A5101908749- Bioinformatics and Genomic Networks
- Genetic Associations and Epidemiology
- Gene expression and cancer classification
- Systemic Lupus Erythematosus Research
- Advanced Authentication Protocols Security
- Cryptography and Data Security
- User Authentication and Security Systems
- Parkinson's Disease Mechanisms and Treatments
- Cytokine Signaling Pathways and Interactions
- Rheumatoid Arthritis Research and Therapies
- RNA modifications and cancer
- Genetic Mapping and Diversity in Plants and Animals
- Child Nutrition and Water Access
- Machine Learning in Bioinformatics
- Advanced Image and Video Retrieval Techniques
- Chronic Lymphocytic Leukemia Research
- Epigenetics and DNA Methylation
- Nutrition, Genetics, and Disease
- vaccines and immunoinformatics approaches
- Image Retrieval and Classification Techniques
- Advanced Malware Detection Techniques
- Biomedical Text Mining and Ontologies
- Computational Drug Discovery Methods
- Metabolomics and Mass Spectrometry Studies
- Cancer-related gene regulation
Shaanxi University of Science and Technology
2022-2025
China Agricultural University
2025
Obstetrics and Gynecology Hospital of Fudan University
2024-2025
Qilu Normal University
2025
Harbin Medical University
2014-2024
Ningbo No. 2 Hospital
2022-2024
University of Chinese Academy of Sciences
2022-2024
Northwestern Polytechnical University
2009-2024
Huazhong University of Science and Technology
2018-2024
Tongji Hospital
2018-2024
<h3>Background and Objectives</h3> To estimate the rates of incidence, death, disability-adjusted life years (DALYs) ischemic stroke in young adults aged 15–49 relevant risk factors by sex, age group, sociodemographic index (SDI) 204 countries territories. <h3>Methods</h3> Data from Global Burden Diseases, Injuries, Risk Factors (GBD) 2019 study were used. The estimated annual percentage changes (EAPCs) calculated to evaluate temporal trends 1990 2019. We also contributing DALYs resulting...
The fruit of mulberry (Morus alba L., Moraceae) has been used as medicinal food in China for a long history. pigment from the extract is kind natural colourant processing and potential medical commercial values. This study focuses on analysis characterisation anthocyanins pigment. fresh fruits were extracted with solvent 95% alcohol/0.1% HC l (1:1, ratio) at room temperature 4 h dark. After isolation using C-18 column, was identified UV-Visible Spectroscopy, HPLC-PAD, LC-MS, 1HNMR. results...
Abstract Background IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, which a significant cause renal failure. At present, classification IgAN often limited to pathology, and its molecular mechanism has not been established. Therefore we aim identify subtypes at level explore heterogeneity in terms immune cell infiltration, functional level. Methods Two microarray datasets (GSE116626 GSE115857) were downloaded from GEO. Differential expression genes (DEGs) for...
Internet of Things provides complicated value-added services to mobile intelligent terminal users. Different sensors collect various data from the users and transmit for storage. Consequently, a great amount personal sensitive information related these rich colorful applications is stored in terminal. Mobile terminals have become prominent target network attackers. Security breach privacy leakage severely thread application development Things. We present privacy-preserving implicit...
ABSTRACT Background Sleep behaviors, defined by the total duration of sleep and chronotype, significantly influence overall health. Compromised quality, which is often manifested through reduced prevalence insomnia, has been found to be associated with micronutrient deficiencies. Nonetheless, existence a causal relationship between levels behaviors remains established. Methods A two‐sample Mendelian randomization (MR) analysis, utilizing data from genome‐wide association studies (GWAS), was...
Background: The molecular mechanisms of rheumatoid arthritis (RA) have not been fully elucidated. Housekeeping genes are often considered to be stably expressed in any tissue, cell, or disease state, and the relationship between housekeeping RA has never systematically analyzed. Results: Therefore, by collecting analyzing 140 gene expression profiling data, this study aimed explore whether abnormal RA. Fifteen datasets were included based on set inclusion exclusion criteria. By cumulative...
Head and neck squamous cell carcinoma (HNSCC) is the most common head cancer highly aggressive heterogeneous. Targeted therapy still main treatment method used in clinic due to lower side effect personalized medication. In order discover novel effective drugs with low against HNSCC, we analyzed genes related found that PIK3CA was expressed tumor tissues often experienced mutations, leading excessive activation of phosphoinositide 3-kinase alpha (PI3Kα), promoting development HNSCC. The...
Mechanical overloading can lead to disc degeneration. Nucleus pulposus (NP) cell senescence is aggravated within the degenerated disc. This study was designed investigate effects of high compression on NP and underlying molecular mechanism this process. Rat cells seeded in decalcified bone matrix were subjected non-compression (control) or (2% 20% deformation, 1.0 Hz, 6 hours/day). The reactive oxygen species (ROS) scavenger N-acetylcysteine (NAC) p38 MAPK inhibitor SB203580 used roles ROS...
Background: Both genetic and environmental factors contribute to the development of periodontitis. Genetic studies identified a variety candidate genes for The aim present study is identify most promising periodontitis using an integrative gene ranking method. Methods: Seed that were confirmed be associated with text mining. Three types then extracted from different resources (expression profiles, genome‐wide association studies). Combining seed genes, four freely available bioinformatics...
Acute myeloid leukemia (AML) is a cancer of the line blood cells, and generally considered to be caused by environment genetic factors. In this study, we combined genome-wide haplotype association study (GWHAS) gene prioritization strategy mine AML-related affect factors understand its pathogenesis. A total 175 AML patients were downloaded from public GEO database (GSE32462) 218 matched Caucasian controls HapMap Project. We first identified linkage disequilibrium (LD) blocks performed GWHAS...
Alzheimer's disease (AD) is an acquired disorder of cognitive and behavioral impairment. It considered to be caused by variety factors, such as age, environment genetic factors. In order identify the affect factors AD, we carried out a bioinformatic approach which combined genome-wide haplotype-based association study with gene prioritization. The raw SNP genotypes data was downloaded from GEO database (GSE33528). contains 615 AD patients 560 controls Caribbean Hispanic individuals. Firstly,...
Social engineering attacks are becoming serious threats to cloud service. attackers could get Cloud service custom privacy information or attack virtual machine images directly. Existing security analysis instruments difficult quantify the social risk, resulting in invalid defense guidance for attacks. In this article, a risk framework is proposed based on user profiling. The provides pathway quantitatively calculate possibility of being compromised by and potential loss, so as effectively...