A5039709336- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Management of metastatic bone disease
- Nonmelanoma Skin Cancer Studies
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Ovarian cancer diagnosis and treatment
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Head and Neck Cancer Studies
- BRCA gene mutations in cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Ear and Head Tumors
- Bone Tissue Engineering Materials
- Cancer and Skin Lesions
- Central Venous Catheters and Hemodialysis
- Uterine Myomas and Treatments
- MRI in cancer diagnosis
- Vascular Malformations and Hemangiomas
- Colorectal and Anal Carcinomas
Miami Transplant Institute
2023
Cancer Institute of Florida
2015-2020
Hospital Universitario de Gran Canaria Doctor Negrín
2015
Cancer Institute (WIA)
2015
Dattoli Cancer Center and Brachytherapy Research Institute
2008-2010
Institut Jules Bordet
2004
The concept of spatially fractionated radiation therapy (SFRT) was conceived over 100 years ago, first in the form GRID, which has been applied to clinical practice since its early inception and continued present even with markedly improved instrumentation therapy. LATTICE (LRT) introduced 2010 as a conceptual 3D extension GRID several uniquely different features. Since 2014, when patient treated, 150 patients bulky tumors worldwide have received LRT. Through brief review basic principles...
Objective Lattice radiotherapy (LRT) is a novel technique of delivering heterogeneous doses radiation to voluminous tumors not amenable surgery. Built from the conventional two-dimensional grid, LRT utilizes power new technology, three-dimensional allowing delivery higher small spheres, also called vertices, inside bulky while limiting exposure surrounding healthy tissue. The main goals study were evaluation tumor response and overall safety in this cohort patients with non-small cell lung...
The objective of this teaching case is to report the excellent results using lattice radiation therapy (LTR) for treatment a large metastasis from ovarian carcinosarcoma. This new technical concept extrapolates traditional spatially fractionated (GRID) technique advanced three-dimensional (3D) high-dose modern instrumentation in oncology. We 61-year-old female with metastatic mass carcinosarcoma treated by procedure clinical and image-based follow-up more than four years.
The Lattice Radiotherapy (LRT) technique is mainly based on the GRID technology with improved feature of 3D treatment delivery. A 72 year old male presented left shoulder pain due to a 6 cm pulmonary mass in upper lobe (LUL) histologically proven Non-Small Cell Lung Cancer (NSCLC) stage IIIA. In July 2011 he was treated our center LRT followed by conventional fractionated Volumetric Modulated Arc Therapy (VMAT) combined chemotherapy. Clinical and imaging follow up years demonstrated...
Spatially fractionated radiation therapy (SFRT) has shown promise in generating high tumor response and local control the treatment of various palliative locally advanced bulky tumors. SFRT not yet been studied systematically cancer cervix. Here we report first series patients receiving for advanced/bulky cervical cancer. Ten with far-advanced cancer, stage IIIB–IVA (seven squamous cell three adeno/adenosquamous carcinomas) received lattice (LRT), a variant SFRT. The LRT regimen consisted...
PurposeSpatially fractionated radiation therapy (SFRT) is increasingly used for bulky advanced tumors, but specifics of clinical SFRT practice remain elusive. This study aimed to determine patterns GRID and Lattice (LRT) based SFRT.Materials MethodsA survey was designed identify oncologists' patient selection SFRT, dosing/planning, dosimetric parameter use, platforms/techniques, combinations with conventional external beam (cERT) multimodality therapies, physicists' technical implementation,...
Background: We report the case of a patient with an advanced carcinoma cervix treated using new concept LATTICE Radiotherapy (LRT). describe dose distribution, planning and delivery treatment as well clinical evaluation during at completion treatment. The basic principle is to create, within tumor volume, multiple localized high-dose islands certain degree separation form lower regions. Methods: This based on 48-year-old female, G1P1, who presented cervical bulky pelvic mass. was Trilogy...
Despite the unexpectedly high tumor responses and limited treatment-related toxicities observed with SFRT, prospective multi-institutional clinical trials of SFRT are still lacking. High variability technologies methods, unfamiliar complex dose prescription concepts for heterogeneous uncertainty regarding systemic therapies present major obstacles towards trial development. To address these challenges, consensus guideline reported here aimed at facilitating development feasibility through a...
Total scalp irradiation may be used to treat numerous conditions including squamous and basal cell carcinomas.These are relatively uncommon patients frequently treated with palliative intent.In this report, we describe a volumetric arc therapy technique using photon beams for curative intent in an 84 years old patient recurrent carcinoma of the scalp.Dose was 50Gy (2Gy per session) planning target volume (PTV) followed by 10 Gy boost macroscopic disease on forehead.A custom made 1 cm...
Background: The purpose of this study was to determine if stereotactic body radiosurgery (SBRT) using volumetric modulated arc therapy (VMAT) can be used deliver a boost the vaginal cuff in patients with gynecological cancer as an alternative high dose rate (HDR) brachytherapy. Methods: Between January and July 2009, five were treated postoperative radiation whole pelvis doses ranging from 41.4 Gy 45 Gy. This followed SBRT VMAT. total delivered ranged 9 21 given three fractions. Plan...