A5031639501- T-cell and B-cell Immunology
- Glycosylation and Glycoproteins Research
- Ubiquitin and proteasome pathways
- Cytomegalovirus and herpesvirus research
- Cancer-related gene regulation
- Blood groups and transfusion
- Epigenetics and DNA Methylation
- Cancer-related Molecular Pathways
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Bladder and Urothelial Cancer Treatments
- Protein Degradation and Inhibitors
- Management of metastatic bone disease
- Bone health and treatments
- Circular RNAs in diseases
- Extracellular vesicles in disease
- vaccines and immunoinformatics approaches
- MicroRNA in disease regulation
- Medical Imaging Techniques and Applications
University of Duisburg-Essen
2024
Dokuz Eylül University
2021-2023
Izmir University
2021-2022
Lusaka Apex Medical University
2021
Tabular data, often scattered across multiple tables, is the primary output of data analyses in virtually all scientific fields. Exchange and communication tabular therefore a central challenge. We present Datavzrd, tool for creating portable, visually rich, interactive reports from any kind discipline. Datavzrd unifies strengths currently common generic approaches visualization like R Shiny with portability, ease use sustainability plain spreadsheets. The generated do not require...
Abstract Bladder cancer is mostly present in the form of urothelium carcinoma, causing over 150,000 deaths each year. Its histopathological classification as muscle invasive (MIBC) and non-muscle (NMIBC) most prominent aspect, affecting prognosis progression this disease. In study, we defined active regulatory landscape MIBC NMIBC cell lines using H3K27ac ChIP-seq used an integrative approach to combine our findings with existing data. Our analysis revealed FRA1 FLI1 two critical...
Hepatocyte dedifferentiation is a major source of hepatocellular carcinoma (HCC), but its mechanisms are unknown. We explored the p73 expression in HCC tumors and studied effects transcriptionally active p73β (TAp73β) cells. Expression profiles patient clinical data were collected from Genomic Data Commons (GDC) portal TSVdb database, respectively. Global gene determined by pan-genomic 54K microarrays. The Gene Set Enrichment Analysis method was used to identify TAp73β-regulated sets. TAp73...
<title>Abstract</title> Background Identification of Human leukocyte antigen (HLA) types from DNA-sequenced human samples is important in organ transplantation and cancer immunotherapy remains a challenging task considering sequence homology extreme polymorphism HLA genes. Results We present Orthanq, novel statistical model corresponding application for transparent uncertainty-aware quantification haplotypes. utilize our approach to perform typing while, the first time, reporting uncertainty...
Abstract Background Identification of human leukocyte antigen (HLA) types from DNA-sequenced samples is important in organ transplantation and cancer immunotherapy remains a challenging task considering sequence homology extreme polymorphism HLA genes. Results We present Orthanq, novel statistical model corresponding application for transparent uncertainty-aware quantification haplotypes. utilize our approach to perform typing while, the first time, reporting uncertainty predictions...
Abstract Bladder cancer is mostly present in the form of urothelium carcinoma, causing over 150,000 deaths each year. Its histopathological classification as muscle invasive (MIBC) and non-muscle (NMIBC) most prominent aspect, affecting prognosis progression this disease. In study, we defined active regulatory landscape MIBC NMIBC cell lines using H3K27ac ChIP-seq used an integrative approach to combine our findings with existing data. Our analysis revealed FRA1 FLI1 two critical...
Abstract Purpose Hepatocellular carcinoma (HCC) is one of the leading causes cancer-related death worldwide with. lack effective systemic chemotherapy. In this study, we aimed to evaluate value ATPase family AAA domain-containing protein 2 (ATAD2) as a biomarker and potential therapeutic target for HCC. Methods The expression ATAD2 was tested in different HCC patient cohorts by immunohistochemistry comparative transcriptional analysis. co-expression proliferation markers compared during...