A5073535265- Reproductive Biology and Fertility
- Advanced MRI Techniques and Applications
- Sperm and Testicular Function
- Prenatal Screening and Diagnostics
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Electrical and Bioimpedance Tomography
- Advanced Neuroimaging Techniques and Applications
- Microwave Imaging and Scattering Analysis
- Atomic and Subatomic Physics Research
- Cystic Fibrosis Research Advances
- Ultrasound and Hyperthermia Applications
- Functional Brain Connectivity Studies
- MRI in cancer diagnosis
- Sexual function and dysfunction studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Multiple Sclerosis Research Studies
- Medical Imaging Techniques and Applications
- Ovarian function and disorders
- Renal and related cancers
- Cardiac Imaging and Diagnostics
- Genomic variations and chromosomal abnormalities
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Reproductive System and Pregnancy
Advanced Imaging Research (United States)
2023-2025
The University of Texas Southwestern Medical Center
2023-2025
National Institute of Neurological Disorders and Stroke
2017-2024
National Institutes of Health
2017-2024
Southwestern Medical Center
2023
Hubei University of Technology
2022-2023
National Taiwan University of Science and Technology
2021
Peking University
2020
Peking University Cancer Hospital
2020
University of Minnesota
2011-2018
Previously reported better fertilization rate after intracytoplasmic single sperm injection (ICSI) than subzonal insemination of several spermatozoa was confirmed in a controlled comparison the two procedures 11 patients. Intracytoplasmic carried out 150 consecutive treatment cycles infertile couples, who had failed to have fertilized oocytes standard in-vitro (IVF) or were not accepted for IVF because enough motile present ejaculate. A spermatozoon injected into ooplasm 1409 metaphase II...
Single embryo transfer (SET) remains underutilized as a strategy to reduce multiple gestation risk in IVF, and its overall lower pregnancy rate underscores the need for improved techniques select one fresh transfer. This study explored use of comprehensive chromosomal screening by array CGH (aCGH) provide this advantage improve from SET.First-time IVF patients with good prognosis (age <35, no prior miscarriage) normal karyotype seeking elective SET were prospectively randomized into two...
Journal Article Higher success rate by intracytoplasmic sperm injection than subzonal insemination. Report of a second series 300 consecutive treatment cycles Get access André C. Van Steirteghem, Steirteghem 1 1To whom correspondence should be addressed Search for other works this author on: Oxford Academic PubMed Google Scholar Jiaen Liu, Liu Hubert Joris, Joris Zsolt Nagy, Nagy Cécile Janssenswillen, Janssenswillen Herman Tournaye, Tournaye Marie-Paule Derde, Derde 2Biostatistics...
Intracytoplasmic sperm injection (ICSI) has been successful in cases of extreme oligoasthenozoospermia achieving pregnancies via in-vitro fertilization (IVF) with the lowest imaginable counts. In azoospermia caused by congenital bilateral absence vas deferens (CBAVD), it shown that epididymal spermatozoa can be retrieved large numbers, but rates using conventional IVF are low. Furthermore, no ever possible testicular IVF. most case epididymis, only from macerated biopsy specimens. such...
From October 1992 to December 1994, 2732 cycles of treatment by intracytoplasmic sperm injection (ICSI) were carried out in couples mainly with severe male-factor infertility. The overall fertilization rate these was 71% intact oocytes. However, 76 (72 couples) cycles, none the injected oocytes became fertilized,so total failure 3% (76/2732 cycles). Details analysed. results show that after ICSI may be explained different factors related (i) semen characteristics (only immotile or...
Recent advances in time-lapse monitoring IVF treatment have provided new morphokinetic markers for embryonic competence. However, there is still very limited information about the relationship between parameters, chromosomal compositions and implantation potential. Accordingly, this study aimed at investigating effects of selecting competent blastocysts transfer by combining array CGH testing on pregnancy outcomes patients undergoing preimplantation genetic screening (PGS).A total 1163...
Journal Article Andrology: Successful fertilization and establishment of pregnancies after intracytoplasmic sperm injection in patients with globozoospermia Get access Jiaen Liu, Liu 1 Centre for Reproductive Medicine, University Hospital, Dutch-speaking Brussels Free (Vrije Universiteit Brussel)Laarbeeklaan 101, B-1090 Brussels, Belgium 1To whom correspondence should be addressed Search other works by this author on: Oxford Academic PubMed Google Scholar Zsolt Nagy, Nagy Hubert Joris, Joris...
