Leonardo dos Santos Lourenço Bastos

ORCID: 0000-0001-7833-0403
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Research Areas
  • COVID-19 epidemiological studies
  • COVID-19 Clinical Research Studies
  • Sepsis Diagnosis and Treatment
  • COVID-19 and healthcare impacts
  • Health Systems, Economic Evaluations, Quality of Life
  • Healthcare Policy and Management
  • Intensive Care Unit Cognitive Disorders
  • Hemodynamic Monitoring and Therapy
  • Mosquito-borne diseases and control
  • Vaccine Coverage and Hesitancy
  • Climate Change and Health Impacts
  • Respiratory Support and Mechanisms
  • Healthcare Systems and Reforms
  • Rural Development and Agriculture
  • SARS-CoV-2 and COVID-19 Research
  • Machine Learning in Healthcare
  • Sustainable Supply Chain Management
  • COVID-19 and Mental Health
  • Healthcare Operations and Scheduling Optimization
  • Intracranial Aneurysms: Treatment and Complications
  • Malaria Research and Control
  • Disaster Response and Management
  • Acute Ischemic Stroke Management
  • Cardiac Arrest and Resuscitation
  • Education during COVID-19 pandemic

Pontifical Catholic University of Rio de Janeiro
2017-2025

D’Or Institute for Research and Education
2021

Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde
2021

Universidade do Estado do Pará
2016

OBJECTIVE: To estimate the reporting rates of coronavirus disease 2019 (COVID-19) cases for Brazil as a whole and states. METHODS: We estimated actual number COVID-19 using reported deaths in each state, expected case-fatality ratio from World Health Organization. Brazil's was also adjusted by population's age pyramid. Therefore, notification rate can be defined confirmed (notified Ministry Health) divided (estimated deaths). RESULTS: The at 9.2% (95%CI 8.8% - 9.5%), with all states...

10.5935/0103-507x.20200030 article EN cc-by-nc Revista Brasileira de Terapia Intensiva 2020-01-01

Clinical characteristics and management of COVID-19 patients have evolved during the pandemic, potentially changing their outcomes. We analyzed associations changes in mortality rates with clinical profiles respiratory support strategies critically ill patients. A multicenter cohort RT-PCR-confirmed admitted at 126 Brazilian intensive care units between February 27th October 28th, 2020. Assessing temporal deaths, we identified distinct time periods. evaluated association 60-day in-hospital...

10.1007/s00134-021-06388-0 article EN other-oa Intensive Care Medicine 2021-04-14

Objective: Outcomes of low-risk patients may be affected by the overall acuity ICU to which they were admitted. Studies addressing this topic are very scarce and underlying mechanisms supporting association remain incompletely understood. Here, we investigated effects (defined as mean Simplified Acute Physiology Score 3 all admitted in bimester a given patient was admitted) organizational factors on outcomes with low risk dying ICUs. Design: Retrospective cohort study. Setting: One hundred...

10.1097/ccm.0000000000006592 article EN Critical Care Medicine 2025-02-07

To analyse the measures adopted by countries that have shown control over transmission of coronavirus disease 2019 (COVID-19) and how each curve accumulated cases behaved after implementation those measures.The methodology for this study comprises three phases: systemizing different countries, identifying structural breaks in growth number analyzing Brazilian data particular.We noted China (excluding Hubei Province), Province, South Korea been effective their deceleration rates COVID-19...

10.5935/0103-507x.20200028 article EN cc-by-nc Revista Brasileira de Terapia Intensiva 2020-01-01

There is limited information on the inequity of access to vaccination in low-and-middle-income countries during COVID-19 pandemic. Here, we described progression Brazilian immunisation program for COVID-19, and association socioeconomic development with rates, considering potential protective effect primary health care coverage.

10.1016/j.lana.2022.100335 article EN cc-by-nc-nd The Lancet Regional Health - Americas 2022-08-17

The COVID-19 pandemic tested the capacity of intensive care units (ICU) to respond a crisis and demonstrated their fragility. Unsurprisingly, higher than usual mortality rates, lengths stay (LOS), ICU-acquired complications occurred during pandemic. However, worse outcomes were not universal nor constant across ICUs significant variation in was reported, demonstrating that some could adequately manage surge COVID-19. In present editorial, we discuss concept resilient Intensive Care Unit,...

10.1186/s13613-022-01011-x article EN cc-by Annals of Intensive Care 2022-04-26

To evaluate risk factors, molecular profiles, and hospital mortality of carbapenem-resistant Enterobacterales (CRE) infections in intensive care unit patients. In this retrospective, multicenter cohort study, admissions from 52 units between January 2019 December 2020 were analyzed a nested case-control design. Patients with propensity score-matched 1:1 to those carbapenem-susceptible infections. Hierarchical conditional logistic regression identified factors for Enterobacterales,...

10.62675/2965-2774.20250237 article EN Critical Care Science 2025-01-01

Background Tests are scarce resources, especially in low and middle-income countries, the optimization of testing programs during a pandemic is critical for effectiveness disease control. Hence, we aim to use combination symptoms build predictive model as screening tool identify people areas with higher risk SARS-CoV-2 infection be prioritized testing. Materials methods We performed retrospective analysis individuals registered " Dados do Bem ," Brazilian app-based symptom tracker. applied...

10.1371/journal.pone.0248920 article EN cc-by PLoS ONE 2021-03-25

Long COVID is an emerging global public health issue. Socially vulnerable communities in low- and-middle-income countries were severely impacted by the pandemic and are underrepresented research. This prospective study aimed to determine prevalence of long COVID, its impact on health, associated risk factors one such community Rio de Janeiro, Brazil.

10.1016/j.lana.2024.100839 article EN cc-by-nc-nd The Lancet Regional Health - Americas 2024-07-17

Background: Artificial Intelligence has been an area of great interest and investment in the industrial sector, offering numerous possibilities to enhance efficiency accuracy production processes. In this regard, study aimed identify adoption challenges determine which these apply context emerging economy, considering aspects Industry 4.0. Methods: To achieve objective, a literature review was conducted, survey carried out among professionals field operating within Brazilian context. The...

10.3390/eng4030133 article EN cc-by Eng—Advances in Engineering 2023-09-12

Among all existing inventory replenishment models, this research was dedicated to the Joint Replenishment Problem (JRP), which consists in of multiple items simultaneously, aiming total cost reduction. Literature has presented several optimal and approximated solutions problem, with different applications techniques, results a large quantity solution proposals. Therefore, aimed map problem 2006-2015 order provide guide for interested parts JRP update previous reviews. Hence, systematic...

10.1590/0103-6513.222916 article EN Production 2017-01-01

Background The integration of digital health (eHealth) interventions into primary healthcare systems has gained recognition lately in Low- and Middle-Income Countries (LMICs) to enhance quality, accessibility, efficiency. These may offer effective strategies mitigating the burden chronic diseases by facilitating access remote optimising its processes. This scoping review aims identify assess eHealth implemented care settings LMICs for further development adaptation. Methods analysis We will...

10.29392/001c.120508 article EN cc-by Journal of Global Health Reports 2024-07-01

Background: Convalescent plasma is a potential therapeutic option for critically ill patients with coronavirus disease 19 (COVID-19), yet its efficacy remains to be determined. The aim was investigate the effects of convalescent (CP) in COVID-19. Methods: This single-center prospective observational study conducted Rio de Janeiro, Brazil, from March 17th May 30th, final follow-up on June 30th. We included 113 laboratory-confirmed COVID-19 respiratory failure. Primary outcomes were time...

10.3389/fmed.2021.630982 article EN cc-by Frontiers in Medicine 2021-01-28
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