A5045306835- Sleep and Wakefulness Research
- Sleep and related disorders
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Circadian rhythm and melatonin
- Restless Legs Syndrome Research
- Psychotherapy Techniques and Applications
- Mind wandering and attention
- Epilepsy research and treatment
- Obstructive Sleep Apnea Research
- Psychosomatic Disorders and Their Treatments
- Neurology and Historical Studies
- Health, Medicine and Society
- Health and Medical Studies
- Psychoanalysis and Psychopathology Research
- Mental Health and Psychiatry
- Medical and Health Sciences Research
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Neuroscience of respiration and sleep
- Hallucinations in medical conditions
- Eating Disorders and Behaviors
- Cerebrovascular and genetic disorders
- Child Therapy and Development
University Hospital of Geneva
2013-2025
University of Geneva
2013-2025
Hôpital Beau-Séjour
2022-2023
HES-SO Genève
2023
University of Wisconsin–Madison
2014-2019
Geneva College
2015-2019
Sleep Research Society
2015-2016
University of Wales
2014
Cambridge Cognition (United Kingdom)
2013
Abstract Why do people sometimes report that they remember dreams, while at other times recall no experience? Despite the interest in dreams may happen during night, it has remained unclear which brain states determine whether these conscious experiences will occur and what prevents us from waking up episodes. Here we address this issue by comparing EEG activity preceding awakenings with recalled vs. of using microstate approach. This approach characterizes transiently stable sub-second...
Recent studies in sleep and dreaming have described an activation of emotional reward systems, as well the processing internal information during these states. Specifically, increased activity amygdala across mesolimbic dopaminergic regions REM is likely to promote consolidation memory traces with high emotional/motivational value. Moreover, coordinated hippocampal-striatal replay NREM may contribute selective strengthening memories for important events. In this review, we suggest that, via...
Thoughts occur during wake as well dreaming sleep. Using experience sampling combined with high-density EEG, we investigated the phenomenal qualities and neural correlates of spontaneously occurring thoughts across wakefulness, non-rapid eye movement (NREM) sleep, REM Across all states, were associated activation a region midcingulate cortex. wakefulness additionally involved medial prefrontal region, which was metacognitive wake. Phenomenologically, waking had more content than both NREM...
Nightmares are characterized by the experience of strong negative emotions occurring mainly during REM sleep. Some people suffer from nightmare disorder, which is defined repeated occurrence nightmares and significant distress in wakefulness. Yet, whether frequent relate to a general increase emotional reactivity or arousal sleep remains unclear. To address this question, we recorded heartbeat-evoked potentials (HEPs) wakefulness, NREM patients with disorder healthy participants. The HEP...
Recent neuroscientific theories have proposed that emotions experienced in dreams contribute to the resolution of emotional distress and preparation for future affective reactions. We addressed one emerging prediction, namely experiencing fear is associated with more adapted responses threatening signals during wakefulness. Using a stepwise approach across two studies, we identified brain regions activated when showed frightening modulated response these same stimuli Specifically, Study 1,...
Summary According to some theories of emotion regulation, dreams could modify negative emotions and ultimately reduce their intensity. We introduce here the idea cathartic dream , a specific separate type emotional dream, which is characterized by dynamic plot with twists, where are expressed decreased. This process would reflect psychological relief (catharsis according Aristotelian definition) fulfil an regulation function. developed validated tool using large language model emotionally...
Functional dissociations in the brain observed during non-rapid eye movement (NREM) sleep have been associated with reduced information integration and impaired consciousness that accompany increasing depth. Here, we explored dynamical properties of large-scale functional networks derived from transient activity using magnetic resonance imaging. Spatial maps generally display significant modifications terms their tendency to occur across wakefulness NREM sleep. Unexpectedly, almost all...