In seven patients who did not become pregnant following microsurgical epididymal sperm aspiration (MESA) and intracytoplasmic injection (ICSI), a subsequent ICSI was performed using previously cryopreserved supernumerary spermatozoa without re-operating on the husband. During original MESA procedure mean concentration of 12.3×106/ml achieved. The were for later use. After thawing frozen 1.9×106 spermatozoa/ml obtained in straws containing total volume suspension 250 μl. From 68 intact...
Purpose To develop high‐resolution electrical properties tomography (EPT) methods and investigate a gradient‐based EPT (gEPT) approach that aims to reconstruct the (EP), including conductivity permittivity, of an imaged sample from experimentally measured B 1 maps with improved boundary reconstruction robustness against measurement noise. Theory Methods Using multichannel transmit/receive stripline head coil acquired for each element, by assuming negligible z component compared transverse...
Elevated specific absorption rate (SAR) associated with increased main magnetic field strength remains a major safety concern in ultra-high-field (UHF) resonance imaging (MRI) applications. The calculation of local SAR requires the knowledge electric induced by radio-frequency (RF) excitation, and electrical properties tissues. Since distribution cannot be directly mapped conventional MR measurements, estimation is usually performed using numerical model-based electromagnetic simulations...
The purpose is to provide a comprehensive review of the electrical properties tomography (EPT) technique, which was introduced image (EPs) tissue noninvasively by exploiting measured field data MRI.
Recent advances in next-generation sequencing (NGS) have provided new methods for preimplantation genetic screening (PGS) of human embryos from vitro fertilization (IVF) cycles. However, there is still limited information about clinical applications NGS IVF and PGS (IVF-PGS) treatments. The present study aimed to investigate the effects on pregnancy implantation outcomes patients comparison array comparative genomic hybridization (aCGH) screening.This was performed two phases. Phase I...
Men with congenital bilateral absence of the vas deferens (CBAVD) have been regarded as presenting a mild form cystic fibrosis (CF). In this article, we report case male-factor infertility, in which both partners are carriers delta F508 mutation and male partner has CBAVD. Microsurgical epididymal sperm aspiration (MESA) was performed to obtain spermatozoa; intracytoplasmic injection (ICSI) carried out on oocytes since motility spermatozoa severely impaired; embryo biopsy polymerase chain...
Chloride channel accessory 1 (CLCA1) is a CLCA protein that plays functional role in regulating the differentiation and proliferation of colorectal cancer (CRC) cells. Here we investigated relationship between level CLCA1 prognosis CRC.First, was detected quantitatively normal cancerous colonic epithelial tissues with immunohistochemistry. Next, correlations expression, pathological tumor features, overall survival rate patients analyzed. Finally, 3 publicly available data sets from Gene...
Purpose To identify and characterize the sources of B 0 field changes due to head motion, reduce motion sensitivity in human brain MRI. Methods fields were measured 5 healthy volunteers at various poses. After measurement total field, originating from subject was calculated by subtracting external generated magnet shims. A subject‐specific susceptibility model created quantify contribution torso. The spatial complexity analyzed using spherical harmonic expansion. Results Minor pose can cause...
Abstract Cortical lesions are common in multiple sclerosis and associated with disability progressive disease. We asked whether cortical continue to form people stable white matter the association of worsening relates pre-existing or new lesions. Fifty adults no year prior enrolment (33 relapsing-remitting 17 progressive) a comparison group nine who had formed at least one lesion (active relapsing-remitting) were evaluated annually 7 tesla (T) brain MRI 3T spine for 2 years, clinical...
Abstract Background Diffusion‐weighted (DW) turbo‐spin‐echo (TSE) imaging offers improved geometric fidelity compared to single‐shot echo‐planar‐imaging (EPI). However, it suffers from low signal‐to‐noise ratio (SNR) and prolonged acquisition times, thereby restricting its applications in diagnosis MRI‐guided radiotherapy (MRgRT). Purpose To develop a joint k‐b space reconstruction algorithm for concurrent of DW‐TSE images the apparent diffusion coefficient (ADC) map with enhanced image...
The water exchange between brain parenchyma and cerebrospinal fluid (CSF) is considered to be responsible for glymphatic clearance of solutes metabolic wastes from the brain, including amyloid-β, a biomarker in neurodegeneration. Despite potential significance, no noninvasive technique vivo measurement parenchyma-CSF has been demonstrated humans, capable investigating age-related changes clearance. To demonstrate noninvasive, translatable MRI measuring humans apply this examine measures...