removal efficiencies subsurface TP TN with canna L. or Geml. are...

10.4028/www.scientific.net/amr.610-613.1409 article EN Advanced materials research 2012-12-01
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