A5103145409- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- MRI in cancer diagnosis
- Advanced Radiotherapy Techniques
- Surgical Simulation and Training
- Soil Carbon and Nitrogen Dynamics
- Brain Tumor Detection and Classification
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Endometrial and Cervical Cancer Treatments
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiation Dose and Imaging
- Management of metastatic bone disease
- Prostate Cancer Treatment and Research
- Anatomy and Medical Technology
- Central Venous Catheters and Hemodialysis
- Renal and Vascular Pathologies
- Digital Imaging in Medicine
- Ferroptosis and cancer prognosis
- Food composition and properties
- Ovarian cancer diagnosis and treatment
- Crop Yield and Soil Fertility
- Lung Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
Christiana Care Health System
2019-2025
Indian Agricultural Research Institute
2023-2024
University of Pennsylvania
2013-2023
Philadelphia University
2023
Sidney Kimmel Cancer Center
2016-2020
Thomas Jefferson University
2015-2020
INHS Asvini
2020
ICARE Eye Hospital & Postgraduate Institute
2019-2020
Jaypee Institute of Information Technology
2015
University of Pittsburgh
2009-2011
Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple sites. However, such centralization challenging scale (or even not feasible) due various limitations. Federated ML (FL) provides an alternative train accurate generalizable models, only numerical model updates. Here we present findings the largest FL study...
Abstract Glioblastoma is the most common aggressive adult brain tumor. Numerous studies have reported results from either private institutional data or publicly available datasets. However, current public datasets are limited in terms of: a) number of subjects, b) lack consistent acquisition protocol, c) quality, d) accompanying clinical, demographic, and molecular information. Toward alleviating these limitations, we contribute “University Pennsylvania Imaging, Genomics, Radiomics”...
One of the biggest challenges to be addressed in world agriculture is low nitrogen (N) use efficiency (<40%). To address this issue, researchers have repeatedly underlined need for greater emphasis on development and promotion energy efficient, environmentally sound novel fertilizers, addition improved agronomic management augment nutrient restoring soil fertility increasing farm profit. Hence, a fixed plot field experiment was conducted assess economic environmental competency...
Background Imaging of glioblastoma patients after maximal safe resection and chemoradiation commonly demonstrates new enhancements that raise concerns about tumor progression. However, in 30% to 50% patients, these primarily represent the effects treatment, or pseudo‐progression (PsP). We hypothesize quantitative machine learning analysis clinically acquired multiparametric magnetic resonance imaging (mpMRI) can identify subvisual characteristics provide robust, noninvasive signatures...
Abstract The growing popularity of nano-fertilization around the world for enhancing yield and nutrient use efficiency has been realized, however its influence on soil microbial structure is not fully understood. purpose carrying out this study was to assess combined effect nano conventional fertilizers biological indicators crop in a wheat–maize system. results indicate that at par grain wheat maize obtained with application 75% recommended nitrogen (N) full dose phosphorus (P) potassium...
Brain extraction, or skull-stripping, is an essential pre-processing step in neuro-imaging that has a direct impact on the quality of all subsequent processing and analyses steps. It also key requirement multi-institutional collaborations to comply with privacy-preserving regulations. Existing automated methods, including Deep Learning (DL) based methods have obtained state-of-the-art results recent years, primarily targeted brain extraction without considering pathologically-affected...
The standard of care after resection a single brain metastasis is to treat the cavity with stereotactic radiation therapy (SRT) minimize risk recurrence. However, prospective randomized trial SRT demonstrated higher than expected rates local recurrence, possibly due geographic miss. Conformal partial (CPB) irradiation using conventional fractionation an alternate technique that allows larger margin healthy tissue be safely irradiated, potentially decreasing tumor We performed retrospective...
Purpose: Glioblastoma, the most common and aggressive adult brain tumor, is considered noncurative at diagnosis, with 14 to 16 months median survival following treatment. There increasing evidence that noninvasive integrative analysis of radiomic features can predict overall progression-free survival, using advanced multiparametric magnetic resonance imaging (Adv-mpMRI). If successfully applicable, such markers considerably influence patient management. However, patients prior initiation...
Oropharyngeal squamous cell cancers (OPSCCs) are traditionally managed with surgery and, if indicated, adjuvant radiation therapy (RT) or without chemotherapy. NCCN recommends keeping the time from to start of RT (TSRT) within 6 weeks avoid possibly compromising patient outcomes. HPV+ OPSCCs behave more favorably than HPV- OPSCCs. We hypothesized that TSRT beyond may not portend poorer outcomes for former.
Objective. We describe a case series constituting the first clinical trial by intravenous (IV) team nurses using sonic flashlight (SF) for ultrasound guidance of peripherally inserted central catheter (PICC) placement. Methods. Two IV with more than 10 years experience placing PICCs and 3 to 6 attempted place under in patients requiring long-term access. One two methods was used: conventional (CUS; 60 patients) or new device called SF (44 patients). The number needle punctures required gain...
We have developed a new image-based guidance system for microsurgery using optical coherence tomography (OCT), which presents virtual image in its correct location inside the scanned tissue. Applications include surgery of cornea, skin, and other surfaces below shallow targets may advantageously be displayed naked eye or low-power magnification by surgical microscope loupes (magnifying eyewear). OCT provides real-time highresolution (3 micron) images at video rates within two more millimeter...
The major challenge of growing soybean, other than unfavorable weather and small farm size, is the non-availability quality inputs at right time. Furthermore, in soybean regions, crop productivity soil environment have deteriorated due to use traditional varieties conventional methods production. Soybean intensification or system (SCI) an agricultural production that boosts yields, improves environment, maximizes efficiency input utilization, although contribution SCI not well understood as...
Background and Purpose: Real-time tomographic reflection is a novel technique that uses geometrically fixed arrangement of conventional ultrasound transducer, transducer-incorporated monitor, half-silvered mirror. This device, dubbed the Sonic Flashlight, generates virtual anatomically scaled image, obviating need for separate monitor. It may therefore facilitate invasive procedures, such as percutaneous access to kidney. proof-of-concept study assesses feasibility this renal imaging...
We sought to evaluate pathological response, tolerance, and outcome after preoperative (neoadjuvant) high dose rate brachytherapy in a small series of patients with clinical stage II endometrial carcinoma, fractionation protocol for this treatment.Twelve women diagnosed carcinoma from 1999-2010 were treated radiation therapy. Their medical charts retrospectively analyzed HDR treatment regimen, longitudinal outcomes. Radiation doses normalized biologically equivalent 2 Gy per fraction...