A5003398351- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Organ Transplantation Techniques and Outcomes
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Transplantation: Methods and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Cancer Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Viral-associated cancers and disorders
- Multiple and Secondary Primary Cancers
- Congenital Anomalies and Fetal Surgery
- Neuroendocrine Tumor Research Advances
- Colorectal Cancer Treatments and Studies
- Hepatitis B Virus Studies
- Abdominal Surgery and Complications
- Genetic and Kidney Cyst Diseases
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Minimally Invasive Surgical Techniques
- Abdominal Trauma and Injuries
Onomichi General Hospital
2020-2025
Hiroshima University
2013-2023
Hiroshima Prefectural Hospital
2016-2023
Life Science Institute
2017-2018
Hiroshima University Hospital
2008-2016
National Cancer Center Hospital East
2016
Hiroshima General Hospital
2015
American Gastroenterological Association
2011
Fundación Juan March
2009
Hôpitaux Universitaires de Strasbourg
2009
<i>Background:</i> Splenectomy is gaining increasing importance for cirrhotic patients with hypersplenism. However, its safety and efficacy chronic liver disease remain unclear. <i>Methods:</i> We retrospectively examined the medical records of 38 consecutive who underwent splenectomy or simultaneous hepatectomy hepatocellular carcinoma. <i>Results:</i> White blood cell platelet counts significantly increased 3 months after splenectomy. Serum levels total...
Previous retrospective studies have demonstrated the effectiveness of parenchymal pre-compression in reducing pancreatic fistula after left-sided resection; however, no multicentre RCT has been conducted. The aim this study was to investigate whether reduces grade B/C resection. Between 23 March 2021 and 26 January 2023, patients scheduled for resection were enrolled a at 13 hospitals Japan. These randomly assigned (1 : 1) group or non-compression group. primary endpoint incidence secondary...
Abstract Background: Dvl is a cytoplasmic protein to regulate the stability of β‐catenin in Wnt signalling pathway. However, molecular mechanism by which regulates pathway not fully understood. Results: We identified novel that binds and named it Daple. Daple consisted 2009 amino acids with high frequency leucine residues formed homo‐oligomer. The C‐terminal three were necessary for binding region containing PDZ domain Dvl. Expression mouse fibroblast L cells inhibited Wnt‐3a‐induced...
Background The purpose of this study was to evaluate both safety diet-treated donors and the feasibility their use for living-donor liver transplantation (LDLT). Methods A total 128 living were enrolled in between April 2003 March 2010. Of them, 41 diagnosed with hepatic steatosis at initial consultation. Donor selection based on findings biopsy accompanied normalization function tests after diet treatment consisting an 800 1400 kcal/day a 100 400 exercise without drug treatment, targeting...
Abstract Background The preferred choice between surgical treatment and radiofrequency ablation (RFA) for the of small resectable hepatocelluar carcinoma (HCC) has become a subject debate. Methods We compared results hepatic resection (n = 199) with those RFA 87), which 69 patients were treated transcatheter arterial chemoembolization followed by RFA, 286 3 or fewer nodules, none exceeded cm in diameter at Hiroshima University Hospital. Results In subgroup analysis single HCC tumor size...
Small-for-size syndrome remains the greatest limiting factor of expanding segmental liver transplantation from living donors. Portal hyperperfusion is considered to substantially contribute small-for-size syndrome. We investigated impact continuous portal infusion prostaglandin E1 (PGE1) on grafts (SFSGs) in adult-to-adult living-donor (LDLT).From July 2003 December 2009, LDLT was performed 122 patients. introduced PGE1 five SFSG patients (PG group) November 2007 2009 and retrospectively...
This study aimed to investigate the association between a new biomarker that incorporates albumin (Alb) and butyrylcholinesterase (BCHE) levels, as well prognosis of hepatocellular carcinoma (HCC) after hepatectomy.
Abstract Aims This study examined the long‐term quality of life (QOL) living liver donors (LLDs) in Japan using both generic and LLD‐specific instruments. Methods The sample comprised 374 LLDs from five university hospitals who underwent surgery more than a year previously. QOL was evaluated Short Form‐36 health survey (SF‐36) LLD‐QOL scale. Results SF‐36 results indicated that overall significantly better Japanese standard. When comparing by donor factors, whose recipients were children...
Although many factors related to the tumor or hepatic functional reserve may affect outcome of partial hepatectomy for hepatocellular carcinoma (HCC), these have not yet been intensively investigated in patients with solitary HCC. The purpose this study is determine clinicopathological influencing long-term outcomes HCC.Data on 266 consecutive a HCC who underwent curative between 1997 and 2006 were analyzed regard prognosis.Overall survival rates at 3, 5, 10 years 89.5, 79.6, 56.1%,...
Minimally invasive thoracoscopic esophagectomy has potential advantages in minimizing the impairment of respiratory function and reducing surgical stress. However, occasionally results anesthesia-induced hypothermia, particularly cases involving artificial pneumothorax with CO2. Thermogenesis induced by amino acid administration been reported during anesthesia. Here, we tested efficacy treatment for prevention investigated this to reduce postoperative infectious complications after...