A5059345106- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
- Adrenal Hormones and Disorders
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Hormonal Regulation and Hypertension
- Hormonal and reproductive studies
- Cancer, Hypoxia, and Metabolism
- Metabolism, Diabetes, and Cancer
- Neuroblastoma Research and Treatments
- Hematological disorders and diagnostics
- Pancreatic function and diabetes
- Bone and Joint Diseases
- Parathyroid Disorders and Treatments
- Cell Adhesion Molecules Research
- Vitamin K Research Studies
- Dermatological and COVID-19 studies
- Bone health and treatments
- Pharmacological Effects and Toxicity Studies
- Byzantine Studies and History
- Hypothalamic control of reproductive hormones
- Myasthenia Gravis and Thymoma
- Nuclear Structure and Function
- Electrolyte and hormonal disorders
General Hospital of Athens G. Genimatas
2022-2025
University of Birmingham
2016-2024
University Hospitals Birmingham NHS Foundation Trust
2018-2024
Queen Elizabeth Hospital
2018-2024
HealthPartners
2024
Queen Elizabeth Hospital Birmingham
2017-2021
University Hospital of Ioannina
2015-2019
University of Ioannina
2014-2018
Evangelismos Hospital
1981
Plasma fibronectin was determined in 121 normal adults and 149 patients. Fibronectin levels normals were strongly influenced by sex age. The mean value of the protein cancer patients did not differ from that controls; however, with cryofibrinogenaemia or extensive liver metastases had lower values whereas those obstructive jaundice due to pancreatic carcinoma higher than controls. greatly increased primary biliary cirrhosis moderately elevated nephrotic syndrome. In severe infection sepsis,...
Abstract Objective The optimal approach to the surveillance of non-functioning pituitary microadenomas (micro-NFPAs) is not clearly established. Our aim was generate evidence on natural history micro-NFPAs support patient care. Design Multi-centre, retrospective, cohort study involving 23 endocrine departments (UK NFPA consortium). Methods Clinical, imaging, and hormonal data micro-NFPA cases between January, 1, 2008 December, 21, 2021 were analysed. Results Data for 459 patients retrieved...
Introduction Adrenal tumors (ATs) encompass a wide differential diagnosis, necessitating multi-step process for accurate identification. Liquid biopsy emerges as promising non-invasive technique distinguishing between malignant and benign, well hyperfunctioning non-functioning cases. Recent studies have highlighted the potential of microRNAs circulating biomarkers; however, their clinical utility remains underexplored. This study aims to validate diagnostic performance selected microRNAs,...
Long-term outcomes of patients with Nelson's syndrome (NS) have been poorly explored, especially in the modern era.To elucidate tumor control rates, effectiveness various treatments, and markers prognostic relevance NS.Retrospective cohort study 68 from 13 UK pituitary centers median imaging follow-up years (range 1-45) since NS diagnosis.Management Cushing's disease (CD) prior to diagnosis included surgery+adrenalectomy (n = 30; eight had 2 one 3 operations),...
Discontinuation of dopamine agonist (DA) treatment in women with prolactinoma after menopause is a potential approach; studies systematically assessing long-term outcomes are lacking. Our aim was to investigate the natural history this group.Retrospective cohort study diagnosed before and who were not on DA.Thirty included. Twenty-eight received DA (median duration 18 years, median age at withdrawal 52 years). At last assessment follow-up 3 years) compared values 6-12 months stopping DA,...
Proteinuric renal disease is prevalent in congenital or acquired forms of generalized lipodystrophy. In contrast, an association between familial partial lipodystrophy (FPLD) and has been documented very few cases. A 22-year-old female patient presented with impaired glucose tolerance, hyperinsulinemia, hirsutism oligomenorrhea. On examination, there was loss subcutaneous adipose tissue the face, upper lower limbs, bird-like facies micrognathia low set ears mild acanthosis nigricans....
Branched-chained amino acids (BCAA) are essential dietary components for humans and can act as potential biomarkers diabetes development. To efficiently estimate intake, we developed a BCAA database 1331 food items found in the French Centre d’Information sur la Qualité des Aliments (CIQUAL) table by compiling content from international tables, published measurements, or similarity well calculating 267 Greek, Turkish, Romanian, Moroccan mixed dishes. The embedded MEDIPAD software capable of...
Summary Co-existence of craniopharyngioma and acromegaly has been very rarely reported. A 65-year-old man presented with visual deterioration, fatigue frontal headaches. Magnetic resonance imaging revealed a suprasellar heterogeneous, mainly cystic, 1.9 × 2 cm mass compressing the optic chiasm expanding to third ventricle; findings were consistent craniopharyngioma. Pituitary hormone profile showed hypogonadotropic hypogonadism, mildly elevated prolactin, increased insulin-like growth factor...
A 45 year old man was admitted to hospital with rapid onset headache, fever, confusion, photophobia, and hypotension. His wife confirmed a six month history of frequent headaches relieved by analgesics. Neck stiffness identified on clinical examination. He had no signs water retention (ankle pitting oedema) or dehydration (dry mucous membrane, reduced skin elasticity). Initial biochemical evaluation showed raised inflammatory markers hyponatraemia. Renal liver function tests were within...