Social anxiety disorder (SAD) is characterized by a significant amount of fear when confronted to social situations. Exposure therapy, which based on extinction, does not often lead full remission. Here, evidence showing that rapid eye movement (REM) sleep promotes the consolidation extinction memory, we used targeted memory reactivation (TMR) during REM enhance learning in SAD.Forty-eight subjects with SAD were randomly assigned two groups: control or TMR group. All patients had successive...
Abstract The function of dreams is a longstanding scientific research question. Simulation theories dream function, which are based on the premise that represent evolutionary past selective pressures and fitness improvement through modified states consciousness, have yet to be tested in cross-cultural populations include small-scale forager societies. Here, we analyze content with comparisons between BaYaka (Rep. Congo) Hadza (Tanzania) foraging groups Global North populations, test...
Investigate sleep and temporal lobe epilepsy (TLE) effects on brain networks derived from electroencephalography (EEG).
Background We previously suggested that abnormal sleep behaviors, i.e., as found in parasomnias, may often be the expression of increased activity reward system during sleep. Because nightmares and sleepwalking predominate REM NREM respectively, we tested here whether exploratory excitability, a waking personality trait reflecting high within mesolimbic dopaminergic (ML-DA) system, associated with specific changes patterns these two disorders. Methods Twenty-four unmedicated patients...
Consciousness never fades during wake. However, if awakened from sleep, sometimes we report dreams and no experiences. Traditionally, dreaming has been identified with REM characterized by a wake-like, globally ‘activated’, high-frequency EEG. also occurs in NREM prominent low-frequency activity. This challenges our understanding of the neural correlates conscious experiences sleep. Using high-density EEG, contrasted presence absence within In both was associated local decrease activity...
A 61-year-old patient with alcohol use disorder (AUD) was referred for suspicion of sleep apnea syndrome (SAS). He had incurred three road accidents attributed to sleepiness over the previous year, shortly after initiation high-dose (100 mg b.i.d.) treatment baclofen, a molecule increasingly used in management AUD. Polysomnography revealed severe central SAS (CSAS) an apnea-hypopnea index (AHI) 81.6/h. Baclofen suggested as possible cause CSAS, and its withdrawal, second polysomnography...
The objectives of this study is to determine the knowledge, attitudes and experience psychiatric nurses regarding clients with Borderline Personality Disorder (BPD) compare working in Psychiatric Hospitals those Clinics General Hospitals. was performed two public area Greater Athens. 23-item questionnaire Cleary et al. used study. It sent all (n = 127) 15 wards. staff have good enough knowledge diagnosis treatment BPD patients. In (A) comes contact patients less frequently than (B)....
SUMMARY Despite partial experimental evidence, it is a long-standing and common belief that dreams serve an emotion regulation function. Revisiting this idea, recent neuroscientific theories have proposed emotions experienced in contribute to the resolution of emotional distress (e.g. fear extinction) preparation for future waking affective reactions. Here we addressed one emerging prediction from these theoretical accounts, namely experiencing associated with more adapted responses...
In this paper, we present two carefully documented cases of patients with sleep-related eating disorder (SRED), a parasomnia which is characterized by involuntary compulsive during the night and whose pathophysiology not known. Using video-polysomnography psychometric examination, found that both elevated novelty seeking increased reward sensitivity on reward-related questionnaires. light new evidence mesolimbic dopaminergic implication in disorders, our findings suggest role an active...
Magneto/electroencephalography (M/EEG) studies of dreaming are an essential paradigm in the investigation neurocognitive processes human consciousness during sleep, but they limited by number observations that can be collected per study. Dream research also involves substantial methodological and conceptual variability, which poses problems for integration results. To address these issues, here we present DREAM database—an expanding collection standardized datasets on sleep M/EEG combined...
There are some arguments that Friedrich Nietzsche suffered from the autosomal dominant vascular microangiopathy: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). Here, a hypothesis is formulated supporting CADASIL presenting symptoms of bipolar disorder Gastaut-Geschwind syndrome would contribute to increased insight creativity philosopher whose perceptions intuitions often bear out results modern neuroscience. Alterations brain default...