Stelios Tigas

ORCID: 0000-0001-7325-8983
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About
Contact & Profiles
Research Areas
  • Diabetes Management and Research
  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Diabetes Treatment and Management
  • Pituitary Gland Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Parathyroid Disorders and Treatments
  • Hormonal and reproductive studies
  • Hormonal Regulation and Hypertension
  • Ophthalmology and Eye Disorders
  • Diet and metabolism studies
  • Bone health and treatments
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Autoimmune Bullous Skin Diseases
  • Thyroid Disorders and Treatments
  • Cardiovascular Health and Disease Prevention
  • Vitamin D Research Studies
  • Bone health and osteoporosis research
  • Adipose Tissue and Metabolism
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Adrenal and Paraganglionic Tumors
  • Adipokines, Inflammation, and Metabolic Diseases
  • Neuroendocrine Tumor Research Advances
  • Bone Metabolism and Diseases
  • Metabolism, Diabetes, and Cancer

University of Ioannina
2016-2025

University Hospital of Ioannina
2014-2025

St Thomas' Hospital
2002-2005

Children's Nutrition Research Center at Baylor College of Medicine
2002-2003

Agricultural Research Service
2002-2003

Baylor College of Medicine
2002

United States Department of Agriculture
2002

Edinburgh Royal Infirmary
2000

Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was compare among using data gathered regional or national registries.Data were obtained for children and/or adults from the following countries (or regions): Western Australia, Austria, Denmark, England, Champagne-Ardenne (France), Germany, Epirus, Thessaly and Thessaloniki (Greece), Galway (Ireland), several Italian regions, Latvia, Rotterdam (The Netherlands), Otago (New Zealand), Norway,...

10.1111/dme.12676 article EN Diabetic Medicine 2014-12-15

Immune response following viral infections has been suggested as a probable mechanism leading to subacute thyroiditis (SAT). A few cases of SAT SARS-CoV-2 infection have described since the outbreak pandemic in 2019. Cases after vaccination against influenza also reported. We describe two female patients with SARS-CoV-2.The first patient presented fever and pain thyroid area typical weeks BNT162B2 mRNA (Pfizer-BioNTech) COVID-19 vaccine. The second biochemical imaging features consistent...

10.1016/j.metop.2021.100136 article EN cc-by-nc-nd Metabolism Open 2021-10-19

Type 2 diabetes mellitus (T2DM) is independently associated with an increased risk for cardiovascular diseases that primarily due to the early development of advanced atherosclerotic vascular changes. The aim our study was investigate predictors dysfunction in T2DM patients.We studied 165 patients without known macrovascular or microvascular disease. Standard demographic (age, gender, factors, medications), clinical (body mass index, blood pressure) and laboratory (glucose, glycated...

10.1186/1475-2840-11-127 article EN cc-by Cardiovascular Diabetology 2012-10-12

To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes.Data were obtained for 520,392 children adults diabetes from 17 population five clinic-based data sources countries or regions between 2016 2020. Median HbA1c (IQR) proportions individuals < 58 mmol/mol (<7.5%), 58-74 (7.5-8.9%) ≥75 (≥9.0%) compared populations aged <15, 15-24 ≥25 years. Logistic regression was used to estimate the odds ratio (OR) (<7.5%) relative ≥58...

10.1111/dme.14766 article EN Diabetic Medicine 2021-12-10

The aim of these studies was to determine the metabolic adaptation fasting and feeding during lactation. Normal lactating (L) nonlactating (NL) women (n = 6 each) were studied using infusions [U-13C]glucose [2-13C]glycerol during: 1) a 24-h fast, 2) ingestion Sustacal (protocol 1). In addition, 8 L NL infusion [6,6-2H2]glucose glucose meal containing [1-13C]glucose 2). Protocol 1: Glucose production rate (GPR) 33% higher in (12.5 ± 1.0 vs. 9.4 0.5 μmol·kg−1·min−1; P < 0.03). Fractional...

10.1210/jcem.87.1.8178 article EN The Journal of Clinical Endocrinology & Metabolism 2002-01-01

Diet, physical activity, sleep and smoking have been individually associated with glycemic control (GC) in adults type 1 diabetes mellitus (T1D). However, the combined effect of these factors has not investigated. The aim present study was to examine single effects lifestyle parameters on GC people T1D (PwT1D). Dietary, activity habits were evaluated using validated questionnaires. Diet quality assessed two scores (MedDietScore PURE Score) healthy indices (HLI) constructed (MLI based...

10.1016/j.numecd.2025.103868 article EN cc-by Nutrition Metabolism and Cardiovascular Diseases 2025-01-01

Type 1 diabetes (T1D) is a chronic endocrine disorder characterized by high blood glucose levels, impacting millions of people globally. Its management requires intensive insulin therapy, frequent monitoring, and lifestyle adjustments. The accurate prediction the short-term course levels in subcutaneous space T1D people, as measured continuous monitoring (CGM) system, essential for improving control avoiding harmful hypoglycaemic hyperglycaemic swings, facilitating precise individualized...

10.1186/s12911-025-02867-2 article EN cc-by-nc-nd BMC Medical Informatics and Decision Making 2025-01-31

Hyperprolactinaemia as a side effect of dopamine receptor blockers is common in patients with schizophrenia and other psychotic disorders may lead to amenorrhoea, galactorrhoea, hypogonadism, subfertility osteoporosis. The aim our study was determine whether hyperprolactinaemia occurs also prior any antipsychotic treatment.Serum prolactin, thyroid-stimulating hormone (TSH), triiodothyronine (T3), free tetraiodothyronine (FT4) cortisol levels were measured 40 newly diagnosed, drug naïve, age...

10.1080/13651501.2016.1197274 article EN International Journal of Psychiatry in Clinical Practice 2016-06-23

Background: Obesity is associated with macrophage infiltration in adipose tissue that induces insulin resistance and contributes to the development of metabolic syndrome (MS). The aim this study was investigate whether circulating monocyte subsets (macrophage precursors) differ among obese subjects MS [metabolically unhealthy (MUO)], without healthy (MHO)], metabolically lean (MHL) individuals. Methods: Fifty-eight (33 MUO, 25 MHO) MHL individuals participated study. Absolute blood counts...

10.1089/met.2018.0132 article EN Metabolic Syndrome and Related Disorders 2019-03-13

There is controversy about the correct dose and form of thyroid hormone therapy for patients with hypothyroidism. Despite restoration serum thyrotropin (TSH) concentrations to normal, many complain excessive weight gain. We have compared at diagnosis hyperthyroidism that when euthyroid, evidenced by a stable, normal TSH concentration, or without thyroxine (T4) replacement therapy, in treated an 18-month course antithyroid drugs (43 patients), surgery (56 13I (34 patients) Graves' disease. In...

10.1089/thy.2000.10.1107 article EN Thyroid 2000-12-01

Lactose is the major osmotic agent in milk. Therefore, lactose synthesis indirectly regulates milk volume. The aim of this study was to determine source glucose and galactose lactose. Six healthy lactating women were studied twice, during a 24-h fast ingestion mixed macronutrient drink (Sustacal) using [U-13C]glucose [2-13C]glycerol. additional on one single occasion labeled with [1-13C]glucose. Using ratios [13C6] enrichments plasma that glucose, we determined 98 +/- 3% 68 7% derived from...

10.1210/jcem.87.1.8171 article EN The Journal of Clinical Endocrinology & Metabolism 2002-01-01
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