David P. Labeda

ORCID: 0000-0001-7311-9166
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Genomics and Phylogenetic Studies
  • Plant Disease Resistance and Genetics
  • Microbial Natural Products and Biosynthesis
  • Plant Pathogens and Fungal Diseases
  • Actinomycetales infections and treatment
  • Microbial Community Ecology and Physiology
  • Mycorrhizal Fungi and Plant Interactions
  • Probiotics and Fermented Foods
  • Infectious Diseases and Mycology
  • Plant Pathogens and Resistance
  • Mycobacterium research and diagnosis
  • Microbial Metabolic Engineering and Bioproduction
  • Identification and Quantification in Food
  • Plant-Microbe Interactions and Immunity
  • Plant and Fungal Species Descriptions
  • Microbial Metabolism and Applications
  • Enzyme Catalysis and Immobilization
  • Legume Nitrogen Fixing Symbiosis
  • Fungal Biology and Applications
  • Enzyme Production and Characterization
  • Enterobacteriaceae and Cronobacter Research
  • Protist diversity and phylogeny
  • Diatoms and Algae Research
  • Infections and bacterial resistance
  • Marine Sponges and Natural Products

Alameda Hospital
2021

National Center for Agricultural Utilization Research
2009-2018

Agricultural Research Service
2005-2017

United States Department of Agriculture
1989-2017

Agricultural Research Service - Midwest Area
2011

Illinois Department of Agriculture
2001-2009

Agricultural Research Service - Plains Area
2001

Illinois State University
1997

University of Alabama at Birmingham
1986

Rutgers, The State University of New Jersey
1985-1986

We propose two new genera, Amycolata and Amycolatopsis, to accommodate nocardioform actinomycetes having type IV cell wall composition lacking mycolic acids. These genera are distinguished from each other by phospholipid menaquinone phage sensitivity. The following species were assigned the genus Amycolata: autotrophica comb. nov. (type strain, strain ATCC 19727), saturnea NRRL B16172), hydrocarbonoxydans B16171). Amycolatopsis includes orientalis 19795), subsp. lurida nom. rev., nov.,...

10.1099/00207713-36-1-29 article EN International Journal of Systematic Bacteriology 1986-01-01

Microbes hold the key to life. They secrets our past (as descendants of earliest forms life) and prospects for future we mine their genes solutions some planet's most pressing problems, from global warming antibiotic resistance). However, piecemeal approach that has defined efforts study microbial genetic diversity over 20 years in 30,000 genome projects risks squandering promise. These have covered less than 20% cultured archaeal bacterial species, which represent just 15% overall known...

10.1371/journal.pbio.1001920 article EN cc-by PLoS Biology 2014-08-05

Significance The discovery of natural products, an important source human medicines, is critical for the development new therapeutics against health threats, including cancer and multidrug-resistant pathogens. Yet, in recent years, industrial pharmaceuticals from products has been stymied due to a variety reasons, repeated previously known compounds. Here, we demonstrate large-scale genomics as one potential solution this problem by mining collection 10,000 actinomycetes novel phosphonic...

10.1073/pnas.1500873112 article EN Proceedings of the National Academy of Sciences 2015-08-31

Listeria monocytogenes is a food-borne pathogen capable of growth at refrigeration temperatures. Membrane lipid fatty acids are major determinants sufficiently fluid membrane state to allow low L. was characterized by acid profile dominated an unusual extent (> 95%) branched-chain acids, with the being anteiso-C15:0, anteiso-C17:0, and iso-C15:0 in cultures grown complex or defined media 37 degrees C. Determination composition 10403S SLCC 53 over temperature range 45 5 C revealed two...

10.1128/aem.63.10.3887-3894.1997 article EN Applied and Environmental Microbiology 1997-10-01

Phosphonates, molecules containing direct carbon-phosphorus bonds, compose a structurally diverse class of natural products with interesting and useful biological properties. Although their synthesis in protozoa was discovered more than 50 y ago, the extent diversity phosphonate production nature remains poorly characterized. The rearrangement phosphoenolpyruvate (PEP) to phosphonopyruvate, catalyzed by enzyme PEP mutase (PepM), is shared vast majority known biosynthetic pathways. Thus, pepM...

10.1073/pnas.1315107110 article EN Proceedings of the National Academy of Sciences 2013-12-02

Abstract Many genomes are incorrectly identified at GenBank. We developed a plan to find and correct misidentified using genomic comparison statistics together with scaffold of reliably from type. A workshop was organized broad representation the bacterial taxonomic community review proposal, GenBank Microbial Genomic Taxonomy Workshop, Bethesda MD, May 12–13, 2015.

10.1186/s40793-016-0134-1 article EN cc-by Standards in Genomic Sciences 2016-02-09

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher we support invest in the microbiology community, to benefit of everyone. This supports our principal goal develop, expand strengthen networks available members so that they can generate new knowledge about microbes ensure it is shared with other communities.

10.1099/ijs.0.037366-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2011-11-01

The identification and classification of species within the genus Streptomyces is difficult because there are presently 576 with validly published names this number increases every year. value multilocus sequence analysis applied to systematics has been well demonstrated in several recently papers. In study fragments four housekeeping genes, atpD , recA rpoB trpB were determined for type strains 10 known phytopathogenic including scabiei acidiscabies europaeiscabiei luridiscabiei...

