Zsófi Sajtos

ORCID: 0000-0001-7239-2304
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About
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Research Areas
  • Bee Products Chemical Analysis
  • Insect and Pesticide Research
  • Antifungal resistance and susceptibility
  • Heavy metals in environment
  • Isotope Analysis in Ecology
  • Plant and animal studies
  • Water Quality and Pollution Assessment
  • Heavy Metals in Plants
  • Bacterial biofilms and quorum sensing
  • Cystic Fibrosis Research Advances
  • Parasitic Diseases Research and Treatment
  • Legionella and Acanthamoeba research
  • Environmental Toxicology and Ecotoxicology
  • Geochemistry and Geologic Mapping
  • Phytochemicals and Antioxidant Activities
  • Mercury impact and mitigation studies
  • Bone Tissue Engineering Materials
  • Radioactivity and Radon Measurements
  • Nanoparticles: synthesis and applications
  • Freshwater macroinvertebrate diversity and ecology
  • Plant Micronutrient Interactions and Effects
  • Soil and Environmental Studies
  • Landfill Environmental Impact Studies
  • Aerogels and thermal insulation
  • Knowledge Management and Technology

University of Debrecen
2019-2025

Given the risk of Candida albicans overgrowth in gut, novel complementary therapies should be developed to reduce fungal dominancy. This study highlights antifungal characteristics a Bacillus subtilis-derived secondary metabolite, surfactin with high potential against C. albicans. Surfactin inhibited growth following 1-hour exposure, addition reduced adhesion and morphogenesis. Specifically, did not affect level reactive oxygen species but increased glutathione. Surprisingly, ethanol...

10.1016/j.biopha.2022.113220 article EN Biomedicine & Pharmacotherapy 2022-06-04

Electrospinning has recently been recognized as a potential method for use in biomedical applications such nanofiber-based drug delivery or tissue engineering scaffolds. The present study aimed to demonstrate the electrospinning preparation and suitability of β-tricalcium phosphate-modified aerogel containing polyvinyl alcohol/chitosan fibrous meshes (BTCP-AE-FMs) bone regeneration under vitro vivo conditions. mesh physicochemical properties included 147 ± 50 nm structure, aqueous media...

10.3390/ijms24087562 article EN International Journal of Molecular Sciences 2023-04-20

Abstract The assessment of heavy metal pollution in leaves and soils is essential environmental health monitoring. We assessed the effect anthropogenic activities along an industrial–urban–rural gradient roadside soil tree Bangladesh based on their concentration. concentrations Pb, Cr, Ni, Cd were analysed Ficus benghalensis , Swietenia macrophylla Polyalthia longifolia topsoil samples using ICP-OES. used indices to quantify impact contaminants ecosystems. Our findings indicated that there...

10.1038/s41598-025-91683-9 article EN cc-by Scientific Reports 2025-02-26

Increasing pollution of aquatic ecosystems due to anthropogenic activities underscores the urgent need for effective water quality monitoring. This study evaluates use fish scales from chub (Squalius cephalus) and nase (Chondrostoma nasus) as non-invasive bioindicators trace macroelement in Maros/Mureș River. We conducted qualitative quantitative elemental analyses using X-ray fluorescence (XRF) inductively coupled plasma optical emission spectrometry (ICP-OES). Scanning electron microscopy...

10.3390/biology14040344 article EN cc-by Biology 2025-03-26

Fish scales absorb different elements into the calcified matrix from surrounding waters as well foods consumed. Scales microchemistry is drawing rising attention for its applicability in a wide range of fields, including environmental and ecological studies. The article represents an elemental analysis five commercially important coastal fishes: Tenualosa ilisha, Sillaginopsis panijus, Lates calcarifer, Otolithoides pama, Rhinomugil corsula . concentrations essential trace were measured...

