A5017073569- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Acupuncture Treatment Research Studies
- Pediatric health and respiratory diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Disease and Adiposity
- COVID-19 and Mental Health
- Anesthesia and Neurotoxicity Research
- Neurological Disease Mechanisms and Treatments
- Ovarian function and disorders
- Psychosomatic Disorders and Their Treatments
- Healthcare and Venom Research
- Cancer Risks and Factors
- Reproductive Biology and Fertility
- Birth, Development, and Health
- Optimism, Hope, and Well-being
- Medicinal Plants and Bioactive Compounds
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Regulation of Appetite and Obesity
- Infrared Thermography in Medicine
- Tryptophan and brain disorders
- Mitochondrial Function and Pathology
- Liver physiology and pathology
- Spine and Intervertebral Disc Pathology
Beijing University of Chinese Medicine
2018-2025
Xinjiang Medical University
2023-2025
Eastern Hepatobiliary Surgery Hospital
2023
First Affiliated Hospital of Xinjiang Medical University
2023
Second Military Medical University
2023
Air Force Medical University
2023
EY Technologies (United States)
2023
Unchained Labs (United States)
2023
UCLA Medical Center
2020
Harbor–UCLA Medical Center
2020
Perinatal nicotine exposure (PNE) induces pulmonary dysplasia in offspring and it increases the risk of respiratory diseases both across generations. The maternal gut microbiota its metabolites, such as short-chain fatty acids (SCFAs), can regulate fetal lung development are susceptible to exposure. Therefore, modulation PNE-induced changes SCFAs may prevent occurrence offspring. Our previous studies demonstrated that electroacupuncture (EA) ameliorated impairment development. To further our...
The issue of obesity is becoming more and prominent. Understanding the metabolic profile obese young adults finding possible risk markers for early prediction intervention great importance. A total 13,082 college students with an average age 20 years were enrolled in this cross-sectional study. lipid composition was measured novel profiles such as AIP, AI, LCI, Non-HDL-C, TC/HDL-C, LDL-C/HDL-C TyG calculated. Participants then assessed normal weight, overweight or based on their BMI. Pearson...
Background. Clinically, electroacupuncture (EA) is the most common therapy for aging-related cognitive impairment (CI). However, underlying pathomechanism remains unidentified. The aims of this study were to observe effect EA on function and explore potential mechanism by which acts NLRP3/caspase-1 signaling pathway. Main Methods. Thirty male SAMP8 mice randomly divided into model, 2 Hz 10 groups. Ten SAMR1 assigned control group. Cognitive was assessed through Morris water maze test....
Osteoarthritis (OA) is a common degenerative joint disease with higher prevalence in females than males. Sex may be key factor affecting the progression of OA. This study aimed to investigate critical sex-difference-related genes patients OA and confirm their potential roles regulation.OA datasets GSE12021, GSE55457, GSE36700 were downloaded from Gene Expression Omnibus database screen OA-causing that are differentially expressed two sexes. Cytoscape was used construct protein-protein...
Insulin receptor (InsR) signaling through transcription factor FoxO1 is important in the development of hypothalamic neuron feeding circuits, but knowledge about underlying mechanisms limited. To investigate role InsR/FoxO1 and maintenance these we surveyed pool neurons expressing Pomc mRNA different mouse models impaired InsR signaling. ablation entire hypothalamus did not affect Pomc-neuron number at birth, resulted a 25% increase, most notably middle arcuate nucleus region, young adults....
Prevention of bronchopulmonary dysplasia (BPD) in premature-birth babies continues to be an unmet medical need. Intramuscular vitamin A is currently employed preterm neonates prevent BPD but requires intramuscular injections fragile neonates. We hypothesized that noninvasive inhaled delivery A, targeted lung, would a more effective and tolerable strategy. our well-established hyperoxia-injury neonatal rat model, exposing newborn rats 7 days constant extreme (95% O2) hyperoxia, comparing...
Sagacious Confucius’ Pillow Elixir (SCPE) is a traditional Chinese medicine that mainly used for cognitive impairment in aging; however, the underlying mechanisms remain unclear. Aging one of most important pathogenic factors leading to inflammation and pyroptosis hippocampus, which may be potential mechanism elderly patients with impairment. Here, we examined whether SCPE could improve SAMP8 mice by reducing hippocampal pyroptosis. Seven-month-old senescence-accelerated P8 (SAMP8) received...
Many factors during pregnancy can induce intrauterine growth restriction (IUGR), resulting in various adverse perinatal outcomes such as low birth weight and multiple organ disorders. Among these factors, prenatal smoke/nicotine exposure is a common cause of IUGR, often associated with altered fetal lung development. The classical Wnt signaling pathway plays vital role development, its alterations are commonly developmental pathologies. purpose this study was to determine whether...
