A5100364331- Advanced biosensing and bioanalysis techniques
- Plant Molecular Biology Research
- MicroRNA in disease regulation
- Gene expression and cancer classification
- Biosensors and Analytical Detection
- Circular RNAs in diseases
- Plant biochemistry and biosynthesis
- Bioenergy crop production and management
- Plant Gene Expression Analysis
- Molecular Biology Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Epigenetics and DNA Methylation
- Machine Learning in Bioinformatics
- Traditional and Medicinal Uses of Annonaceae
- Bioinformatics and Genomic Networks
- Synthetic Organic Chemistry Methods
- Cancer Mechanisms and Therapy
- RNA Research and Splicing
- Developmental Biology and Gene Regulation
- Biotin and Related Studies
- Natural Antidiabetic Agents Studies
- Silk-based biomaterials and applications
- Pesticide Residue Analysis and Safety
- SARS-CoV-2 detection and testing
- Extracellular vesicles in disease
Shenzhen Institutes of Advanced Technology
2025
Chinese Academy of Sciences
2023-2025
Life & Brain (Germany)
2024
Research Institute of Forestry
2024
Chinese Academy of Forestry
2024
Nanjing Normal University
2024
University of Bonn
2024
Czech Academy of Sciences, Institute of Physiology
2024
Dalian University of Technology
2017-2023
Institute of Soil Science
2023
Abstract Wood formation involves consecutive developmental steps, including cell division of vascular cambium, xylem expansion, secondary wall (SCW) deposition, and programmed death. In this study, we identified PagMYB31 as a coordinator regulating these processes in Populus alba × glandulosa built PagMYB31-mediated transcriptional regulatory network. mutation caused fewer layers cambial cells, larger fusiform initials, ray vessels, fiber enhanced SCW thickening, showing that positively...
Feature selection is an important topic in bioinformatics. Defining informative features from complex high dimensional biological data critical disease study, drug development, etc. Support vector machine-recursive feature elimination (SVM-RFE) efficient technique that has shown its power many applications. It ranks the according to recursive deletion sequence based on SVM. In this we propose a method, SVM-RFE-OA, which combines classification accuracy rate and average overlapping ratio of...
Asymmetric total synthesis of the dimeric diterpenoid hispidanin A was accomplished by non-catalytic Diels-Alder cycloaddition at room temperature. The relies on iron-catalyzed coupling to construct a Z-configured trisubstituted alkene, an radical cascade generate labdane-type diene, and both Yamamoto cationic polyene cyclization palladium-catalyzed Stille totarane-type dienophile.
Abstract Aims Endothelial cell (EC) dysfunction plays a key role in the initiation and progression of cardiovascular disease. However, studying these disorders ECs from patients is challenging; hence, use human induced pluripotent stem cells (hiPSCs) their vitro differentiation into represents very promising approach. Still, generation hiPSC-derived (hECs) remains demanding as cocktail growth factors an intermediate purification step are required for hEC enrichment. Therefore, we probed...
Nontargeted analysis is a useful strategy for the discovery of unknown risk compounds. However, how to rapidly screen and determine substances still big challenge. In this study based on high-performance liquid chromatography (HPLC)–high resolution mass spectrometry (HRMS), rapid screening determination was established. First, distribution characteristic every feature from HRMS in all samples studied by mean deviation ratio (MDR) calculation. Features with MDR more than 20 were thought be...
Vasculogenic mimicry (VM) is linked to vascular invasion of human hepatocellular carcinoma (HCC).BMP4, one BMP family member, upregulated in several cancers.The purpose this report identify the function BMP4 formation VM HCC and mechanism underling regulation.In our report, up-regulation resulted an increase migration, channel-like structure as well induced epithelial-mesenchymal transition (EMT) process stem cell-associated proteins OCT4 SOX2 expression cells.In addition, The VM-associated...
The transcription factor AP2 (TFAP2) has an important role in regulating gene expression both epidermis and neural crest cells. In order to further characterize these functions we have used a hormone inducible TFAP2α fusion protein Xenopus animal cap assay identify downstream targets of this factor. most common pattern comprised genes predominantly expressed the epidermis. A second group was at high levels crest, but all were also as well other tissues which not been detected, suggesting...
Abstract Asymmetric total synthesis of the dimeric diterpenoid hispidanin A was accomplished by non‐catalytic Diels–Alder cycloaddition at room temperature. The relies on iron‐catalyzed coupling to construct a Z ‐configured trisubstituted alkene, an radical cascade generate labdane‐type diene, and both Yamamoto cationic polyene cyclization palladium‐catalyzed Stille totarane‐type dienophile.
Reverse Transcription quantitative polymerase chain reaction (RT-qPCR) is a sensitive and reliable method for mRNA quantification rapid analysis of gene expression from large number starting templates. It based on the statistical significance beginning exponential phase in real-time PCR kinetics, reflecting cycle initial target quantity efficiency (the fold increase product per cycle).
A Gram-negative and rod-shaped bacterium, designated C340-1
Abstract Poly(aniline‐luminol‐hemin) nanocomposites are prepared on an electrode surface through electropolymerization, and a highly sensitive electrochemiluminescence (ECL) biosensor for choline is developed based the poly(aniline‐luminol‐hemin) enzyme catalyzed reaction of oxidase (CHOD). The obtained characterized by scanning electron microscopy (SEM), atomic absorption spectrometry (AAS) ECL. results indicate that hemin can be incorporated into poly(aniline‐luminol) using facile...
Abstract A novel electrochemiluminescence biosensor was presented for the assay of hepatitis B virus (HBV) DNA. Coralloid poly(aniline‐luminol)‐MWCNTs prepared on an electrode surface, which followed by attachment capture DNA via amide bond formation. The HBV‐DNA and ferrocene labelled hybridized with to form a sandwich structure surface. Ferrocene can effectively increase signal output ECL sensor due catalysis luminol. rendered linear dependence over range from 1.0×10 −16 −7 M low detection...
The tumor suppressor p53, which acts primarily as a transcription factor, can regulate infections from various viruses in chickens. However, the underlying mechanisms of antiviral functions chicken p53 (chp53) remain unclear due to lack detailed information on its transcriptional regulation. Here, gain comprehensive insights into chp53 regulatory function global and unbiased manner, we determined genome-wide chromatin occupancy by immunoprecipitation, was followed sequencing chp53-mediated...
Luminol and hemin dual-functionalized silica nanoparticles were synthesized using a typical reverse water-in-oil microemulsion protocol. The obtained further characterized by transmission electron microscopy, scanning atomic absorption spectrometry, chemiluminescence, electrochemiluminescence. results indicated that the luminol exhibited significantly higher chemiluminescence electrochemiluminescence intensities than those of functionalized due to catalytic effect on luminol. Furthermore,...
Abstract Background and aims Both straw incorporation water management affect biological nitrogen fixation (BNF), but it is unclear how impact the effects of returning on BNF diazotrophs in rice fields. Methods A 15 N 2 -labelling system was used to determine under with continuous or intermittent flooding field for 90 days. The nitrogenase nifH gene RNA (cDNA) were amplified by qPCR community structure diazotroph studied high-throughput sequencing DNA gene. Results Combined incorporation,...