- Bone health and osteoporosis research
- Obesity, Physical Activity, Diet
- Vitamin D Research Studies
- Nutritional Studies and Diet
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Nutrition, Health and Food Behavior
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Eating Disorders and Behaviors
- Physical Activity and Health
- Regulation of Appetite and Obesity
- Bone Metabolism and Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Bone health and treatments
- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Body Contouring and Surgery
- Health, Environment, Cognitive Aging
- Bone and Joint Diseases
- Toxic Organic Pollutants Impact
- Pressure Ulcer Prevention and Management
- Diet, Metabolism, and Disease
- Peripheral Nerve Disorders
Mie University
1995-2024
Koshien University
2012-2017
Takara (Japan)
2015-2017
National Center of Neurology and Psychiatry
2015
National Institute of Infectious Diseases
2007-2015
National Institute of Mental Health
2015
Kindai University
1998-2014
Osaka Medical and Pharmaceutical University
2014
Kindai University Hospital
2014
Tokyo Women's Medical University
2014
Understanding the influence of both genetics and environment on human health, especially early in life, is essential for shaping long-term health. Here, we utilize a nationwide prospective birth cohort, Japan Environment Children's Study (JECS), to conduct large-scale population-based genetic study using biannual questionnaire surveys biological physical measurements collected from parents their children since participant mothers were pregnant. Analyses genome-wide genotyping 80,638 child...
Background: Diabetes is an important risk factor for cardiovascular disease, certain types of cancer, and death, self-reports are one the most convenient methods ascertaining diabetes status. We evaluated validity among Japanese who participated in a health checkup.Methods: Self-reported was cross-sectionally compared with confirmed 2535 participants aged 28 to 85 years Saku cohort study. Confirmed defined as presence at least 1 following: fasting plasma glucose (FPG) level 126 mg/dL or...
Anemia continues to be a major public health problem significant among women of reproductive age (WRA) in developing countries, including Lao People's Democratic Republic (Lao PDR), where the prevalence anemia remains high. This study aimed assess and its associated factors WRA 15-49 years PDR. We conducted cross-sectional study, using Social Indicator Survey II, 2017 dataset. A total 12,519 tested for were included this through multistage sampling approaches. Binary logistic regression was...
Abstract Background Sex hormone-binding globulin (SHBG) levels and sex hormones have been implicated in the pathogenesis of type 2 diabetes cardiovascular diseases. As fatty liver has suggested to be a major determinant SHBG levels, we examined whether associations testosterone with were independent liver. Methods We conducted case–control study that included 300 cases (215 men 85 women) matched controls from Saku cohort study. Diabetes was defined by either fasting plasma glucose ≥126...
To evaluate the association between adiponectin complexes (high-molecular-weight [HMW], middle-molecular-weight [MMW], and low-molecular-weight [LMW] adiponectin) diabetes.We conducted a case-control study, based on cohort in Saku, Japan. Among 2565 participants, 300 participants with diabetes matched controls (430 men 170 women) were analyzed.After adjusting for age, physical activity, hypertension, family history, alcohol use, smoking, menopausal status, total, HMW, LMW, but not MMW levels...
The prevalence of diabetes is increasing globally. In addition to established risk factors for diabetes, such as diet, inactivity, overweight and obesity, the involvement persistent organic pollutants, including dioxins polychlorinated biphenyls (PCBs), has also been suggested be a possible, but controversial, cause this epidemic. present study investigated association between blood PCB congener levels among middle-aged, obese Japanese participants in Saku Control Obesity Program. One...
Anemia is a major public health concern among children aged <5 years in the Lao People’s Democratic Republic. Thus far, no study has determined factors associated with anemia Republic using nationwide representative sample. Therefore, this aimed to evaluate prevalence of and its multilevel variations 6–59 months. This quantitative, cross-sectional used nationally sample from Social Indicator Survey II, 2017. Children months tested for were included through multistage sampling approaches....
Several cross-sectional studies in Pima Indians and Caucasians have indicated that obese individuals with type 2 diabetes a higher basal metabolic rate (BMR) than healthy, individuals. However, no study has investigated this comparison Japanese subjects, who are known to be susceptible due genetic characteristics. Thirty adults pre-type (n=7) or (n=13) without (n=10) participated study. BMR was measured using indirect calorimetry. The relationships between residual (calculated as minus...
Objectives One of the diversity indicators food intake in elderly Japanese population is Dietary Variety Score (DVS). Studies on people have reported relationship with health outcomes, such as body function, higher-level functional capacity, fall risk, and sarcopenia. However, index not been studied enough whether it suggestive nutrients characteristics meal by various intakes. The purpose this study was to clarify DVS its nutrient intakes days consisting staple foods, main dishes, side...
Vitamin D receptor (VDR) gene polymorphisms have been inconsistently associated with bone mineral density (BMD). To precisely evaluate the associations between three VDR and BMD, we performed a large-scale representative study of Japanese female population.Fifty women were randomly selected from each 5-year age stratified populations (15-79 years) in municipalities examined, as part population-based osteoporosis (JPOS) baseline 1996. In study, BMD at lumbar spine, hip, distal forearm...
The objective of the present study was to investigate relationship between indices body size such as BMI, fat-free mass index (FFMI, FFM/height 2 ), fat (FMI, FM/height and percentage (%BF), physical activities assessed by doubly-labelled water (DLW) method an accelerometer in free-living Japanese adult women. We conducted a cross-sectional 100 female subjects ranging age from 31 69 years. Subjects were classified quartiles FFMI, FMI %BF. Daily walking steps duration light vigorous activity...
The purpose of the present study was to determine whether depression associated with metabolic syndrome and unhealthy behaviours in community residents.Using 2009-2010 baseline data Saku Cohort Study, 1,225 men women who participated a health screening were included cross-sectional analyses. Depression assessed using Zung Self-Rating Scale. Consistent Japanese Society Internal Medicine's definition, we defined as abdominal obesity plus two or more following: high blood pressure,...
The objective of the present study was to investigate whether a previously reported apparent negative relationship between fat mass and daily physical activity in Japanese adult women would also be observed men. subjects were grouped into quartiles BMI body percentage (%BF). number steps walked each day duration light- vigorous-intensity assessed by an accelerometer over same period time as for doubly labelled water experiment. results showed that negatively correlated with spent...
Purpose. To examine behavioral factors related to successful weight maintenance. Methods. Subjects were 90 middle-aged participants who attended a loss program and followed for one year. The subjects classified into either maintainers (maintained of 5% or more from their initial year) (SWM) unsuccessful (USWM), control practice, stress, obstacles, support, self-efficacy during the follow-up period compared. Results. SWM had mean 12% program. They showed greater improvement in regularity...
The Japanese Population-based Osteoporosis (JPOS) Cohort Study was launched in 1996 to produce a reference database of areal bone mineral density (aBMD) by dual energy X-ray absorptiometry (DXA) and turnover markers the female population determine risk factors for osteoporotic fractures. At baseline, 3984 women aged 15 79 years were randomly selected provide representative status data aBMD values diagnosis osteoporosis. Follow-up surveys conducted 1999, 2002, 2006 2011/12 changes identify...