10.3389/fmars.2025.1546313 article EN cc-by Frontiers in Marine Science 2025-04-01

Abstract Metal contamination poses a high risk for organisms, especially those with extensive food chain relevancy. Thus, elevated concentration of metals is considered major cause concern in crops. This study aimed to evaluate the short-term responses sorghum and Sudan grass different Cd/Zn doses complex germination test by assessing growth parameters, tissue metal concentrations, interaction accountant ecophysiological elemental alterations. To do so, radicle hypocotyl length were...

10.1007/s10653-025-02485-x article EN cc-by Environmental Geochemistry and Health 2025-04-21

Candida auris is a dangerous fungal pathogen that causes outbreaks in health care facilities, with infections associated high mortality rate. As conventional antifungal drugs have limited effects against the majority of clinical isolates, new and innovative therapies are urgently needed.

10.1128/msphere.00710-21 article EN mSphere 2021-10-13

Several studies show that the elemental content of honey entirely depends on botanical and geographical origin, but information is incomplete regarding its time-dependent composition changes. Twenty-six acacia three samples with unknown origin were collected between 1958 2018 analysed for by Microwave Plasma Atomic Emission Spectrometry (MP-AES). The analysis was coupled independent dating method Accelerator Mass (AMS) to confirm calendar age test possibility radiocarbon based bee products,...

10.1016/j.scitotenv.2020.139686 article EN cc-by-nc-nd The Science of The Total Environment 2020-05-25

The biggest threat to beekeeping is varroosis caused by the mite Varroa destructor. Chemicals available treat this fatal disease may present problems of resistance or inconsistent efficacy. Recently, lithium chloride has appeared as a potential alternative. To date, amount residue treatments leave in honeybee products poorly understood. Honeybees were fed with 25 mM lithiated sugar syrup, which was used earlier studies. accumulation and elimination monitored bees their for 22 days. Lithium...

10.3390/insects12070579 article EN cc-by Insects 2021-06-25

Septic tanks without proper construction and insulation entail a significant risk to the environment. In this study, environmental impacts of permeably designed septic tank on shallow groundwater contamination are investigated, changes in water quality period after its elimination 2014 assessed. For purpose evaluating pollution level site, 10 monitoring wells were installed around 2012 long-term was carried out. Analytical measurements revealed operational tank. Extremely high concentrations...

10.3390/w15050884 article EN Water 2023-02-24

Disposal sites without adequate engineering controls pose a significant risk to the environment. In present study, environmental hazards of an abandoned and unrecultivated liquid waste disposal are investigated with special focus on soil shallow groundwater contamination. After period operation from 1994 2010, when wastewater collection municipality was regulated, site subsequently decommissioned further action. Eight monitoring wells have been established in basins surrounding area...

10.3390/w14020226 article EN Water 2022-01-13

In this study, growth and ionomic responses of three duckweed species were analyzed, namely Lemna minor, Landoltia punctata, Spirodela polyrhiza, exposed for short-term periods to hexavalent chromium or nickel under laboratory conditions. It was found that different had distinct patterns can change considerably due metal treatments. The results also show that, because the stress-induced increase in leaf mass-to-area ratio, studied showed order uptake efficiency if plant area used as unit...

10.3390/plants12010180 article EN cc-by Plants 2023-01-01

The applicability of capillary electrophoresis (CE) with light-emitting diode-induced fluorescence detection (LEDIF) for the separation sugars in honey samples was studied. An amount 25 mM ammonium acetate (pH 4.5) 0.3% polyethylene oxide (PEO) found to be optimal efficient carbohydrates. 8-aminopyrene-1,3,6-trisulfonic acid (APTS) used labeling carbohydrate standards and detection. optimized method applied quantitative analysis fructose glucose by direct injection samples. Apart from...

10.3390/separations10030150 article EN cc-by Separations 2023-02-23

In this research, contamination levels and the spatial pattern identification, as well human environmental health risk assessments of heavy metals in phreatic groundwater aquifer Oued Souf Valley were investigated for first time. The applied methodology comprised a combination heavy-metal pollution indices, inverse distance weighting, assessment through water ingestion on samples collected from (14) monitoring wells. trend showed Al > B Sr Mn Fe Pb Ni Cr Ba Cu Zn. Similarly, enrichment...

