Zhang Jian-min

ORCID: 0000-0001-7515-1098
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Traditional Chinese Medicine Analysis
  • Medical Research and Treatments
  • Hemodynamic Monitoring and Therapy
  • Chromatography in Natural Products
  • Intensive Care Unit Cognitive Disorders
  • Pharmacy and Medical Practices
  • Pediatric Pain Management Techniques
  • Congenital Diaphragmatic Hernia Studies
  • Airway Management and Intubation Techniques
  • Respiratory Support and Mechanisms
  • Shoulder Injury and Treatment
  • Plant-based Medicinal Research
  • Neonatal Respiratory Health Research
  • Central Venous Catheters and Hemodialysis
  • Pharmacological Effects of Natural Compounds
  • Traditional Chinese Medicine Studies
  • Medicinal Plant Pharmacodynamics Research
  • Hepatitis B Virus Studies
  • Viral Infections and Vectors
  • Nausea and vomiting management
  • Intestinal Malrotation and Obstruction Disorders

Children's Hospital of Capital Institute of Pediatrics
2024-2025

Soochow University
2024

Beijing Children’s Hospital
2010-2024

Capital Medical University
2009-2024

Yunnan University
2009-2024

China Earthquake Administration
2024

Wenzhou Medical University
2016-2024

Northwest Institute of Nuclear Technology
2015-2017

Zhejiang Taizhou Hospital
2016

Nanyang Technological University
2016

Background Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective observational study sought to determine the prevalence of EEG young children during anesthesia. The authors hypothesized that events would be common worldwide certain anesthetic practices intraoperative hypotension. Methods Fifteen hospitals enrolled patients age 36 months or younger for surgery using sevoflurane propofol...

10.1097/aln.0000000000004262 article EN Anesthesiology 2022-05-03

Pediatric clinical trials face many challenges that hinder the development of safe and effective pediatric drugs. Enhancing risk control management quality in research centers is essential to address these challenges. While existing studies focus on from perspective sponsors, specifically addressing strategies limited. There a lack systematic exploration expert consensus risk-based system for institutions. This study seeks fill this gap by developing assessment index designed enhance...

10.1186/s12887-025-05513-y article EN cc-by-nc-nd BMC Pediatrics 2025-03-31

The use of the bispectral index (BIS) is widespread in pediatric anesthesia, but few studies have attempted to perform a detailed evaluation how BIS varies according age children under propofol anesthesia. This prospective study aimed explore exact relationship between value and 1- 12-year-old enrolled 165 (1 < yr. ≤ 12), scheduled for surgery divided them into 11 groups. Of participants, 157 completed protocol. All patients were anesthetized with over 30 s. An observation period 4 min...

10.1186/s12871-019-0815-6 article EN cc-by BMC Anesthesiology 2019-08-07

Although the effects of family on performance are well documented in literature entrepreneurship, few accounts explore underlying mechanism influence that has female entrepreneurial performance. We divide factors into demands and resources develop a conceptual framework to mediating family–work relationships moderating roles two boundary attributes relationship between Our research conducted western China reveals have negative effect while positive effect; partially mediate performance;...

10.1080/1540496x.2019.1697671 article EN Emerging Markets Finance and Trade 2019-12-18

Summary Background Although some studies have investigated the potential predictors of perioperative mortality, there are few specifically for pediatrics. Objective The aim retrospective study was to analyze preoperative risk factors and develop a pediatric prediction score ( PRPS ), predict postoperative ICU admission incidence death in patients. Methods Patients who postoperatively admitted or died (occurred within 30 days after surgery) from 263 607 surgical patients with age 1 day 14...

10.1111/pan.12905 article EN Pediatric Anesthesia 2016-04-27

Although regional cerebral oxygen saturation (rScO2) monitoring has been widely used in clinical practice, the relationship between hemoglobin (dHB) content and rScO2 is incompletely understood. The aim of this study was to analyze effect on pediatric patients undergoing general anesthesia for correction scoliosis.Ninety-two aged 3 14 years scoliosis surgery were enrolled. Continuous bilateral by near-infrared spectroscopy (NIRS, CASMED, USA) performed after entering operation room. recorded...