10.1099/ijs.0.028514-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2010-11-27

In phylogenetic analyses of the genus Streptomyces using 16S rRNA gene sequences, albus subsp . NRRL B-1811 T forms a cluster with five other species having identical or nearly sequences. Moreover, morphological and physiological characteristics these species, including almquistii B-1685 , flocculus B-2465 gibsonii B-1335 rangoonensis B-12378 are quite similar. This is particular taxonomic interest because type The related strains were subjected to multilocus sequence analysis (MLSA)...

10.1099/ijs.0.058107-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2013-11-26

Chemotaxonomic analysis of cells Streptomyces erythraeus NRRL 2338, the type strain species, revealed that this is not a representative genus because cell walls contain meso-diaminopimelic acid, arabinose, and galactose. I propose be transferred to Saccharopolyspora Lacey Goodfellow 1975 as new erythraea. The species erythraea described, 2338 (= ATCC 11635 = ISP 5517) designated strain. description amended, neotype strain, B-5616 IMRU 3737), proposed for species. A subspecies...

10.1099/00207713-37-1-19 article EN International Journal of Systematic Bacteriology 1987-01-01

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher we support invest in the microbiology community, to benefit of everyone. This supports our principal goal develop, expand strengthen networks available members so that they can generate new knowledge about microbes ensure it is shared with other communities.

10.1099/00207713-35-1-126b article EN International Journal of Systematic Bacteriology 1985-01-01

A species of the new genus Saccharothrix is described under name australiensis sp. nov. This aerobic characterized by fragmentation both vegetative and aerial mycelia into ovoid elements following novel cell chemistry: type III wall (meso-diaminopimelic acid present); galactose rhamnose present as characteristic whole-cell sugars; absence nocardomycolic acids; PII phospholipid pattern. The guanine-plus-cytosine content deoxyribonucleic 73 mol%. strain LL-BM782Ce82 (= ATCC 31947 = NRRL 11239).

10.1099/00207713-34-4-426 article EN International Journal of Systematic Bacteriology 1984-10-01

A polyphasic study was undertaken to establish the taxonomic status of Streptomyces strains isolated from hyper-arid Atacama Desert soils. Analysis 16S rRNA gene sequences isolates showed that they formed a well-defined lineage loosely associated with type several species. Multi-locus sequence analysis based on five housekeeping alleles form homogeneous taxon is closely related ghanaensis and viridosporus. Representative were shown have chemotaxonomic morphological properties consistent...

10.1007/s10482-017-0886-7 article EN cc-by Antonie van Leeuwenhoek 2017-06-06

Partial sequences for 16S rDNA were determined strains of the genus Saccharothrix, including most described species, as well species related genera Kutzneria, Actinokineospora and Actinosynnema. These aligned with published other these genera, those 'Actinoalloteichus', 'Asiosporangium', Lentzea, Streptoalloteichus representative taxa from actinomycete families. Phylogenetic analysis sequence data showed that Actinokineospora, Actinosynnema, Lentzea Saccharothrix are members same clade,...

10.1099/00207713-50-1-331 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2000-01-01

The genus Saccharothrix is phylogenetically heterogeneous on the basis of analysis almost complete 16S rDNA sequences. An evaluation chemotaxonomic, morphological and physiological properties in light molecular phylogeny data revealed that several species are misclassified. aerocolonigenes NRRL B-3298T flava B-16131T constitute a lineage distinct from separate Lentzea. Lechevalieria gen. nov. proposed for these species. comb. type S. transferred as Although Lentzea albidocapillata, Lentzea,...

10.1099/00207713-51-3-1045 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2001-05-01

ABSTRACT Evidence for the horizontal transfer of a pathogenicity island (PAI) carrying virulence gene nec1 and flanking sequences among Streptomyces strains in Diastatochromogenes cluster is presented. Plant-pathogenic, thaxtomin-producing strains, previously classified as S. scabiei based on conventionally used phenotypic characteristics, were found to be genetically distinct from type strain DNA relatedness 16S rDNA sequence analysis. Pairwise DNA-DNA hybridizations between some these low...

10.1128/aem.68.2.738-744.2002 article EN Applied and Environmental Microbiology 2002-02-01

We describe two species of the new genus Glycomyces, Glycomyces harbinensis sp. nov. and rutgersensis Members this are aerobic, produce nonfragmenting vegetative hyphae, form chains conidia on aerial sporophores. The cell walls type II (meso-diaminopimelic acid glycine present), whole-cell sugar patterns D (xylose arabinose present). phospholipid pattern both is P-I (no nitrogenous phospholipids). guanine-plus-cytosine content deoxyribonucleic ranges from 71 to 73 mol%. strain G. NRRL 15337...

10.1099/00207713-35-4-417 article EN International Journal of Systematic Bacteriology 1985-10-01

The taxonomic status of the families Actinosynnemataceae and Pseudonocardiaceae was assessed based on 16S rRNA gene sequence data available for 151 taxa with validly published names, as well chemotaxonomic morphological properties from literature. sequences type strains all within suborder Pseudonocardineae were subjected to phylogenetic analyses using different algorithms in arb phylip. description many new genera species since family proposed 2000 has resulted a markedly distribution...

10.1099/ijs.0.024984-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2010-07-03
Coming Soon ...