Dominic Arold

ORCID: 0000-0001-8029-8270
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About
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Research Areas
  • Eating Disorders and Behaviors
  • Diet and metabolism studies
  • Functional Brain Connectivity Studies
  • Advanced Thermodynamics and Statistical Mechanics
  • Regulation of Appetite and Obesity
  • Micro and Nano Robotics
  • Mental Health Research Topics
  • Autism Spectrum Disorder Research
  • Advanced Glycation End Products research
  • thermodynamics and calorimetric analyses
  • Stress Responses and Cortisol
  • Diet, Metabolism, and Disease
  • Child Nutrition and Feeding Issues
  • Neuroendocrine regulation and behavior
  • Advanced Neuroimaging Techniques and Applications
  • Liver Disease Diagnosis and Treatment
  • Particle Dynamics in Fluid Flows
  • Schizophrenia research and treatment
  • Tryptophan and brain disorders
  • Liver Disease and Transplantation
  • Adipose Tissue and Metabolism
  • stochastic dynamics and bifurcation
  • Ecosystem dynamics and resilience

TU Dresden
2023-2025

TransDeN Lab
2024

Friedrich-Alexander-Universität Erlangen-Nürnberg
2018-2020

Physical sequelae of anorexia nervosa (AN) include a marked reduction in whole brain volume and subcortical structures such as the hippocampus. Previous research has indicated aberrant levels inflammatory markers growth factors AN, which other populations have been shown to influence hippocampal integrity.

10.1017/s0033291724000394 article EN cc-by Psychological Medicine 2024-03-07

Abstract Background Schizophrenia is associated with an increased risk of aggressive behaviour, which may partly be explained by illness-related changes in brain structure. However, previous studies have been limited group-level analyses, small and selective samples inpatients long time lags between exposure outcome. Methods This cross-sectional study pooled data from 20 sites participating the international ENIGMA-Schizophrenia Working Group. Sites acquired T1-weighted diffusion-weighted...

10.1101/2024.02.04.24302268 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-02-05

Abstract Previous studies of brain structure in anorexia nervosa (AN) have reported reduced gray matter underweight patients, which largely normalizes upon weight gain. One underlying biological mechanism may be glial cell alterations related to low-grade inflammation. Here, we investigated relationships between as measured by magnetic resonance imaging and serum concentrations two pro-inflammatory cytokines (interleukin-6 tumor necrosis factor alpha) cross-sectionally 82 adolescent young...

10.1038/s41386-024-01836-z article EN cc-by Neuropsychopharmacology 2024-03-09

We investigate the occurrence of heat leakages in overdamped Brownian harmonic systems. exactly compute underdamped and stochastic heats exchanged with bath for a sudden frequency or temperature switch. show that reduces to corresponding expression limit large friction isothermal process. However, we establish this is not case isochoric transformation. microscopically derive additionally generated leakage relate its origin initial relaxation velocity system. Our results highlight limitations...

10.1103/physreve.97.022131 article EN Physical review. E 2018-02-20

Abstract Background Anorexia nervosa (AN) is characterized by sizable, widespread gray matter (GM) reductions in the acutely underweight state. However, evidence for persistent alterations after weight-restoration has been surprisingly scarce despite high relapse rates, frequent transitions to other psychiatric disorders, and generally unfavorable outcome. While most studies investigated brain regions separately (univariate analysis), disorders can be conceptualized as network multivariate...

10.1017/s0033291723001861 article EN cc-by Psychological Medicine 2023-08-09

Many active matter systems, especially on the microscopic scale, are well approximated as overdamped, meaning that any inertial momentum is immediately dissipated by environment. On other hand, for macroscopic systems but also many mesoscopic time scale of motion can become large enough to be relevant dynamics. This raises question how collective dynamics and resulting states in influenced inertia. Therefore, we propose a coarsegrained continuum model underdamped based mean field description...

10.1088/1361-648x/ab849b article EN cc-by Journal of Physics Condensed Matter 2020-05-11

Resting-state functional connectivity analysis has been used to study disruptions in neural circuitries underlying eating disorder symptoms. Research shown resting-state be altered during the acute phase of anorexia nervosa (AN), but little is known about biological mechanisms changes associated with weight restoration. The goal current was investigate longitudinal regional homogeneity (ReHo) among neighboring voxels, degree centrality (DC) (a voxelwise whole brain correlation coefficient),...

10.1016/j.bpsc.2024.01.006 article EN cc-by-nc-nd Biological Psychiatry Cognitive Neuroscience and Neuroimaging 2024-01-30

Steatotic liver disease (SLD) is characterized by excessive accumulation of lipids in the liver. It associated with elevated risk hepatic and cardiometabolic diseases, as well mental disorders such depression. Previous studies revealed global gray matter reduction SLD. To investigate a possible shared neurobiology depression, we examined fat-related regional alterations SLD its most significant clinical subgroup metabolic dysfunction-associated steatotic (MASLD).

10.1016/j.metabol.2024.155983 article EN cc-by Metabolism 2024-07-30

Active matter systems often are well approximated as overdamped, meaning that any inertial momentum is immediately dissipated by the environment. On other hand, especially for macroscopic but also many mesoscopic ones particle mass can become relevant dynamics. For such we recently proposed an underdamped continuum model which captures translationally dynamics via two contributions. First, convection and second a damping time scale of motion. In this paper, ask how both these features...

10.1140/epje/i2020-11971-x article EN cc-by The European Physical Journal E 2020-07-01

Abstract Objective The amygdaloid complex plays a pivotal role in emotion processing and has been associated with rumination transdiagnostically. In anorexia nervosa (AN), we previously observed differential reductions of amygdala nuclei volumes (rostral‐medial cluster substantially affected) and, another study, elevated food−/weight‐related rumination. Both frequency correlated characteristically suppressed leptin levels AN. Thus, hypothesized that alterations might be AN‐related...

10.1111/acps.13607 article EN cc-by Acta Psychiatrica Scandinavica 2023-09-08

Einleitung: Übermässige Kalorienzufuhr oder erhöhtes Alkoholkonsum sind die häufigste Ursache für Entwicklung einer steatotischen Lebererkrankung (SLD) durch vermehrte Akkumulation von Lipiden in der Leber. SLD ist mit einem erhöhten Risiko hepatische, kardiovaskuläre, metabolische als auch psychische Erkrankungen, wie Depression, verbunden. Frühere Studien zeigten eine globale Reduzierung grauen Substanz bei SLD. Um mögliche gemeinsame neurobiologische Mechanismen zwischen und Depression zu...

10.1055/s-0044-1785272 article DE Diabetologie und Stoffwechsel 2024-04-01
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