10.1186/s12871-021-01382-x article EN cc-by BMC Anesthesiology 2021-06-01

There is currently no consensus on the optimal perioperative pain management strategy involving specific opioids. This study aims to compare postoperative analgesia, associated side effects between nalbuphine and morphine in children undergoing laparoscopic surgery. One hundred ninety were randomly assigned (0.2 mg/kg) or mg/kg). Nalbuphine's analgesic effect was non-inferior morphine, with similar total rescue consumption during PACU stay (0.03 ± 0.05mg vs. 0.04 0.06 mg, p > 0.05)....

10.1016/j.isci.2024.109287 article EN cc-by-nc iScience 2024-02-20

Objective: There is no universal agreement on optimal pharmacological regimens for pain management during surgeries. The aim of this study to compare the postoperative analgesic effects nalbuphine with fentanyl in children undergoing adenotonsillectomy. Design, Setting, Participants: We conducted a prospective, randomized, double-blind, non-inferiority and multicenter trial 311 patients admitted four different medical facilities China from October 2017 November 2018. Main Outcome Measure:...

10.3389/fphar.2020.597550 article EN cc-by Frontiers in Pharmacology 2020-12-09

Pediatric medication is a challenging issue globally. Promoting trials of medications for children and implementing measures to encourage innovation addressing unmet medical health needs are important.

10.1002/ped4.12409 article EN cc-by-nc-nd Pediatric Investigation 2024-01-03

Drowning is a common cause of childhood morbidity and mortality worldwide. Anoxia, hypothermia, metabolic acidosis are mainly responsible for this morbidity. may lead to multiple organ damage, especially cardiac in cases which severe hypothermia hypoxemia occur. We report case 4-year-old girl who was admitted our hospital's Emergency Department because drowning. She had elevated troponin I concentrations ST-segment elevation with T wave inversion. However, cardiovascular computed tomography...

10.1177/03000605241233516 article EN cc-by-nc Journal of International Medical Research 2024-03-01

Abstract Background Inadequate postoperative pain management increases the risk of adverse events after surgery and aggressive perioperative prevention has both short-term long-term benefits. S(+)-ketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with a strong analgesic effect can significantly relieve acute reduce opioid consumption. However, for children, it still needs to be confirmed by large sample clinical studies. Methods This pragmatic, randomized controlled trial...

10.1186/s13063-022-06534-z article EN cc-by Trials 2022-07-23

It is believed that negative postoperative behavioral changes (NPOBC) associated with perioperative outcomes in children. The importance of development a predictive model NPOBC was noted. This study aims to identify potential risk factors develop nomogram predict on day 3 based prospective cohort.A observational conducted children(American Society Anesthesiologists I ~ III) aged 2 12 years who underwent selective surgery under general anesthesia between September 2022 and February 2023....

10.1186/s12871-023-02228-4 article EN cc-by BMC Anesthesiology 2023-08-04

In children, anesthesia dosages are based on population pharmacokinetics and patient hemodynamics rather than patient-specific brain activity. Brain function is highly susceptible to the effects of anesthetics.

10.1002/ped4.12287 article EN cc-by-nc-nd Pediatric Investigation 2021-08-16

In this article, an overview of laser dazzling effect to buried channel CCD camera is given. The CCDs are sorted into staring and scanning types. former includes the frame transfer interline latter linear time delay integration All must perform four primary tasks in generating image, which called charge generation, collection, measurement. camera, lenses needed input optical signal sensors, techniques for erasing stray light used. And electron circuits process output CCD, many electronic...

10.1117/12.2178366 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2015-05-04

This study described electroencephalogram (EEG) parameters in children under general anesthesia, which could monitor patient-specific brain responses to anesthetics and assess the effects of anesthesia. The objective was detect patient state index (PSI) associated factors. We analyzed EEG patients age range 1 36 months. Patients were stratified into 2 groups as those aged 12 months 13 Sixty-two involved. Spectral edge frequency (SEF), PSI, blood pressure lower, burst suppression rate (BSR)...

10.1177/00099228231168475 article EN Clinical Pediatrics 2023-04-11

Abstract Background The use of the bispectral index (BIS) is widespread in pediatric anesthesia, but few studies have attempted to perform a detailed evaluation how BIS varies according age children under propofol anesthesia. This prospective study aimed explore exact relationship between value and 1- 12-year-old Methods enrolled 165 (1&lt;0.01) as well among different groups (p&lt;0.01) after administration. Post-hoc Bonferroni tests showed difference values 1–4 (1

10.21203/rs.2.9256/v3 preprint EN cc-by Research Square (Research Square) 2019-08-13
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