- Animal Virus Infections Studies
- Virology and Viral Diseases
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Bacteriophages and microbial interactions
- Viral Infections and Immunology Research
- Influenza Virus Research Studies
- Animal Nutrition and Physiology
- Antimicrobial Peptides and Activities
- Respiratory viral infections research
- Genetics, Aging, and Longevity in Model Organisms
- Helminth infection and control
- MicroRNA in disease regulation
- Microbial infections and disease research
- Molecular Biology Techniques and Applications
- Coccidia and coccidiosis research
- Viral Infections and Vectors
- vaccines and immunoinformatics approaches
- Probiotics and Fermented Foods
- Neurobiology and Insect Physiology Research
- Traditional Chinese Medicine Analysis
- Microplastics and Plastic Pollution
- Parasitic Infections and Diagnostics
- Vector-Borne Animal Diseases
Chongqing University of Technology
2022-2025
University of Toronto
2025
Henan Institute of Science and Technology
2013-2024
Xinxiang University
2019-2024
Hangzhou Dianzi University
2022-2024
Southeast University
2023
Yunnan University
2022
China National Petroleum Corporation (China)
2020
Southwest Medical University
2019
Air Force Medical University
2011
Artemisia argyi (AA) is promising as a potential feed additive. Microbial fermentation beneficial to the degradation of cell walls and better release bioactive compounds AA. However, there are few reports on application fermented AA additive for broilers. The present study intended evaluate value broilers by examining effects dietary supplementation Aspergillus niger-fermented unfermented growth performance, slaughter meat quality brokers. A total 360 newly hatched (1-day-old) with similar...
This article presents the generation of monoclonal antibodies (mAbs) with high specificity against 19-nortestosterone (NT) through cell fusion techniques and development a mAb-based indirect competitive ELISA (icELISA) method colloidal gold-based immuno-chromatographic assay to detect NT residues in beef pork samples. A modified carbodiimide was employed synthesize artificial antigen, BALB/c mice were used produce anti-NT mAbs. On basis checkerboard titration, an standard curve established....
Abstract Diabetes is now a global chronic disease, with the number of people diabetes expected to reach 643 million by end 2030. Semaglutide, human glucagon-like peptide-1 (GLP-1) analogue 94% similarity GLP-1, can promote insulin secretion and repress glucagon in glucose concentration-dependent manner, resulting substantial improvement blood levels reducing risk hypoglycemia patients type 2 diabetes. To improve absorption efficiency semaglutide oral delivery, we developed chitosan...
The Rab family of small guanosine triphosphatases (GTPases) are nucleotide-dependent switches. Mutations in Rabs can result human diseases. Rab7a and Rab7b transition from early endosomes to lysosomes presumed function similarly. Most studies look at Rab7a, less on Rab7b, with the underlying assumption they There have yet be articles comparing them side by side. Whilst cloning Rab7 homologues, we identified splice isoforms for only. These isoforms, Rab7b2 Rab7bx8 lacking different exons, not...
In recent years, as an emerging pollutant, microplastic (MPs) pollution is gradually becoming a research hotspot. MPs are ubiquitous in the entire ecological environment. Organisms can be exposed to via inhalation or ingestion. view of widespread pollution, impact on biology should further investigated. previous experiments, we have conducted physiology Drosophila polyethylene terephthalate microplastics (PET-MPs). However, will lifespan affected under long-term PET-MPs exposure? The...
Lung cancer is a leading cause of mortality worldwide, with 5-year survival rate less than 20%. Gambogic acid (GA) naturally occurring and potent anticancer agent that destroys tumor cells through multiple mechanisms. According to the literature, one most inhibitors caspases apoptosis currently known X-linked Inhibitor Apoptosis Protein (XIAP). It highly expressed in various malignancies but has little or no expression normal cells, making it an attractive target for treatment. Here we...
Infectious bursal disease virus (IBDV) is still a vital etiological agent in poultry farms. IBDV outbreaks occasionally occur due to the presence of very virulent, reassortment or variant strains. Vaccine immunization has played crucial roles IBD control for decades. However, survival pressure from vaccine also increases reassortments circulating viruses. In this study, an strain was isolated several broiler farms Henan Province, central part China, and named HN strain. Based on results...
African swine fever (ASF) is a highly contagious disease caused by virus (ASFV), affecting domestic and wild boars. The polyprotein pp220 of ASFV responsible for producing the major structural proteins p150, p37, p14, p34, p5 via proteolytic processing. p34 protein main component core shell. However, immunologic properties in vitro vivo remain unclear. results showed that recombinant expressed prokaryotes eukaryotes could react with convalescent sera to ASFV, suggesting an immunogenic...
Infectious bursal disease virus (IBDV) infection causes immunosuppression in chickens and increases their susceptibility to secondary infections. To explore the interaction between host IBDV, RNA-Seq was applied analyse transcriptional profiles of responses chickens' bursas Fabricius early stage IBDV infection. The results displayed that a total 15546 genes were identified chicken bursa libraries. Among annotated genes, there 2006 4668 differentially expressed group compared with mock on day...
So far, the pathogenesis of demyelination caused by canine distemper virus (CDV) in central nervous system has remained unclear, although a lot studies have been done extensively. To further investigate relation variety cells brain to demyelination, this study was performed on 15 dogs with spontaneous acute and 2 controls. According anatomical relation, divided into cerebrum, cerebral stem cerebellum. The sections no, mild, moderate, or severe demyelinating lesions were selected respectively...
Abstract Porcine Epidemic Diarrhea Virus (PEDV) poses a significant threat to neonatal piglets, particularly due the limited efficacy of existing vaccines and scarcity efficacious therapeutic drugs. Gegen Qinlian Decoction (GQD) has been employed for over two millennia in treating infectious diarrhea. Nonetheless, further scrutiny is required improve drug’s elucidate its underlying mechanisms action. In this study, modified GQD (MGQD) was developed demonstrated capacity inhibit replication...
The post-00s college students are a group of “internet natives” with distinctive personality and innovative spirit. It is important to explore how motivate them actively learn new knowledge. Debate, as means learning communication, can enhance participants’ critical thinking skills, boost oral promote their relevant Here, we use the model classroom debate in general education biology course scientific controversies. This increases students’ enthusiasm for independent knowledge promotes...
Infectious bursa disease virus (IBDV) pathogenesis is characterized by increased numbers of T cells and decreased B in the bursa. Currently, little about key factor that affects migration into In humans, CC chemokine ligand 19 (CCL19) recruits monocytes neutrophils usually involved various inflammatory disorders. The aim this study was to assess roles CCL19 driving peripheral blood infiltration Fabricius chickens infected with IBDV. Bursal samples were collected from infection group control...
Broiler ascites syndrome (AS), is a nutritional and metabolic disease that occurs in fast-growing commercial broiler chickens. AS can cause poor growth significant increase the rate of deaths, which has resulted serious economic losses to poultry industry. The classic traditional Chinese medicine Qiling Jiaogulan Powder (QLJP) been demonstrated have certain therapeutic effect on AS. However, its pharmacological mechanism remains be elucidated. This study was performed investigate multitarget...