- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Functional Brain Connectivity Studies
- Legionella and Acanthamoeba research
- Dementia and Cognitive Impairment Research
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Action Observation and Synchronization
- Water Treatment and Disinfection
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Multiple Sclerosis Research Studies
- Neurobiology of Language and Bilingualism
- Alzheimer's disease research and treatments
- Building Energy and Comfort Optimization
- Radiopharmaceutical Chemistry and Applications
- Bone and Joint Diseases
- Genetic Neurodegenerative Diseases
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Boron Compounds in Chemistry
- NMR spectroscopy and applications
- Motor Control and Adaptation
- Bacterial biofilms and quorum sensing
Siemens Healthcare (Germany)
2020-2024
University of Bari Aldo Moro
2010-2024
Siemens (United Kingdom)
2018-2024
Polytechnic University of Turin
2023
Cardiff University
2018-2023
Regione Puglia
2021
Siemens Healthcare (United States)
2020
University of Parma
2011-2018
Istituti di Ricovero e Cura a Carattere Scientifico
2002-2016
SDN Istituto di Ricerca Diagnostica e Nucleare
2016
Semantic memory decline and changes of default mode network (DMN) connectivity have been reported in Mild Cognitive Impairment (MCI).Only a few studies, however, investigated the role activity DMN semantic this clinical condition.The present study aimed to investigate more extensively relationship between impairment intrinsic MCI.Twenty-one MCI patients twenty-one healthy elderly controls matched for demographic variables took part study.All participants underwent comprehensive battery...
Globally, at the time of writing (20 March 2021), 121.759.109 confirmed COVID-19 cases have been reported to WHO, including 2.690.731 deaths. on 18 2021, a total 364.184.603 vaccine doses administered. In Italy, 3.306.711 with 103.855 deaths WHO. 9 6.634.450 On 15 Italian Medicines Agency (AIFA) decided temporarily suspend use AstraZeneca throughout country as precaution, pending rulings European (EMA). This decision was taken in line similar measures adopted by other countries due death...
Abstract Echo‐planar imaging is the most widely used sequence for functional magnetic resonance (fMRI) due to its fast acquisition. However, it prone local distortions, image blurring, and signal voids. As these effects scale with echo train length field strength, essential high‐resolution echo‐planar at ultrahigh address problems. Partially parallel acquisition methods can be improve quality of imaging. partially affected by aliasing artifacts noise enhancement. Another way shorten reduce...
Following the publication of Italian Guidelines for control and prevention legionellosis an environmental clinical surveillance has been carried out in Southeastern Italy. The aim study is to identify risk factors disease, so allowing better programming necessary measures. During period January 2000 - December 2009 was by water sampling 129 health care facilities (73 public 56 private hospitals) 533 buildings within community (63 apartments, 305 hotels, 19 offices, 4 churches, 116 gyms, 3...
Abstract Aging leads to gray and white matter decline but their causation remains unclear. We explored two classes of models age dementia risk related brain changes. The first class emphasises the importance matter: risk-related processes cause neurodegeneration this causes damage in associated tracts. second reverses direction causation: aging factors damage. compared these with linear mediation analysis quantitative MRI indices (from diffusion, magnetization transfer relaxometry imaging)...
This work reports for the first time on implementation and application of cardiac diffusion-weighted MRI a Connectom MR scanner with maximum gradient strength 300 mT/m. It evaluates benefits increased performance investigation myocardial microstructure.
Purpose: Diffusion tensor imaging (DTI) is commonly used in cardiac diffusion magnetic resonance (dMRI). However, the tissue's microstructure (cells, membranes, etc.) restricts movement of water molecules, making spin displacements deviate from Gaussian behaviour. This effect may be observed with kurtosis (DKI) using sufficiently high b-values (b > 450 s/mm 2 ), which are presently outside realm routine dMRI due to limited gradient strength clinical scanners. The Connectom scanner G max =...
Action and speech may take different forms, being expressed, for example, gently or rudely. These aspects of social communication, named vitality have been little studied in neuroscience. In the present functional magnetic resonance imaging study, we investigated role insula processing action forms. runs, participants were asked to listen themselves pronounce verbs they observe perform actions The results showed that, relative controls, there was an activation dorso-central both tasks runs....