10.3390/hydrology10100201 article EN cc-by Hydrology 2023-10-15

Soil contamination caused by the presence of Cd and excess amount Zn is a widespread concern in agricultural areas, posing significant risks to growth development crops. In this paper, early-stage metal (Cd Zn) accumulation potential rapeseed (Brassica napus L.) grown under different application schemes were assessed determining radicle hypocotyl length micro- macro elemental composition plantlets after 24, 72, 120 h. The results indicated that single co-application significantly reduced...

10.1016/j.chemosphere.2024.141235 article EN cc-by Chemosphere 2024-01-16

Abstract In present study the effect of iron (Fe) and manganese (Mn) contamination was assessed by modeling a freshwater food web water, zooplankton ( Daphnia pulex ), zebrafish Danio rerio ) under laboratory conditions. Metals were added to rearing media D. , enriched fed in feeding trial. The elemental analysis zooplankton, fish revealed significant difference treatments compared control. Mn level increased almost parallel with dose supplementation, as well Fe differed statistically. A...

10.1007/s12011-020-02190-z article EN cc-by Biological Trace Element Research 2020-05-23

β-Tricalcium phosphate was combined with silica aerogel in composites prepared using the sol-gel technique and supercritical drying. The materials were used this study to check their biological activity bone regeneration potential MG63 cell experiments. sintered 100 °C steps range of 500-1000 °C. Their mechanical properties, porosities, solubility determined as a function sintering temperature. Dissolution studies revealed that released Ca-/P molar ratios appeared be optimal support tissue...

10.3390/biomedicines10030662 article EN cc-by Biomedicines 2022-03-12

Cladocerans are biological indicators of environmental changes. Their remains provide information on past changes in lake environments. We studied the correspondence between contemporary Cladocera assemblages and their subfossil from an oxbow lake. sought to demonstrate that there were differences among various sites with different utilization based physical–chemical variables. The lake’s two sides used as fishing sites, where angling is main activity. middle site under nature protection...

10.3390/w14142149 article EN Water 2022-07-06

In this paper, we present the time-dependent elemental composition and AMS radiocarbon dating results of 36 rape, sunflower forest honey samples, collected between 1985 2018 in geographically close locations. Based on information, conclude that bee products regardless type provide useful environmental information previous decades, such as decreasing trend airborne Pb emission can be traced. However, agree less with atmospheric bomb peak. Random offsets were observed specific activity samples...

10.1016/j.scitotenv.2021.152044 article EN cc-by-nc-nd The Science of The Total Environment 2021-11-30

Unrecorded alcohol has been linked to illness above and beyond that caused by ethanol alone because of the presence toxic contaminants. While it can be found in all countries, consumption is high Albania, where frequently consumed as a fruit brandy known rakia. Among contaminants identified previously such products, metals including lead have detected at levels posing risk health but there little information on their To fill this gap, we measured level 24 elements among them 30 Albanian...

10.1016/j.heliyon.2023.e13717 article EN cc-by-nc-nd Heliyon 2023-02-15

The glucocorticoid betamethasone (BM) has potent anti-inflammatory and immunosuppressive effects; however, it increases the susceptibility of patients to superficial Candida infections. Previously we found that this disadvantageous side effect can be counteracted by menadione sodium bisulfite (MSB) induced oxidative stress treatment. fungus specific protein phosphatase Z1 (CaPpz1) a pivotal role in response albicans was proposed as potential antifungal drug target. aim study investigate...

10.3390/jof7070540 article EN cc-by Journal of Fungi 2021-07-06

Abstract Anthropic activities related to urbanization release pollutants, including potentially toxic elements, into the atmosphere and these are eventually deposited in soils, water, infrastructures, vegetation. Urban soil plant leaves widely used as ecological indicators assess effect of urbanization. This study aimed evaluate impact based on elemental concentration Tilia × europaea from urban, suburban, rural areas along an gradient Debrecen, Hungary. Using ICP-OES technique, we measured...

10.1101/2024.04.17.589890 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-04-17
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