- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Pituitary Gland Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological disorders and treatments
- Neurological Complications and Syndromes
- Infectious Encephalopathies and Encephalitis
- Intracranial Aneurysms: Treatment and Complications
- Venous Thromboembolism Diagnosis and Management
- Neurological and metabolic disorders
- Vascular Malformations Diagnosis and Treatment
- Anatomy and Medical Technology
- Temporomandibular Joint Disorders
- Periodontal Regeneration and Treatments
- Obsessive-Compulsive Spectrum Disorders
- Neurosurgical Procedures and Complications
- Advanced Neuroimaging Techniques and Applications
- Polyomavirus and related diseases
- Genetic Neurodegenerative Diseases
- Adrenal Hormones and Disorders
- Botulinum Toxin and Related Neurological Disorders
- Systemic Lupus Erythematosus Research
- Medical Imaging and Pathology Studies
- Blood Coagulation and Thrombosis Mechanisms
University of Lisbon
2015-2025
Centro Hospitalar Lisboa Norte
2012-2025
Hospital de Santa Maria
2012-2024
Hospital CUF Descobertas
2023-2024
Hospital do Desterro
2023-2024
Universidade Nova de Lisboa
2024
New York Proton Center
2020
American Headache Society
2020
Iscte – Instituto Universitário de Lisboa
2019
Universidad de Extremadura
2017
The influence of burnout, academic engagement, and their interaction in dropout intention among medical students should be further studied. Current research shows its consequences are relevant, however, there is little understanding on burnout engagement moderation intention. current study tested a model that relates the effects coping strategies, social support satisfaction, general distress intention, students.Through an online survey non-probabilistic sample one Medical Faculty's 1st-...
Background and Purpose— The hypothesis that venous recanalization prevents progression of infarction is not established in patients with cerebral thrombosis (CVT). Evidence also scarce on the association between residual symptoms, particularly headache, grade. We aimed to assess, CVT treated standard anticoagulation, (1) rate early recanalization, (2) whether lack was predictor parenchymal brain lesion progression, (3) prevalence features persistent headache according grade achieved....
Background The effect of different anticoagulants on recanalization after cerebral venous thrombosis has not been studied in a randomized controlled trial. Methods RE-SPECT CVT (ClinicalTrials.gov number: NCT02913326) was Phase III, prospective, randomized, parallel-group, open-label, multicenter, exploratory trial with blinded endpoint adjudication. Acute patients were allocated to dabigatran 150 mg twice daily, or dose-adjusted warfarin, for 24 weeks, 5–15 days’ treatment unfractionated...
There are significant discrepancies in the optic nerve sheath diameter (ONSD) reported literature. We aimed to determine ultrasonographic imaging features of ONSD and ophthalmic vessels a healthy population, using standardized protocol, estimate effect demographics positioning changes on measurements. measured mean values supine sitting position Doppler parameters ophthalmic, central retinal short posterior ciliary arteries. Inter-observer reliability was assessed intraclass correlation...
Experimental studies suggest inflammation can contribute to blood barrier disruption and brain injury in cerebral venous thrombosis (CVT). We aimed determine whether biomarkers of were associated with the evolution lesions, persistent occlusion or functional outcome patients CVT.Pathophysiology Venous Infarction-Prediction Infarction Recanalization CVT (PRIORITy-CVT) was a multicenter prospective cohort study newly diagnosed CVT. Evaluation neutrophil-to-lymphocyte ratio (NLR) C-reactive...
Introduction Current guidelines recommend that patients with cerebral venous thrombosis (CVT) should be treated vitamin K antagonists (VKAs) for 3–12 months. Direct oral anticoagulants (DOACs), however, are increasingly used in clinical practice. An exploratory randomized controlled trial including 120 CVT suggested the efficacy and safety profile of dabigatran (a DOAC) is similar to VKAs treatment CVT, but large-scale prospective studies from a real-world setting lacking. Methods DOAC-CVT...
Background and Purpose— The brush sign (BS) is an abnormally accentuated signal drop of the subependymal deep medullary veins in paramagnetic-sensitive magnetic resonance sequences, previously described acute ischemic stroke. We aimed to describe BS patients with thrombosis cerebral sinuses explore its association clinical severity, extent, parenchymal brain lesion, prognosis. Methods— assessed consecutive adult admitted 2 university hospitals diagnosis imaging assessment imaging, including...
Background Discrepancies in the literature regarding optimal optic nerve sheath diameter (ONSD) cutoffs for intracranial pressure (ICP) necessitate alternative neuroimaging parameters to improve clinical management. Purpose To evaluate diagnostic accuracy of dimensions perineural subarachnoid space ratio, measured using US, predicting increased ICP. Materials and Methods In a prospective cohort study from April 2022 December 2023, patients with suspected ICP underwent US determine arachnoid...
Background Headache in ischemic stroke survivors after the acute stage is incompletely described. Objective We aimed to prospectively describe characteristics of headache and predictors at chronic stroke. Methods conducted a prospective observational cohort study including 102 patients admitted Stroke Unit. Patients were interviewed (12 months stroke). Characteristics those headaches collected using previously validated questionnaire enabling classification following International Society...
Abstract Background Elucidating mechanisms of brain damage in cerebral venous thrombosis (CVT) would be instrumental to develop targeted therapies and improve prognosis prediction. Matrix metalloproteinase-9 (MMP-9), a gelatinase that degrades major components the basal lamina, has been associated blood–brain barrier disruption. We aimed assess, patients with CVT, temporal change serum concentrations MMP-9 its association key imaging clinical outcomes. Methods Pathophysiology Venous...
Introduction: There is limited evidence regarding long-term outcomes of aneurysmal subarachnoid hemorrhage survivors. Most follow-up programs are relatively short and focused on physical functions. Endovascular embolization enables recovery normal vascular architecture. However, there growing that neuropsychological behavior sequelae can significantly impact the lives these patients, even when treatment successful. In this study, we reviewed cognition, psychiatric symptoms, global...