We provide a rich multi-contrast microstructural MRI dataset acquired on an ultra-strong gradient 3T Connectom scanner comprising 5 repeated sets of contrasts in 6 healthy human participants. The availability data that support comprehensive simultaneous assessment test-retest reliability multiple (i.e., those derived from advanced diffusion, multi-component relaxometry and quantitative magnetisation transfer MRI) the same population is extremely limited. This unique offered to imaging...
The COVID-19 pandemic started in China early December 2019, and quickly spread around the world. epidemic gradually Italy at end of February 2020, by May 31, 232,664 cases 33,340 deaths were confirmed. As a result this pandemic, Italian Ministerial Decree issued on March 11, enforced lockdown; therefore, many social, recreational, cultural centers remained closed for months. In Apulia (southern Italy), all non-urgent hospital activities suspended, some wards closed, with consequent reduction...
Abstract Background The practice of tattooing and piercing has expanded in western society. In order to verify young adults' knowledge the risk practices related body art, an investigation was conducted among freshmen University Bari region Apulia, Italy. Methods study carried out Academic Year 2009-2010 through anonymous self-administered written questionnaire distributed 1.656 enrolled 17 Degree Courses. Results Of 1.598 students included analysis, 78.3% believe it is risky undergo...
Spatial abilities decline in normal aging and decrease faster earlier Alzheimer's disease (AD), but these deficits are under investigated. The main goals of this study were to assess visuospatial memory mild cognitive impairment (
Dual-calibrated fMRI is a multi-parametric technique that allows for the quantification of resting oxygen extraction fraction (OEF), absolute rate cerebral metabolic consumption (CMRO
Legionella is the causative agent of Legionnaires' disease, a flu-like illness normally acquired following inhalation or aspiration contaminated water aerosols. Our recent studies revealed that climatic parameters can increase number reported cases community-acquired disease. Here, we evaluated presence in networks and distribution disease associated with touristic-recreational facilities Apulia region (southern Italy) during period 2001-2017 using geostatistical analyses. Geostatistical...
Semantic memory decline has been found in Mild Cognitive Impairment (MCI). In this study performance on a range of semantic tasks and structural brain patterns were examined group MCI patients. Fourteen sixteen healthy elderly controls underwent assessment MRI scanning. The cognitive battery included visual naming from definition for objects, actions famous people, fluency animals, fruits, tools, furniture, singers, politicians, actions, word-association task early late acquired words...
An observation/execution matching system for walking has not been assessed yet. The present fMRI study was aimed at assessing whether, as object-directed actions, an is active and whether the spatial context of (open or narrow space) recruits different neural correlates. Two experimental conditions were employed. In execution condition, while being scanned, participants performed on a rolling cylinder located just outside scanner. same action also observing video presenting either open space...
Midlife obesity is a risk factor of late onset Alzheimer's disease (LOAD) but why this the case remains unknown. As systemic inflammation involved in both conditions, obesity-related neuroinflammation may contribute to damage limbic structures important LOAD. Here, we investigated hypothesis that would mediate central related effects on tissue microstructure 166 asymptomatic individuals (38–71 years old). We employed MRI indices sensitive myelin and [macromolecular proton fraction (MPF) kf]...
Here we propose a new magnetic resonance (MR) strategy based on the evaluation of internal gradient (G(i)) to assess trabecular bone (TB) density in spongy bone. Spongy is porous system characterized by solid network immersed marrow and different relative percentage water fats. Using 9.4 T MR micro-imaging system, first evaluated fat G(i) as extracted from Spin-Echo decay function vitro femoral head samples calves. Indeed, differential effects diffusion result types behavior. clinical 3T...
Precise kinematics or body configuration cannot be recovered from visual input without disparity information. Yet, no imaging study has investigated the role of on action observation. Here, we interaction between and main cues biological motion, configuration, in two fMRI experiments. Stimuli were presented as point-light figures, depicting complex sequences lasting 21 s. We hypothesized that interactions could occur at any three levels observation network, comprising occipitotemporal,...