In this paper, the theory of "Fear injury kidney" in traditional Chinese medicine is systematically reviewed, and it found that long-term or excessive psychological changes fear are likely to damage kidney qi essence. On basis, studies patients, medical staff public during COVID-19 epidemic China were analyzed, psychology was be prevalent among all kinds people. Modern researches on have also could cause neuro-endocrine-immune system, which can induce diseases susceptibility some diseases....
Introduction . Environmental exposure of the developing offspring to cigarette smoke or nicotine is an important predisposing factor for many chronic respiratory conditions, such as asthma, emphysema, pulmonary fibrosis, and so forth, in exposed offspring. Studies showed that electroacupuncture (EA) applied maternal “Zusanli” (ST36) acupoints during pregnancy lactation protects against perinatal exposure‐ (PNE‐) induced lung damage. However, most effective time period, is, prenatal vs....
Background . Maternal smoking and/or exposure to environmental tobacco smoke continue be significant factors in fetal and childhood morbidity are a serious public health issue worldwide. Nicotine passes through the placenta easily with minimal biotransformation, entering circulation, where it results many harmful effects on developing offspring, especially respiratory system. Objectives Recently, rat model, electroacupuncture (EA) at maternal acupoints ST 36 has been shown block perinatal...
Local acupuncture has been found to have a good analgesic effect in rats with cervical spondylosis radiculopathy (CSR), but it lacks regulatory on traditional Chinese medicine syndrome types of CSR. We proposed "Invigorating Qi and activating Blood" (IQAB) acupuncture, compared Fenbid, local electroacupuncture (LEA), observe whether advantages the protection CSR rat model elucidate its mechanism through MAPK (mitogen-activated protein kinase) signaling pathway.Male Sprague-Dawley were...
Maternal food restriction (MFR) during pregnancy leads to pulmonary dysplasia in the newborn period and increases susceptibility diseases, such as asthma chronic lung disease, later life. Previous studies have shown that maternal electro-acupuncture (EA) applied “Zusanli” (ST 36) could prevent abnormal expression of key developmental signaling pathways improve morphology function perinatal nicotine exposed offspring. There is a significant overlap affected by exposure MFR pregnancy; however,...
To compare the different effect of electroacupuncture (EA) at "Zusanli" (ST36) and "Chize" (LU5) mother rats exposed to Nicotine during pregnancy lactation on lung function morphological changes in offspring rats, so as explore most effective acupoint for improving development neonatal rats.A total 24 female SD were randomly divided into 4 groups: normal control, model, EA-ST36 EA-LU5 (n＝6 each group). Rats group treated by subcutaneous injection saline, those other 3 groups nicotine (1...
Type 2 diabetes mellitus (T2DM) is the leading threat to human health in China, and severe cognitive impairment often occurs most T2DM patients. Although Sagacious Confucius' Pillow Elixir a type of classical traditional Chinese medicine for clinic, mechanism has not yet been completely defined. In this study, an experimental model was established by injecting Sprague Dawley (SD) rats with streptozocin (STZ), so as compare learning memory ability, hippocampal neurons pathological changes,...
Abstract Maternal food restriction (MFR) during pregnancy leads to pulmonary dysplasia in the newborn period and increases susceptibility diseases, such as asthma chronic lung disease, later life. Previous studies have shown that maternal electro‐acupuncture (EA) applied “Zusanli” (ST 36) could prevent abnormal expression of key developmental signaling pathways improve morphology function perinatal nicotine exposed offspring. There is a significant overlap affected by exposure MFR pregnancy;...
To investigate the effect of electroacupuncture (EA) acupoints Neiguan (PC 6) and Tianquan 2) on skin temperature, blood perfusion, alpha1- beta2-adrenoreceptor (α1-AR β2-AR) protein mRNA level in rats with acute myocardial ischemia.Thirty male adult Wistar [(230 ± 20) g] were randomly assigned into five groups (n = 6 each): a control group, sham operation model group treated EA at low frequency (L-EA, 2 Hz, 1 mA) high (H-EA, 100 mA). The rat was prepared by ligating left anterior descending...
To compare the effects of electroacupuncture (EA) at "Zusanli" (ST 36) versus "Yanglingquan" (GB 34) in pregnant rats on perinatal nicotine-exposure-induced lung function and morphology newborn explore rule acupoint effect EA for prevention from dysplasia rats.A total 24 female SD were randomized into a normal saline group (S group), nicotine (N nicotine-ST 36 + ST group) nicotine-GB 34 (N+GB 6 each one. Starting 6th day pregnancy, 0.9% sodium chloride solution was injected subcutaneously S...